Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest

(2012) Ju-Hwa Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

(2012) K Ketola et al.   BRITISH JOURNAL OF CANCER

Nigericin-induced Impairment of Autophagic Flux in Neuronal Cells Is Inhibited by Overexpression of Bak

(2012) Junghyun Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Salinomycin on Cancer Stem Cell in Human Lung Adenocarcinoma A549 Cells

(2012) Yi Wang   Medicinal Chemistry

Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

(2012) C Gong et al.   ONCOGENE

Basal Autophagy Decreased During the Differentiation of Human Adult Mesenchymal Stem Cells

(2012) Lisa Oliver et al.   STEM CELLS AND DEVELOPMENT

Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle

(2011) Saeid Ghavami et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization

(2011) Kwang-Youn Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin can effectively kill ALDHhigh stem-like cells on gastric cancer

(2011) Qiao Ming Zhi et al.   BIOMEDICINE & PHARMACOTHERAPY

Salinomycin inhibits osteosarcoma by targeting its tumor stem cells

(2011) Qing-Lian Tang et al.   CANCER LETTERS

Autophagy positively regulates the CD44+CD24-/lowbreast cancer stem-like phenotype

(2011) Sílvia Cufí et al.   CELL CYCLE

Autophagy is required for self-renewal and differentiation of adult human stem cells

(2011) Souzan Salemi et al.   CELL RESEARCH

Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest

(2011) Won Ki Kim et al.   INVESTIGATIONAL NEW DRUGS

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salinomycin induces calpain and cytochrome c-mediated neuronal cell death

(2011) W Boehmerle et al.   Cell Death & Disease

Evidence for the interplay between JNK and p53-DRAM signaling pathways in the regulation of autophagy

(2010) Séverine Lorin et al.   Autophagy

Autophagic degradation of active caspase-8

(2010) Wen Hou et al.   Autophagy

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells

(2010) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

(2010) Roberta Riccioni et al.   BLOOD CELLS MOLECULES AND DISEASES

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

(2010) Ju-Hwa Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Overview of macroautophagy regulation in mammalian cells

(2010) Maryam Mehrpour et al.   CELL RESEARCH

Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

(2010) Anne Hamacher-Brady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bcl-2 Homology Domain 3 Mimetic Gossypol Induces Both Beclin 1-dependent and Beclin 1-independent Cytoprotective Autophagy in Cancer Cells

(2010) Ping Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells

(2009) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

(2009) E. Charafe-Jauffret et al.   CLINICAL CANCER RESEARCH

Cancer Stem Cells: A New Paradigm for Understanding Tumor Growth and Progression and Drug Resistance

(2009) Rosaria Gangemi et al.   CURRENT MEDICINAL CHEMISTRY

The role of lysosomal rupture in neuronal death

(2009) Tetsumori Yamashima et al.   PROGRESS IN NEUROBIOLOGY

Cathepsin D: A cellular roadmap

(2008) Nousheen Zaidi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One