Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues

Peroxisome Proliferator-Activated Receptor-γ: Master Regulator of Adipogenesis and Obesity

(2016) Xiaoru Shao et al.   Current Stem Cell Research & Therapy

Inflammatory characteristics of distinct abdominal adipose tissue depots relate differently to metabolic risk factors for cardiovascular disease

(2015) Mariëtte E.G. Kranendonk et al.   ATHEROSCLEROSIS

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis

(2015) Mikael Rydén et al.   Cell Metabolism

Browning of Subcutaneous White Adipose Tissue in Humans after Severe Adrenergic Stress

(2015) Labros S. Sidossis et al.   Cell Metabolism

Perilipin+embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion

(2015) Ki Yong Hong et al.   DEVELOPMENT

BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis

(2015) Birgit Gustafson et al.   DIABETES

Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice

(2015) Samantha L. Hocking et al.   DIABETOLOGIA

The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice

(2015) Lianne van Beek et al.   DIABETOLOGIA

COL6A3 Is Regulated by Leptin in Human Adipose Tissue and Reduced in Obesity

(2015) Laura J. McCulloch et al.   ENDOCRINOLOGY

Cellular origins of cold-induced brown adipocytes in adult mice

(2015) Yun-Hee Lee et al.   FASEB JOURNAL

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

(2015) Tomoaki Iwayama et al.   GENES & DEVELOPMENT

Adipose tissue fatty acid storage factors: effects of depot, sex and fat cell size

(2015) K C Hames et al.   INTERNATIONAL JOURNAL OF OBESITY

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

(2015) Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation

(2015) Qiong A. Wang et al.   NATURE CELL BIOLOGY

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

(2015) Elise Dalmas et al.   NATURE MEDICINE

Diet-induced obesity causes insulin resistance in mouse brown adipose tissue

(2015) Carla Roberts-Toler et al.   Obesity

Human White and Brite Adipogenesis is Supported by MSCA1 and is Impaired by Immune Cells

(2015) David Estève et al.   STEM CELLS

Insulin resistance and impaired adipogenesis

(2015) Birgit Gustafson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

CILAIR-Based Secretome Analysis of Obese Visceral and Subcutaneous Adipose Tissues Reveals Distinctive ECM Remodeling and Inflammation Mediators

(2015) Arturo Roca-Rivada et al.   Scientific Reports

Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre

(2015) Joan Sanchez-Gurmaches et al.   Stem Cell Reports

The cell size and distribution of adipocytes from subcutaneous and visceral fat is associated with type 2 diabetes mellitus in humans

(2015) Lingling Fang et al.   Adipocyte

Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation

(2014) G. Andres Contreras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice

(2014) Meritxell Rosell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

BMP-9 as a potent brown adipogenic inducer with anti-obesity capacity

(2014) Mario Meng-Chiang Kuo et al.   BIOMATERIALS

Loss of White Adipose Hyperplastic Potential Is Associated with Enhanced Susceptibility to Insulin Resistance

(2014) Soo M. Kim et al.   Cell Metabolism

Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling

(2014) Ingrid Wernstedt Asterholm et al.   Cell Metabolism

The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β

(2014) Clarissa S. Craft et al.   DIABETES

Characteristic Expression of Extracellular Matrix in Subcutaneous Adipose Tissue Development and Adipogenesis; Comparison with Visceral Adipose Tissue

(2014) Shinobu Mori et al.   International Journal of Biological Sciences

Association of Adipose Tissue and Liver Fibrosis With Tissue Stiffness in Morbid Obesity: Links With Diabetes and BMI Loss After Gastric Bypass

(2014) Meriem Abdennour et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Human adipocyte function is impacted by mechanical cues

(2014) V Pellegrinelli et al.   JOURNAL OF PATHOLOGY

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

(2014) You-Ying Chau et al.   NATURE CELL BIOLOGY

The role of BMPs in endothelial cell function and dysfunction

(2014) Laura A. Dyer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed

(2014) Joan Sanchez-Gurmaches et al.   Nature Communications

Low abdominal subcutaneous preadipocyte adipogenesis is associated with visceral obesity, visceral adipocyte hypertrophy, and a dysmetabolic state

(2014) Julie Lessard et al.   Adipocyte

Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes

(2013) Tomoya Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Macrophage elastase (MMP-12) in expanding murine adipose tissue

(2013) D. Bauters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Adipocyte lineages: Tracing back the origins of fat

(2013) Joan Sanchez-Gurmaches et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Angiogenesis and Vascular Functions in Modulation of Obesity, Adipose Metabolism, and Insulin Sensitivity

(2013) Yihai Cao   Cell Metabolism

Fibrosis and Adipose Tissue Dysfunction

(2013) Kai Sun et al.   Cell Metabolism

Bmp4 expressed in preadipocytes is required for the onset of adipocyte differentiation

(2013) Masashi Suenaga et al.   CYTOKINE

Vascular endothelial growth factor is important for brown adipose tissue development and maintenance

(2013) Mandrita Bagchi et al.   FASEB JOURNAL

A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes

(2013) W. Liu et al.   JOURNAL OF CELL SCIENCE

Variations in the Size of the Major Omentum Are Primarily Determined by Fat Cell Number

(2013) Peter Arner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

Bi-directional interconversion of brite and white adipocytes

(2013) Matthias Rosenwald et al.   NATURE CELL BIOLOGY

Characterization of the adipocyte cellular lineage in vivo

(2013) Ryan Berry et al.   NATURE CELL BIOLOGY

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

Fat cell size and adipokine expression in relation to gender, depot, and metabolic risk factors in morbidly obese adolescents

(2013) Yiying Zhang et al.   Obesity

Adipose tissue depot and cell size dependency of adiponectin synthesis and secretion in human obesity

(2013) Lauren K Meyer et al.   Adipocyte

Structural and biochemical characteristics of various white adipose tissue depots

(2012) A. Wronska et al.   Acta Physiologica

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells

(2012) Rana K. Gupta et al.   Cell Metabolism

PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors

(2012) Joan Sanchez-Gurmaches et al.   Cell Metabolism

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

The Vascular Endothelium of the Adipose Tissue Gives Rise to Both White and Brown Fat Cells

(2012) Khanh-Van Tran et al.   Cell Metabolism

Intrinsic Differences in Adipocyte Precursor Cells From Different White Fat Depots

(2012) Y. Macotela et al.   DIABETES

Fatty acid binding protein 4 expression marks a population of adipocyte progenitors in white and brown adipose tissues

(2012) Tizhong Shan et al.   FASEB JOURNAL

Apelin inhibits adipogenesis and lipolysis through distinct molecular pathways

(2012) Aung Than et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation

(2011) Timothy P. Fitzgibbons et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

(2011) Olga Gealekman et al.   CIRCULATION

The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function

(2011) M. E. Lidell et al.   DIABETES

Immune cells in adipose tissue: Key players in metabolic disorders

(2011) K. Lolmède et al.   DIABETES & METABOLISM

Removal of intra-abdominal visceral adipose tissue improves glucose tolerance in rats: Role of hepatic triglyceride storage

(2011) Michelle T. Foster et al.   PHYSIOLOGY & BEHAVIOR

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

(2010) Michael Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipocyte extracellular matrix composition, dynamics and role in obesity

(2010) Edwin C. M. Mariman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Adipose Tissue Endothelial Cells From Obese Human Subjects: Differences Among Depots in Angiogenic, Metabolic, and Inflammatory Gene Expression and Cellular Senescence

(2010) A. Villaret et al.   DIABETES

Subcutaneous adipose tissue classification

(2010) A. Sbarbati et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells

(2010) Christoph Lepper et al.   GENESIS

Adipose angiogenesis: quantitative methods to study microvessel growth, regression and remodeling in vivo

(2010) Yuan Xue et al.   Nature Protocols

Sex- and Depot-Dependent Differences in Adipogenesis in Normal-Weight Humans

(2010) Yourka D. Tchoukalova et al.   Obesity

De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific

(2010) S. M. Majka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

(2010) T. J. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transdifferentiation properties of adipocytes in the adipose organ

(2009) Saverio Cinti   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

(2009) E. Arner et al.   DIABETES

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose Tissue Collagen VI in Obesity

(2009) Magdalena Pasarica et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subcutaneous and visceral adipose tissue: structural and functional differences

(2009) M. Mohsen Ibrahim   Obesity Reviews

BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

(2009) H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes

(2009) Christian Elabd et al.   STEM CELLS

Depot-Specific Differences in Adipogenic Progenitor Abundance and Proliferative Response to High-Fat Diet

(2009) Aaron W.B. Joe et al.   STEM CELLS

Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production

(2008) Olga Gealekman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ

(2008) I. Murano et al.   JOURNAL OF ANATOMY

Role of Body Fat Distribution and the Metabolic Complications of Obesity

(2008) Michael D. Jensen   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

(2008) T. Khan et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE