Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

(2017) Roni Levin et al.   MOLECULAR BIOLOGY OF THE CELL

Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model

(2017) Maria B. Bagh et al.   Nature Communications

Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency

(2016) Lauren M. Compton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes

(2016) Gina A. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

(2016) Mohammad T. Mazhab-Jafari et al.   NATURE

Detection and manipulation of phosphoinositides

(2015) Olof Idevall-Hagren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphoinositides regulate ion channels

(2015) Bertil Hille et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Affinity Purification and Structural Features of the Yeast Vacuolar ATPase VoMembrane Sector

(2015) Sergio Couoh-Cardel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Dynamic Membrane Recognition by trans-Golgi Network Specific FAPP Proteins

(2015) Marc Lenoir et al.   JOURNAL OF MOLECULAR BIOLOGY

Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase

(2015) Jianhua Zhao et al.   NATURE

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

(2015) Xi Luo et al.   PLoS Pathogens

The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase

(2014) Sheena Claire Li et al.   MOLECULAR BIOLOGY OF THE CELL

Qualitative and quantitative characterization of protein-phosphoinositide interactions with liposome-based methods

(2013) Ricarda A. Busse et al.   Autophagy

The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2

(2013) Hiroyuki Hosokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Rational Identification of Enoxacin as a Novel V-ATPase-Directed Osteoclast Inhibitor

(2012) Edgardo J. Toro et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Further characterization of ATP6V0A2-related autosomal recessive cutis laxa

(2012) Björn Fischer et al.   HUMAN GENETICS

Subunit Interactions at the V1-VoInterface in Yeast Vacuolar ATPase

(2012) Rebecca A. Oot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sorting of the Yeast Vacuolar-type, Proton-translocating ATPase Enzyme Complex (V-ATPase)

(2012) Gregory C. Finnigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

(2012) Sulochanadevi Baskaran et al.   MOLECULAR CELL

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P

(2012) S. N. Zolov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoinositide isoforms determine compartment-specific ion channel activity

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimized protocols and plasmids for in vivo cloning in yeast

(2011) Ana A. Kitazono   GENE

Crystal Structure of the Cytoplasmic N-Terminal Domain of Subunit I, a Homolog of Subunit a, of V-ATPase

(2011) Sankaranarayanan Srinivasan et al.   JOURNAL OF MOLECULAR BIOLOGY

The reconstructed ancestral subunit a functions as both V-ATPase isoforms Vph1p and Stv1p in Saccharomyces cerevisiae

(2011) Gregory C. Finnigan et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

(2011) Scott B. Hansen et al.   NATURE

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Genome-Wide Analysis Reveals the Vacuolar pH-Stat of Saccharomyces cerevisiae

(2011) Christopher L. Brett et al.   PLoS One

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Phosphatidylinositol-3,5-Bisphosphate: No Longer the Poor PIP2

(2011) Cheuk Y. Ho et al.   TRAFFIC

Inhibitors of V-ATPases: old and new players

(2009) M. Huss et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Sensors and regulators of intracellular pH

(2009) Joseph R. Casey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

(2008) Natsuko Jin et al.   EMBO JOURNAL

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

(2008) G. D'Angelo et al.   JOURNAL OF CELL SCIENCE

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY