Phenyl-γ-valerolactones, flavan-3-ol colonic metabolites, protect brown adipocytes from oxidative stress without affecting their differentiation or function

Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species

(2016) L. Rebiger et al.   BIOSCIENCE REPORTS

Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues

(2016) Vanessa Pellegrinelli et al.   DIABETOLOGIA

A single oral dose of flavan-3-ols enhances energy expenditure by sympathetic nerve stimulation in mice

(2016) Naoya Kamio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory actions of (−)-epicatechin in the adipose tissue of obese mice

(2016) Ahmed Bettaieb et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cranberry (poly)phenol metabolites correlate with improvements in vascular function: A double-blind, randomized, controlled, dose-response, crossover study

(2016) Ana Rodriguez-Mateos et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Plasma and Urinary Phenolic Profiles after Acute and Repetitive Intake of Wild Blueberry

(2016) Rodrigo Feliciano et al.   MOLECULES

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

(2016) Edward T. Chouchani et al.   NATURE

New therapeutic approaches for the treatment of obesity

(2016) Alan R. Saltiel   Science Translational Medicine

The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety and mechanisms of action of polyphenolic bioactives

(2016) Javier I. Ottaviani et al.   Scientific Reports

Catalytic, Enantioselective Vinylogous Mukaiyama Aldol Reaction of Furan-Based Dienoxy Silanes: A Chemodivergent Approach to γ-Valerolactone Flavan-3-ol Metabolites and δ-Lactone Analogues

(2015) Claudio Curti et al.   ADVANCED SYNTHESIS & CATALYSIS

Green tea extract activates AMPK and ameliorates white adipose tissue metabolic dysfunction induced by obesity

(2015) Andréa Rocha et al.   EUROPEAN JOURNAL OF NUTRITION

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

Diet-induced obesity causes insulin resistance in mouse brown adipose tissue

(2015) Carla Roberts-Toler et al.   Obesity

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

(2014) Limei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Effects of (−)-epicatechin on a diet-induced rat model of cardiometabolic risk factors

(2014) Gabriel Gutiérrez-Salmeán et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

(−)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress

(2014) Ahmed Bettaieb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Flavan-3-ol fraction from cocoa powder promotes mitochondrial biogenesis in skeletal muscle in mice

(2014) Naoki Watanabe et al.   Lipids in Health and Disease

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

Enhancement of Energy Expenditure following a Single Oral Dose of Flavan-3-Ols Associated with an Increase in Catecholamine Secretion

(2014) Yusuke Matsumura et al.   PLoS One

Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols

(2013) Michael N Clifford et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lipodystrophy-Linked LMNA p.R482W Mutation Induces Clinical Early Atherosclerosis and In Vitro Endothelial Dysfunction

(2013) Guillaume Bidault et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dietary cocoa ameliorates obesity-related inflammation in high fat-fed mice

(2013) Yeyi Gu et al.   EUROPEAN JOURNAL OF NUTRITION

Modulation of metabolic syndrome-related inflammation by cocoa

(2013) Yeyi Gu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

(2012) Daniele Del Rio et al.   ANTIOXIDANTS & REDOX SIGNALING

Prevention mechanisms of glucose intolerance and obesity by cacao liquor procyanidin extract in high-fat diet-fed C57BL/6 mice

(2012) Yoko Yamashita et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effects of green tea extracts on non-shivering thermogenesis during mild cold exposure in young men

(2012) Chantal Gosselin et al.   BRITISH JOURNAL OF NUTRITION

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol)

(2012) Klaus Uhlenhut et al.   FREE RADICAL BIOLOGY AND MEDICINE

Low doses of grape seed procyanidins reduce adiposity and improve the plasma lipid profile in hamsters

(2012) A Caimari et al.   INTERNATIONAL JOURNAL OF OBESITY

Flavonoid-Rich Cocoa Consumption Affects Multiple Cardiovascular Risk Factors in a Meta-Analysis of Short-Term Studies

(2011) Mark G. Shrime et al.   JOURNAL OF NUTRITION

The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials

(2011) Harm H.H. Feringa et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Bioavailability and catabolism of green tea flavan-3-ols in humans

(2010) Daniele Del Rio et al.   NUTRITION

Procyanidin Dimers Are Metabolized by Human Microbiota with 2-(3,4-Dihydroxyphenyl)acetic Acid and 5-(3,4-Dihydroxyphenyl)-γ-valerolactone as the Major Metabolites

(2009) Maaike M. Appeldoorn et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tea catechins enhance the mRNA expression of uncoupling protein 1 in rat brown adipose tissue

(2008) Sachiko Nomura et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chardonnay grape seed procyanidin extract supplementation prevents high-fat diet-induced obesity in hamsters by improving adipokine imbalance and oxidative stress markers

(2008) Kelly Décordé et al.   MOLECULAR NUTRITION & FOOD RESEARCH