The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role
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Title
The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role
Authors
Keywords
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Journal
MEDICINAL RESEARCH REVIEWS
Volume 38, Issue 4, Pages 1235-1254
Publisher
Wiley
Online
2017-09-19
DOI
10.1002/med.21473
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Note: Only part of the references are listed.- The role of stromal cancer-associated fibroblasts in pancreatic cancer
- (2017) Dagny von Ahrens et al. Journal of Hematology & Oncology
- Epidemiology of ovarian cancer: a review
- (2017) Reid Brett M. et al. Cancer Biology & Medicine
- Autophagy-Regulating microRNAs and Cancer
- (2017) Devrim Gozuacik et al. Frontiers in Oncology
- The Unique Molecular and Cellular Microenvironment of Ovarian Cancer
- (2017) Thomas Worzfeld et al. Frontiers in Oncology
- Therapeutic strategies for targeting the ovarian tumor stroma
- (2017) Song Yi Ko et al. World Journal of Clinical Cases
- The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14
- (2016) Ji-Man Park et al. Autophagy
- Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling
- (2016) Huan Yan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cancer treatment and survivorship statistics, 2016
- (2016) Kimberly D. Miller et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Stress management by autophagy: Implications for chemoresistance
- (2016) Zhao Huang et al. INTERNATIONAL JOURNAL OF CANCER
- Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment
- (2016) Veronica Rojas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy
- (2016) Alessandra Ferraresi et al. MOLECULAR CARCINOGENESIS
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Autophagy as an emerging therapy target for ovarian carcinoma
- (2016) Lei Zhan et al. Oncotarget
- Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus
- (2016) Ji Hee Ha et al. Oncotarget
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
- (2016) Hongyun Zhao et al. eLife
- Pathophysiological Basis for the Formation of the Tumor Microenvironment
- (2016) Michael R. Horsman et al. Frontiers in Oncology
- Regulatory T cells, inherited variation, and clinical outcome in epithelial ovarian cancer
- (2015) Keith L. Knutson et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix
- (2015) Jeremy D. Ward et al. CANCER LETTERS
- Autophagy and cell reprogramming
- (2015) Shuo Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Autophagy in malignant transformation and cancer progression
- (2015) L. Galluzzi et al. EMBO JOURNAL
- Lysophosphatidic acid signaling in ovarian cancer
- (2015) Anna Jesionowska et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion
- (2015) Paola Maycotte et al. MOLECULAR CANCER RESEARCH
- Beclin 1 regulates growth factor receptor signaling in breast cancer
- (2015) R A Rohatgi et al. ONCOGENE
- Eaten alive: novel insights into autophagy from multicellular model systems
- (2015) Hong Zhang et al. TRENDS IN CELL BIOLOGY
- Macrophage-derived chemokine CCL22 and regulatory T cells in ovarian cancer patients
- (2015) I. Wertel et al. TUMOR BIOLOGY
- Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
- (2015) Pui-Mun Wong et al. Nature Communications
- Tumors: Wounds That Do Not Heal--Redux
- (2015) H. F. Dvorak Cancer Immunology Research
- Inflammation and ovarian cancer – current views
- (2015) Rafał Kisielewski et al. Ginekologia Polska
- Cancer associated fibroblasts in hematological malignancies
- (2015) Lizzia Raffaghello et al. Oncotarget
- Cancer-Associated Fibroblasts and Their Putative Role in Potentiating the Initiation and Development of Epithelial Ovarian Cancer
- (2015) Isaiah G. Schauer et al. NEOPLASIA
- Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF
- (2014) Monique Bernard et al. Autophagy
- Metabolic orchestration between cancer cells and tumor microenvironment as a co-evolutionary source of chemoresistance in ovarian cancer: A therapeutic implication
- (2014) Dong Hoon Suh et al. BIOCHEMICAL PHARMACOLOGY
- Measurements of adiposity as clinical biomarkers for first-line bevacizumab-based chemotherapy in epithelial ovarian cancer
- (2014) Katrina N. Slaughter et al. GYNECOLOGIC ONCOLOGY
- Identification of new ovulation-related genes in humans by comparing the transcriptome of granulosa cells before and after ovulation triggering in the same controlled ovarian stimulation cycle
- (2014) M.L. Wissing et al. HUMAN REPRODUCTION
- NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer
- (2014) Kate Lawrenson et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells
- (2014) YOUNG-AH SUH et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Organellophagy: Eliminating cellular building blocks via selective autophagy
- (2014) Koji Okamoto JOURNAL OF CELL BIOLOGY
- The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation
- (2014) Rui Chen et al. JOURNAL OF CELL BIOLOGY
- Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
- (2014) Ubaldo E. Martinez-Outschoorn et al. SEMINARS IN CANCER BIOLOGY
- mTOR and autophagy: A dynamic relationship governed by nutrients and energy
- (2014) E.A. Dunlop et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential
- (2014) Cecilia S. Leung et al. Nature Communications
- Ovulation and extra-ovarian origin of ovarian cancer
- (2014) Yang Yang-Hartwich et al. Scientific Reports
- Epigenetic Control of Autophagy by MicroRNAs in Ovarian Cancer
- (2014) Rossella Titone et al. Biomed Research International
- Single Amino Acid Arginine Deprivation Triggers Prosurvival Autophagic Response in Ovarian Carcinoma SKOV3
- (2014) Galyna Shuvayeva et al. Biomed Research International
- Recent Concepts of Ovarian Carcinogenesis: Type I and Type II
- (2014) Masafumi Koshiyama et al. Biomed Research International
- Expression and Clinical Significance of the Autophagy Proteins BECLIN 1 and LC3 in Ovarian Cancer
- (2014) Guido Valente et al. Biomed Research International
- The Role of the Tumor Stroma in Ovarian Cancer
- (2014) Ben Davidson et al. Frontiers in Oncology
- Heterotypic Cellular Interactions in the Ovarian Tumor Microenvironment: Biological Significance and Therapeutic Implications
- (2014) Honami Naora Frontiers in Oncology
- Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumors
- (2013) Jessie Yanxiang Guo et al. Autophagy
- The ULK1 complex
- (2013) Pui-Mun Wong et al. Autophagy
- Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance
- (2013) Wen Yue et al. Autophagy
- Cancer Associated Fibroblasts express pro-inflammatory factors in human breast and ovarian tumors
- (2013) Neta Erez et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition
- (2013) Benoît Thibault et al. CANCER AND METASTASIS REVIEWS
- Stromal–Epithelial Crosstalk Provides a Suitable Microenvironment for the Progression of Ovarian Cancer Cellsin Vitro
- (2013) Shilong Fu et al. CANCER INVESTIGATION
- Microenvironment and tumor cell plasticity: An easy way out
- (2013) Maria Letizia Taddei et al. CANCER LETTERS
- Mesenchymal CD44 Expression Contributes to the Acquisition of an Activated Fibroblast Phenotype via TWIST Activation in the Tumor Microenvironment
- (2013) E. L. Spaeth et al. CANCER RESEARCH
- TGF- Modulates Ovarian Cancer Invasion by Upregulating CAF-Derived Versican in the Tumor Microenvironment
- (2013) T.-L. Yeung et al. CANCER RESEARCH
- Autophagy-Mediated Tumor Promotion
- (2013) Jessie Yanxiang Guo et al. CELL
- Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and “fibroblast addiction” are new therapeutic targets for drug discovery
- (2013) Michael P. Lisanti et al. CELL CYCLE
- The machinery of macroautophagy
- (2013) Yuchen Feng et al. CELL RESEARCH
- Targeting Tumor Microenvironment with Silibinin: Promise and Potential for a Translational Cancer Chemopreventive Strategy
- (2013) Gagan Deep et al. CURRENT CANCER DRUG TARGETS
- Autophagy and thyroid carcinogenesis: genetic and epigenetic links
- (2013) Federica Morani et al. ENDOCRINE-RELATED CANCER
- Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma
- (2013) Tianjiao Lyu et al. Epigenetics
- Fibroblast activation protein-α promotes ovarian cancer cell proliferation and invasion via extracellular and intracellular signaling mechanisms
- (2013) WeiWei Yang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Tumor-associated fibroblast-conditioned medium promotes tumor cell proliferation and angiogenesis
- (2013) L.N. Xu et al. GENETICS AND MOLECULAR RESEARCH
- Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma
- (2013) K. Bahar-Shany et al. GYNECOLOGIC ONCOLOGY
- Involvement of autophagy in cervical, endometrial and ovarian cancer
- (2013) T. Orfanelli et al. INTERNATIONAL JOURNAL OF CANCER
- Angiogenesis-Related Pathways in the Pathogenesis of Ovarian Cancer
- (2013) Nikos Gavalas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts
- (2013) Tat-San Lau et al. JOURNAL OF PATHOLOGY
- ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
- (2013) Ryan C. Russell et al. NATURE CELL BIOLOGY
- Latest research and treatment of advanced-stage epithelial ovarian cancer
- (2013) Robert L. Coleman et al. Nature Reviews Clinical Oncology
- The return of the nucleus: transcriptional and epigenetic control of autophagy
- (2013) Jens Füllgrabe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment
- (2013) Y Kwon et al. ONCOGENE
- Decreased Expression of Beclin 1 Correlates Closely with Bcl-xL Expression and Poor Prognosis of Ovarian Carcinoma
- (2013) Huan-Xin Lin et al. PLoS One
- ‘Cancer associated fibroblasts’ – more than meets the eye
- (2013) Shalom Madar et al. TRENDS IN MOLECULAR MEDICINE
- Autophagy: shaping the tumor microenvironment and therapeutic response
- (2013) Hannelore Maes et al. TRENDS IN MOLECULAR MEDICINE
- Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma
- (2013) Loukia N. Lili et al. Biomed Research International
- AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway
- (2012) Rui Kang et al. Autophagy
- Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
- (2012) Jonathan W. Wojtkowiak et al. CANCER RESEARCH
- Hereditary ovarian cancer and two-compartment tumor metabolism
- (2012) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth
- (2012) Valentina Carito et al. CELL CYCLE
- Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
- (2012) Claudia Capparelli et al. CELL CYCLE
- Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
- (2012) Carmela Guido et al. CELL CYCLE
- Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells
- (2012) Yue Wang et al. CYTOKINE
- Inflammation and ovarian cancer
- (2012) Antonio Macciò et al. CYTOKINE
- Minireview: Human Ovarian Cancer: Biology, Current Management, and Paths to Personalizing Therapy
- (2012) Ignacio Romero et al. ENDOCRINOLOGY
- Autophagic tumor stroma: Mechanisms and roles in tumor growth and progression
- (2012) Xianda Zhao et al. INTERNATIONAL JOURNAL OF CANCER
- HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts
- (2012) Song Yi Ko et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor stroma as targets for cancer therapy
- (2012) Jing Zhang et al. PHARMACOLOGY & THERAPEUTICS
- The emerging role of CXC chemokines in epithelial ovarian cancer
- (2012) Adam Rainczuk et al. REPRODUCTION
- MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer
- (2012) A. K. Mitra et al. Cancer Discovery
- MicroRNAs Play a Big Role in Regulating Ovarian Cancer-Associated Fibroblasts and the Tumor Microenvironment
- (2012) J. Chou et al. Cancer Discovery
- Involvement of autophagy in ovarian cancer: a working hypothesis
- (2012) Claudia Peracchio et al. Journal of Ovarian Research
- Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis
- (2011) Stephanos Pavlides et al. ANTIOXIDANTS & REDOX SIGNALING
- Modulation of autophagic activity by extracellular pH
- (2011) Teng Xu et al. Autophagy
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- (2011) Paolo Cirri et al. CANCER AND METASTASIS REVIEWS
- Circulating Inflammation Markers and Risk of Epithelial Ovarian Cancer
- (2011) T. V. Clendenen et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
- (2011) Yuan Zhang et al. CANCER LETTERS
- A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
- (2011) H. Kulbe et al. CANCER RESEARCH
- Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness
- (2011) J. Cai et al. CARCINOGENESIS
- Cytokine production and inflammation drive autophagy in the tumor microenvironment
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response
- (2011) Johanneke Kleinnijenhuis et al. IMMUNOLOGY
- Stromal–epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment
- (2011) Ubaldo E. Martinez-Outschoorn et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs
- (2011) Robert R. Langley et al. INTERNATIONAL JOURNAL OF CANCER
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy in hypoxia protects cancer cells against apoptosis induced by nutrient deprivation through a beclin1-dependent way in hepatocellular carcinoma
- (2011) Jianrui Song et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- IL1α and IL4 signalling in human ovarian surface epithelial cells
- (2011) Georgia Papacleovoulou et al. JOURNAL OF ENDOCRINOLOGY
- Regulation of Tumor Angiogenesis by EZH2
- (2010) Chunhua Lu et al. CANCER CELL
- Identification of a Metalloprotease-Chemokine Signaling System in the Ovarian Cancer Microenvironment: Implications for Antiangiogenic Therapy
- (2010) A. Agarwal et al. CANCER RESEARCH
- CXCR2 Promotes Ovarian Cancer Growth through Dysregulated Cell Cycle, Diminished Apoptosis, and Enhanced Angiogenesis
- (2010) G. Yang et al. CLINICAL CANCER RESEARCH
- Autophagy regulation by p53
- (2010) Maria Chiara Maiuri et al. CURRENT OPINION IN CELL BIOLOGY
- Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1α from human mesenchymal stem cells
- (2010) Eun Su Jeon et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Up-regulation of stromal versican expression in advanced stage serous ovarian cancer
- (2010) Sue Ghosh et al. GYNECOLOGIC ONCOLOGY
- Stromal Compartment as a Survival Prognostic Factor in Advanced Ovarian Carcinoma
- (2010) Alexandre Labiche et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- Regulation of Mammalian Autophagy in Physiology and Pathophysiology
- (2010) Brinda Ravikumar et al. PHYSIOLOGICAL REVIEWS
- Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy
- (2010) C. H. Eng et al. Science Signaling
- Inhibition of PI3k Class III–Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells
- (2010) Roberta Castino et al. TOXICOLOGICAL SCIENCES
- III. Angiogenesis: Complexity of Tumor Vasculature and Microenvironment
- (2009) Mitsuko Furuya et al. CURRENT PHARMACEUTICAL DESIGN
- TGF-β-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM
- (2009) He Chen et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Ovarian cancer cells stimulate uPA gene expression in fibroblastic stromal cells via multiple paracrine and autocrine mechanisms
- (2009) Vera Noskova et al. GYNECOLOGIC ONCOLOGY
- The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans
- (2009) Kellie A. Charles et al. JOURNAL OF CLINICAL INVESTIGATION
- Origin and function of tumor stroma fibroblasts
- (2009) Georgia Xouri et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer
- (2008) Ninke Leffers et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Control of autophagy by oncogenes and tumor suppressor genes
- (2008) M C Maiuri et al. CELL DEATH AND DIFFERENTIATION
- No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
- (2008) Wen Qiu et al. NATURE GENETICS
- Epithelial–stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer
- (2007) James Greenaway et al. GYNECOLOGIC ONCOLOGY
- Cancer-Derived Lysophosphatidic Acid Stimulates Differentiation of Human Mesenchymal Stem Cells to Myofibroblast-Like Cells
- (2007) Eun Su Jeon et al. STEM CELLS
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