Cytotoxic activity in cutaneous leishmaniasis

CD3+CD4negCD8neg (double negative) T lymphocytes and NKT cells as the main cytotoxic-related-CD107a+ cells in lesions of cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis

(2017) Raquel Ferraz et al.   Parasites & Vectors

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

(2017) Fernanda O. Novais et al.   PLoS Pathogens

Apoptosis and frequency of total and effector CD8+ T lymphocytes from cutaneous leishmaniasis patients during antimonial therapy

(2015) Raquel Ferraz et al.   BMC INFECTIOUS DISEASES

Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+T Cells That Exacerbates Disease in Mice Coinfected withLeishmania major

(2015) Erika J. Crosby et al.   JOURNAL OF IMMUNOLOGY

Genomic Profiling of Human Leishmania braziliensis Lesions Identifies Transcriptional Modules Associated with Cutaneous Immunopathology

(2015) Fernanda O. Novais et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Proteome Profiling of Human Cutaneous Leishmaniasis Lesion

(2015) Claire da Silva Santos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Exposure to Leishmania braziliensis Triggers Neutrophil Activation and Apoptosis

(2015) Sarah A. C. Falcão et al.   PLoS Neglected Tropical Diseases

Protective and Pathological Functions of CD8+T Cells in Leishmania braziliensis Infection

(2014) Thiago Marconi Cardoso et al.   INFECTION AND IMMUNITY

Involvement of Different CD4+T Cell Subsets Producing Granzyme B in the Immune Response toLeishmania majorAntigens

(2014) Ikbel Naouar et al.   MEDIATORS OF INFLAMMATION

CD8+ T cells in situ in different clinical forms of human cutaneous leishmaniasis

(2014) Marina Loyola Dantas et al.   Revista da Sociedade Brasileira de Medicina Tropical

Elucidating Sources and Roles of Granzymes A and B during Bacterial Infection and Sepsis

(2014) Maykel A. Arias et al.   Cell Reports

Matrix Metalloproteinase 9 Production by Monocytes is Enhanced by TNF and Participates in the Pathology of Human Cutaneous Leishmaniasis

(2014) Taís M. Campos et al.   PLoS Neglected Tropical Diseases

Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

(2014) Erika J. Crosby et al.   PLoS Pathogens

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

(2013) Fernanda O. Novais et al.   PLoS Pathogens

Granzyme B in injury, inflammation, and repair

(2012) Paul R. Hiebert et al.   TRENDS IN MOLECULAR MEDICINE

MMP-9 activity is induced by Leishmania braziliensis infection and correlates with mucosal leishmaniasis

(2011) Ana Cláudia Maretti-Mira et al.   ACTA TROPICA

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

(2011) Inna S. Afonina et al.   MOLECULAR CELL

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

(2011) Jerome Thiery et al.   NATURE IMMUNOLOGY

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

The interplay between Leishmania promastigotes and human Natural Killer cells in vitro leads to direct lysis of Leishmania by NK cells and modulation of NK cell activity by Leishmania promastigotes

(2011) THORSTEN LIEKE et al.   PARASITOLOGY

Therapeutic failure in American cutaneous leishmaniasis is associated with gelatinase activity and cytokine expression

(2010) A. C. Maretti-Mira et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Regulation of CD8+ T cell responses to infection with parasitic protozoa

(2010) Kimberly A. Jordan et al.   EXPERIMENTAL PARASITOLOGY

Leukocytes Infiltrate the Skin and Draining Lymph Nodes in Response to the ProtozoanLeishmania infantum chagasi

(2010) Colin J. Thalhofer et al.   INFECTION AND IMMUNITY

Granzyme B is a novel interleukin-18 converting enzyme

(2010) Youichi Omoto et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-γ production

(2009) Lúcio Roberto Castellano et al.   HUMAN IMMUNOLOGY

Neutrophils and Macrophages Cooperate in Host Resistance against Leishmania braziliensis Infection

(2009) F. O. Novais et al.   JOURNAL OF IMMUNOLOGY

The battlefield of perforin/granzyme cell death pathways

(2009) Sabine Hoves et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Recruitment of CD8+T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis

(2009) D. R. FARIA et al.   PARASITE IMMUNOLOGY

In vitro evidence for metallopeptidase participation in hepatocyte damage induced by Leishmania chagasi-infected macrophages

(2008) Juliana Dias Costa et al.   ACTA TROPICA

Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation

(2008) T. Lieke et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response

(2008) Sunil S. Metkar et al.   IMMUNITY

Three matrix metalloproteinases are required in vivo for macrophage migration during embryonic development

(2008) Matthew L. Tomlinson et al.   MECHANISMS OF DEVELOPMENT

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE