Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens

Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress–Induced Depressive Behaviors

(2016) Ja Wook Koo et al.   BIOLOGICAL PSYCHIATRY

Cav 1.3 (CACNA1D ) L-type Ca2+ channel dysfunction in CNS disorders

(2016) Alexandra Pinggera et al.   JOURNAL OF PHYSIOLOGY-LONDON

L-type Ca2+ channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes

(2016) Z. D. Kabir et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synaptic mechanisms underlying persistent cocaine craving

(2016) Marina E. Wolf   NATURE REVIEWS NEUROSCIENCE

Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability

(2016) Melis Inan et al.   NEUROBIOLOGY OF DISEASE

Multiple faces of BDNF in cocaine addiction

(2015) Xuan Li et al.   BEHAVIOURAL BRAIN RESEARCH

CACNA1D De Novo Mutations in Autism Spectrum Disorders Activate Cav1.3 L-Type Calcium Channels

(2015) Alexandra Pinggera et al.   BIOLOGICAL PSYCHIATRY

Reward processing dysfunction in major depression, bipolar disorder and schizophrenia

(2015) Alexis E. Whitton et al.   CURRENT OPINION IN PSYCHIATRY

L-type Ca2+ channel blockade with antihypertensive medication disrupts VTA synaptic plasticity and drug-associated contextual memory

(2015) M Degoulet et al.   MOLECULAR PSYCHIATRY

Targeting voltage-gated calcium channels in neurological and psychiatric diseases

(2015) Gerald W. Zamponi   NATURE REVIEWS DRUG DISCOVERY

Sufficiency of Mesolimbic Dopamine Neuron Stimulation for the Progression to Addiction

(2015) Vincent Pascoli et al.   NEURON

Cell-Type Specific Insertion of GluA2-Lacking AMPARs with Cocaine Exposure Leading to Sensitization, Cue-Induced Seeking and Incubation of Craving

(2015) Jean Terrier et al.   NEUROPSYCHOPHARMACOLOGY

Rare variants in neuronal excitability genes influence risk for bipolar disorder

(2015) Seth A. Ament et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and structural deficits at accumbens synapses in a mouse model of Fragile X

(2015) Daniela Neuhofer et al.   Frontiers in Cellular Neuroscience

Regulation of Postsynaptic Stability by the L-type Calcium Channel CaV1.3 and its Interaction with PDZ Proteins

(2015) Ruslan Stanika et al.   Current Molecular Pharmacology

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Stress and VTA synapses: implications for addiction and depression

(2014) Abigail M. Polter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons

(2014) Jeremy M. Reimers et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice

(2014) Ryota Araki et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

GABAergic and glutamatergic efferents of the mouse ventral tegmental area

(2014) Seth R. Taylor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area

(2014) Yudan Liu et al.   JOURNAL OF NEUROPHYSIOLOGY

Contrasting forms of cocaine-evoked plasticity control components of relapse

(2014) Vincent Pascoli et al.   NATURE

Pathological circuit function underlying addiction and anxiety disorders

(2014) Andreas Lüthi et al.   NATURE NEUROSCIENCE

Bidirectional Modulation of Incubation of Cocaine Craving by Silent Synapse-Based Remodeling of Prefrontal Cortex to Accumbens Projections

(2014) Yao-Ying Ma et al.   NEURON

The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context

(2014) J.J. Walsh et al.   NEUROSCIENCE

Illicit dopamine transients: Reconciling actions of abused drugs

(2014) Dan P. Covey et al.   TRENDS IN NEUROSCIENCES

αCaMKII controls the establishment of cocaine's reinforcing effects in mice and humans

(2014) A C Easton et al.   Translational Psychiatry

Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation

(2013) Robert M. Post et al.   BRITISH JOURNAL OF PSYCHIATRY

Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving  FosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell

(2013) A. J. Robison et al.   JOURNAL OF NEUROSCIENCE

Calcium-Permeable AMPA Receptors in the Nucleus Accumbens Regulate Depression-Like Behaviors in the Chronic Neuropathic Pain State

(2013) Y. Goffer et al.   JOURNAL OF NEUROSCIENCE

Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving

(2013) Jessica A Loweth et al.   NATURE NEUROSCIENCE

Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

(2013) Brian R Lee et al.   NATURE NEUROSCIENCE

The brain reward circuitry in mood disorders

(2013) Scott J. Russo et al.   NATURE REVIEWS NEUROSCIENCE

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects

(2013) A J Robison et al.   NEUROPSYCHOPHARMACOLOGY

Psychostimulant-Induced Neuroadaptations in Nucleus Accumbens AMPA Receptor Transmission

(2013) R. C. Pierce et al.   Cold Spring Harbor Perspectives in Medicine

Forebrain elimination of cacna1c mediates anxiety-like behavior in mice

(2012) A S Lee et al.   MOLECULAR PSYCHIATRY

Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens

(2012) Byung Kook Lim et al.   NATURE

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

(2012) Kay M. Tye et al.   NATURE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure

(2011) Miao-Xin Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Brain-derived neurotrophic factor rapidly increases AMPA receptor surface expression in rat nucleus accumbens

(2011) Xuan Li et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cav1.2 L-Type Ca2+ Channels Mediate Cocaine-Induced GluA1 Trafficking in the Nucleus Accumbens, a Long-Term Adaptation Dependent on Ventral Tegmental Area Cav1.3 Channels

(2011) K. Schierberl et al.   JOURNAL OF NEUROSCIENCE

Calcium-Permeable AMPA Receptors Are Present in Nucleus Accumbens Synapses after Prolonged Withdrawal from Cocaine Self-Administration But Not Experimenter-Administered Cocaine

(2011) J. E. McCutcheon et al.   JOURNAL OF NEUROSCIENCE

Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca2+-permeable AMPA receptors during the incubation of cocaine craving

(2011) Carrie R. Ferrario et al.   NEUROPHARMACOLOGY

Enhanced Dopamine D1 and BDNF Signaling in the Adult Dorsal Striatum but not Nucleus Accumbens of Prenatal Cocaine Treated Mice

(2011) Thomas F. Tropea et al.   Frontiers in Psychiatry

Molecular Switch from L-Type Cav1.3 to Cav1.2 Ca2+ Channel Signaling Underlies Long-Term Psychostimulant-Induced Behavioral and Molecular Plasticity

(2010) T. P. Giordano et al.   JOURNAL OF NEUROSCIENCE

Extinction Training after Cocaine Self-Administration Induces Glutamatergic Plasticity to Inhibit Cocaine Seeking

(2010) L. A. Knackstedt et al.   JOURNAL OF NEUROSCIENCE

ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses

(2010) Vincent Vialou et al.   NATURE NEUROSCIENCE

A genome-wide association study of alcohol dependence

(2010) L. J. Bierut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain-derived neurotrophic factor and cocaine addiction

(2009) Jacqueline F. McGinty et al.   BRAIN RESEARCH

CaV1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype

(2009) Perrine Busquet et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc

(2009) Manuel Mameli et al.   NATURE NEUROSCIENCE

Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior

(2008) Thomas F. Tropea et al.   JOURNAL OF NEUROCHEMISTRY

Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons

(2008) Bradley A. States et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

(2008) Kelly L. Conrad et al.   NATURE

A Biological Function for the Neuronal Activity-Dependent Component of Bdnf Transcription in the Development of Cortical Inhibition

(2008) Elizabeth J. Hong et al.   NEURON