Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

Granzyme A activates another way to die

(2015) Judy Lieberman   IMMUNOLOGICAL REVIEWS

Orphan granzymes find a home

(2015) Niels Bovenschen et al.   IMMUNOLOGICAL REVIEWS

Cytotoxic immunological synapses

(2010) Michael L. Dustin et al.   IMMUNOLOGICAL REVIEWS

Functional dissection of the granzyme family: cell death and inflammation

(2010) Desiree A. Anthony et al.   IMMUNOLOGICAL REVIEWS

Human Perforin Employs Different Avenues to Damage Membranes

(2010) Tilen Praper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH

(2010) Tilen Praper et al.   MOLECULAR IMMUNOLOGY

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

(2009) J. Thiery et al.   BLOOD

The Molecular Basis for Perforin Oligomerization and Transmembrane Pore Assembly

(2009) Katherine Baran et al.   IMMUNITY

Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis

(2008) Matthias Husmann et al.   FEBS LETTERS

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

(2008) Vincent Idone et al.   JOURNAL OF CELL BIOLOGY