Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

Glutamine transporters in mammalian cells and their functions in physiology and cancer

(2016) Yangzom D. Bhutia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Concise Guide to PHARMACOLOGY 2015/16: Transporters

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs

(2015) Y. D. Bhutia et al.   CANCER RESEARCH

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

(2015) Christopher Southan et al.   NUCLEIC ACIDS RESEARCH

Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma

(2015) Alan R. Penheiter et al.   Biomed Research International

The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

(2014) Yangzom D. Bhutia et al.   Asian Journal of Pharmaceutical Sciences

Physical Biology in Cancer. 4. Physical cues guide tumor cell adhesion and migration

(2013) Kimberly M. Stroka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

(2013) Luika A. Timmerman et al.   CANCER CELL

Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer

(2013) G. Zhang et al.   CLINICAL CANCER RESEARCH

Imaging Tumour ATB0,+ Transport Activity by PET with the Cationic Amino Acid O-2((2-[18F]fluoroethyl)methyl-amino)ethyltyrosine

(2013) Adrienne Müller et al.   MOLECULAR IMAGING AND BIOLOGY

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Analysis of Precursor Lesions in Familial Pancreatic Cancer

(2013) Tatjana Crnogorac-Jurcevic et al.   PLoS One

Nutrient signaling to mTOR and cell growth

(2013) Jenna L. Jewell et al.   TRENDS IN BIOCHEMICAL SCIENCES

The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

(2012) Veena Coothankandaswamy et al.   BIOCHEMICAL JOURNAL

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells

(2012) Sayka Barry et al.   CLINICAL & EXPERIMENTAL METASTASIS

Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer

(2012) Timothy R. Donahue et al.   CLINICAL CANCER RESEARCH

Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

(2012) D. A. Altomare et al.   CURRENT MEDICINAL CHEMISTRY

Differential Expression of Metabolic Genes in Tumor and Stromal Components of Primary and Metastatic Loci in Pancreatic Adenocarcinoma

(2012) Nina V. Chaika et al.   PLoS One

Developments in metastatic pancreatic cancer: Is gemcitabine still the standard?

(2012) Jie-Er Ying   WORLD JOURNAL OF GASTROENTEROLOGY

α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions

(2011) Diane C Chugani   Biomarkers in Medicine

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

(2011) Takatsugu Ishimoto et al.   CANCER CELL

mTOR signaling in protein homeostasis

(2011) Crystal S. Conn et al.   CELL CYCLE

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer

(2011) Senthil Karunakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

CXCL17 and ICAM2 Are Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis

(2010) Nobuyoshi Hiraoka et al.   GASTROENTEROLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

Gemcitabine chemoresistance in pancreatic cancer: Molecular mechanisms and potential solutions

(2009) Roland Andersson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

(2008) Senthil Karunakaran et al.   BIOCHEMICAL JOURNAL

Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma

(2008) Masaki Miyazawa et al.   PATHOLOGY INTERNATIONAL

Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond

(2008) Vadivel Ganapathy et al.   PHARMACOLOGY & THERAPEUTICS