Stress and VTA synapses: implications for addiction and depression

Kappa Opioid Receptor-Mediated Dysregulation of Gamma-Aminobutyric Acidergic Transmission in the Central Amygdala in Cocaine Addiction

(2013) Marsida Kallupi et al.   BIOLOGICAL PSYCHIATRY

Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area

(2013) Kelly A. Butts et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Current Status of Ketamine and Related Compounds for Depression

(2013) Daniel C. Mathews et al.   JOURNAL OF CLINICAL PSYCHIATRY

Hypothalamic Neurotensin Projections Promote Reward by Enhancing Glutamate Transmission in the VTA

(2013) K. A. Kempadoo et al.   JOURNAL OF NEUROSCIENCE

Dopamine Triggers Heterosynaptic Plasticity

(2013) M. Ishikawa et al.   JOURNAL OF NEUROSCIENCE

Opioid Modulation of Ventral Pallidal Afferents to Ventral Tegmental Area Neurons

(2013) G. O. Hjelmstad et al.   JOURNAL OF NEUROSCIENCE

Exposure to cocaine regulates inhibitory synaptic transmission from the ventral tegmental area to the nucleus accumbens

(2013) Masago Ishikawa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Distinct extended amygdala circuits for divergent motivational states

(2013) Joshua H. Jennings et al.   NATURE

Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving

(2013) Jessica A Loweth et al.   NATURE NEUROSCIENCE

A Unique Population of Ventral Tegmental Area Neurons Inhibits the Lateral Habenula to Promote Reward

(2013) Alice M. Stamatakis et al.   NEURON

Expression of Cocaine-Evoked Synaptic Plasticity by GluN3A-Containing NMDA Receptors

(2013) Tifei Yuan et al.   NEURON

Kappa Opioid Receptors Regulate Stress-Induced Cocaine Seeking and Synaptic Plasticity

(2013) Nicholas M. Graziane et al.   NEURON

Reward and aversion in a heterogeneous midbrain dopamine system

(2013) Stephan Lammel et al.   NEUROPHARMACOLOGY

Ablation of Kappa-Opioid Receptors from Brain Dopamine Neurons has Anxiolytic-Like Effects and Enhances Cocaine-Induced Plasticity

(2013) Ashlee Van't Veer et al.   NEUROPSYCHOPHARMACOLOGY

Role of kappa-opioid receptors in stress and anxiety-related behavior

(2013) Ashlee Van’t Veer et al.   PSYCHOPHARMACOLOGY

Cocaine Disinhibits Dopamine Neurons by Potentiation of GABA Transmission in the Ventral Tegmental Area

(2013) C. Bocklisch et al.   SCIENCE

Ventral Tegmental Area Glutamate Neurons: Electrophysiological Properties and Projections

(2012) T. S. Hnasko et al.   JOURNAL OF NEUROSCIENCE

Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning

(2012) Matthew T. C. Brown et al.   NATURE

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA

(2012) Nicolas X. Tritsch et al.   NATURE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

(2012) Kay M. Tye et al.   NATURE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

Neurobiology of resilience

(2012) Scott J Russo et al.   NATURE NEUROSCIENCE

Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance

(2012) Alice M Stamatakis et al.   NATURE NEUROSCIENCE

Activation of VTA GABA Neurons Disrupts Reward Consumption

(2012) Ruud van Zessen et al.   NEURON

GABA Neurons of the VTA Drive Conditioned Place Aversion

(2012) Kelly R. Tan et al.   NEURON

Effects of the Circadian Rhythm Gene Period 1 (Per1) on Psychosocial Stress-Induced Alcohol Drinking

(2011) Li Dong et al.   AMERICAN JOURNAL OF PSYCHIATRY

Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat

(2011) Luciano Gonçalves et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Nucleus Accumbens Medium Spiny Neurons Target Non-Dopaminergic Neurons in the Ventral Tegmental Area

(2011) Y. Xia et al.   JOURNAL OF NEUROSCIENCE

A novel δ opioid receptor-mediated enhancement of GABAAreceptor function induced by stress in ventral tegmental area neurons

(2011) Elyssa B. Margolis et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synaptic potentiation onto habenula neurons in the learned helplessness model of depression

(2011) Bo Li et al.   NATURE

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area

(2011) Manuel Mameli et al.   NATURE NEUROSCIENCE

From glutamate co-release to vesicular synergy: vesicular glutamate transporters

(2011) Salah El Mestikawy et al.   NATURE REVIEWS NEUROSCIENCE

Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli

(2011) Stephan Lammel et al.   NEURON

Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement

(2011) Ilana B. Witten et al.   NEURON

Drug-Evoked Synaptic Plasticity in Addiction: From Molecular Changes to Circuit Remodeling

(2011) Christian Lüscher et al.   NEURON

Effects of stress on alcohol drinking: a review of animal studies

(2011) Howard C. Becker et al.   PSYCHOPHARMACOLOGY

Increased phasic activity of VTA dopamine neurons in mice 3 weeks after repeated social defeat

(2010) Maria Razzoli et al.   BEHAVIOURAL BRAIN RESEARCH

Persistent Increases in Cocaine-Seeking Behavior After Acute Exposure to Cold Swim Stress

(2010) Kelly L. Conrad et al.   BIOLOGICAL PSYCHIATRY

Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area

(2010) Jason L. Niehaus et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate

(2010) G. D. Stuber et al.   JOURNAL OF NEUROSCIENCE

Ventral Tegmental Afferents in Stress-Induced Reinstatement: The Role of cAMP Response Element-Binding Protein

(2010) L. A. Briand et al.   JOURNAL OF NEUROSCIENCE

Mesolimbic Dopamine Neurons in the Brain Reward Circuit Mediate Susceptibility to Social Defeat and Antidepressant Action

(2010) J.-L. Cao et al.   JOURNAL OF NEUROSCIENCE

Effects of stress and aversion on dopamine neurons: Implications for addiction

(2010) Mark A. Ungless et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats

(2010) Patrick M. Beardsley et al.   PSYCHOPHARMACOLOGY

Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration

(2010) Robin E. Sperling et al.   PSYCHOPHARMACOLOGY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Chronic Stress, Drug Use, and Vulnerability to Addiction

(2009) Rajita Sinha   Annals of the New York Academy of Sciences

Remission of Major Depression Under Deep Brain Stimulation of the Lateral Habenula in a Therapy-Refractory Patient

(2009) Alexander Sartorius et al.   BIOLOGICAL PSYCHIATRY

A ventral tegmental CRF–glutamate–dopamine interaction in addiction

(2009) Roy A. Wise et al.   BRAIN RESEARCH

The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors

(2009) M.R. Bruchas et al.   BRAIN RESEARCH

Chronic Cocaine Enhances Corticotropin-Releasing Factor-Dependent Potentiation of Excitatory Transmission in Ventral Tegmental Area Dopamine Neurons

(2009) J. Hahn et al.   JOURNAL OF NEUROSCIENCE

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking

(2009) Frédéric Ambroggi et al.   NATURE NEUROSCIENCE

PKG and PKA Signaling in LTP at GABAergic Synapses

(2009) Fereshteh S Nugent et al.   NEUROPSYCHOPHARMACOLOGY

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Cortico-Basal Ganglia Reward Network: Microcircuitry

(2009) Susan R Sesack et al.   NEUROPSYCHOPHARMACOLOGY

Stress-induced, glucocorticoid-dependent strengthening of glutamatergic synaptic transmission in midbrain dopamine neurons

(2009) Shabrine S. Daftary et al.   NEUROSCIENCE LETTERS

Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

(2009) Benjamin B. Land et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli

(2009) F. Brischoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroanatomical characterization of endogenous opioids in the bed nucleus of the stria terminalis

(2009) Jean-François Poulin et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine

(2009) Sunmee Wee et al.   PSYCHOPHARMACOLOGY

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Mechanism and Time Course of Cocaine-Induced Long-Term Potentiation in the Ventral Tegmental Area

(2008) E. Argilli et al.   JOURNAL OF NEUROSCIENCE

The Dysphoric Component of Stress Is Encoded by Activation of the Dynorphin  -Opioid System

(2008) B. B. Land et al.   JOURNAL OF NEUROSCIENCE

Midbrain Dopamine Neurons: Projection Target Determines Action Potential Duration and Dopamine D2 Receptor Inhibition

(2008) E. B. Margolis et al.   JOURNAL OF NEUROSCIENCE

Corticotropin-releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C-dependent enhancement ofIh

(2008) M. J. Wanat et al.   JOURNAL OF PHYSIOLOGY-LONDON

Desipramine Reduces Stress-Activated Dynorphin Expression and CREB Phosphorylation in NAc Tissue

(2008) E. H. Chartoff et al.   MOLECULAR PHARMACOLOGY

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

(2008) Kelly L. Conrad et al.   NATURE

Cocaine but Not Natural Reward Self-Administration nor Passive Cocaine Infusion Produces Persistent LTP in the VTA

(2008) Billy T. Chen et al.   NEURON

Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System

(2008) Stephan Lammel et al.   NEURON

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

(2008) R.G. Nair-Roberts et al.   NEUROSCIENCE

Social stress, therapeutics and drug abuse: Preclinical models of escalated and depressed intake

(2008) K MICZEK et al.   PHARMACOLOGY & THERAPEUTICS

Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

(2008) Van A. Redila et al.   PSYCHOPHARMACOLOGY