Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving

Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche

(2013) Jessica A Loweth et al.   CURRENT OPINION IN NEUROBIOLOGY

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

(2013) Roland Bock et al.   NATURE NEUROSCIENCE

Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

(2013) Brian R Lee et al.   NATURE NEUROSCIENCE

Different Adaptations in AMPA Receptor Transmission in the Nucleus Accumbens after Short vs Long Access Cocaine Self-Administration Regimens

(2013) Anthony Purgianto et al.   NEUROPSYCHOPHARMACOLOGY

Animal Studies of Addictive Behavior

(2013) L. J. M. J. Vanderschuren et al.   Cold Spring Harbor Perspectives in Medicine

Preso1 dynamically regulates group I metabotropic glutamate receptors

(2012) Jia-Hua Hu et al.   NATURE NEUROSCIENCE

The persistence of maladaptive memory: Addiction, drug memories and anti-relapse treatments

(2012) Amy L. Milton et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why?

(2012) Marina E. Wolf et al.   Frontiers in Molecular Neuroscience

Emergence of context-associated GluR1 and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration

(2011) Scott Edwards et al.   ADDICTION BIOLOGY

Group I mGluR Activation Reverses Cocaine-Induced Accumulation of Calcium-Permeable AMPA Receptors in Nucleus Accumbens Synapses via a Protein Kinase C-Dependent Mechanism

(2011) J. E. McCutcheon et al.   JOURNAL OF NEUROSCIENCE

Calcium-Permeable AMPA Receptors Are Present in Nucleus Accumbens Synapses after Prolonged Withdrawal from Cocaine Self-Administration But Not Experimenter-Administered Cocaine

(2011) J. E. McCutcheon et al.   JOURNAL OF NEUROSCIENCE

Cocaine Withdrawal Impairs Metabotropic Glutamate Receptor-Dependent Long-Term Depression in the Nucleus Accumbens

(2011) C.-C. Huang et al.   JOURNAL OF NEUROSCIENCE

In utero exposure to cocaine delays postnatal synaptic maturation of glutamatergic transmission in the VTA

(2011) Camilla Bellone et al.   NATURE NEUROSCIENCE

Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy

(2011) R.T. Ngomba et al.   NEUROPHARMACOLOGY

Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca2+-permeable AMPA receptors during the incubation of cocaine craving

(2011) Carrie R. Ferrario et al.   NEUROPHARMACOLOGY

Glutamatergic medications for the treatment of drug and behavioral addictions

(2011) M. Foster Olive et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Neurobiology of the incubation of drug craving

(2011) Charles L. Pickens et al.   TRENDS IN NEUROSCIENCES

Quantitative analysis of AMPA receptor subunit composition in addiction-related brain regions

(2010) Jeremy M. Reimers et al.   BRAIN RESEARCH

Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction

(2010) M. Foster Olive   EUROPEAN JOURNAL OF PHARMACOLOGY

Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens

(2010) Brad A Grueter et al.   NATURE NEUROSCIENCE

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Calcium-Permeable AMPA Receptor Dynamics Mediate Fear Memory Erasure

(2010) R. L. Clem et al.   SCIENCE

Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies

(2009) Matthias Klugmann et al.   BEHAVIOURAL PHARMACOLOGY

Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers

(2009) Eric Vieira et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Acetylcysteine reverses cocaine-induced metaplasticity

(2009) Khaled Moussawi et al.   NATURE NEUROSCIENCE

Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc

(2009) Manuel Mameli et al.   NATURE NEUROSCIENCE

Synaptic mGluR activation drives plasticity of calcium-permeable AMPA receptors

(2009) Leah Kelly et al.   NATURE NEUROSCIENCE

The glutamate homeostasis hypothesis of addiction

(2009) Peter W. Kalivas   NATURE REVIEWS NEUROSCIENCE

Cortico-Basal Ganglia Reward Network: Microcircuitry

(2009) Susan R Sesack et al.   NEUROPSYCHOPHARMACOLOGY

Extended daily access to cocaine results in distinct alterations in Homer 1b/c and NMDA receptor subunit expression within the medial prefrontal cortex

(2009) Osnat Ben-Shahar et al.   SYNAPSE

Mechanism and Time Course of Cocaine-Induced Long-Term Potentiation in the Ventral Tegmental Area

(2008) E. Argilli et al.   JOURNAL OF NEUROSCIENCE

Endogenous Homer Proteins Regulate Metabotropic Glutamate Receptor Signaling in Neurons

(2008) P. J. Kammermeier   JOURNAL OF NEUROSCIENCE

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

(2008) Kelly L. Conrad et al.   NATURE

Homers regulate drug-induced neuroplasticity: Implications for addiction

(2007) Karen K. Szumlinski et al.   BIOCHEMICAL PHARMACOLOGY