The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy

Development of a novel, fibrin-specific PET tracer

(2017) Tiemen R. van Mourik et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

‘Philosophy Lost’ : Inquiring into the effects of the corporatized university and its implications for graduate nursing education

(2017) Rusla Anne Springer et al.   Nursing Inquiry

"You can save time if…"—A qualitative study on internal factors slowing down clinical trials in Sub-Saharan Africa

(2017) Nerina Vischer et al.   PLoS One

Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP

(2016) Vikram G. Pillai et al.   BLOOD

Preclinical assessment of a new recombinant ADAMTS-13 drug product (BAX930) for the treatment of thrombotic thrombocytopenic purpura

(2016) A. Kopić et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A minireview on N -acetylcysteine: An old drug with new approaches

(2016) Ines Elbini Dhouib et al.   LIFE SCIENCES

Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura

(2016) Flora Peyvandi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thromboinflammation in Stroke Brain Damage

(2016) Simon F. De Meyer et al.   STROKE

The VWF-GPIb axis in ischaemic stroke: lessons from animal models

(2016) Frederik Denorme et al.   THROMBOSIS AND HAEMOSTASIS

The impact of statin therapy on plasma levels of von Willebrand factor antigen

(2016) Amirhossein Sahebkar et al.   THROMBOSIS AND HAEMOSTASIS

P-Selectin Inhibition Therapeutically Promotes Thrombus Resolution and Prevents Vein Wall Fibrosis Better Than Enoxaparin and an Inhibitor to von Willebrand FactorSignificance

(2015) Jose A. Diaz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

How I treat refractory thrombotic thrombocytopenic purpura

(2015) Farzana A. Sayani et al.   BLOOD

High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion

(2015) D. W. Chung et al.   BLOOD

Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication

(2015) Takafumi Nakano et al.   BRAIN RESEARCH

Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium

(2015) Julia Riegger et al.   EUROPEAN HEART JOURNAL

Roll, adhere, spread and contract: Structural mechanics of platelet function

(2015) Simona Sorrentino et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Nanobodies as Probes for Protein Dynamicsin Vitroand in Cells

(2015) Oleg Y. Dmitriev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquired thrombotic thrombocytopenic purpura: new therapeutic options and their optimal use

(2015) S. R. Cataland et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ADAMTS-13 in Critically Ill Patients With Septic Syndromes and Noninfectious Systemic Inflammatory Response Syndrome

(2015) Jesús Aibar et al.   SHOCK

Recombinant ADAMTS 13 Attenuates Brain Injury After Intracerebral Hemorrhage

(2015) Ping Cai et al.   STROKE

Von Willebrand factor in relation to coronary plaque characteristics and cardiovascular outcome

(2015) Michelle A. Sonneveld et al.   THROMBOSIS AND HAEMOSTASIS

VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP

(2015) Michael Schwameis et al.   THROMBOSIS AND HAEMOSTASIS

von Willebrand Factor Directly Interacts With DNA From Neutrophil Extracellular Traps

(2014) S. Grassle et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Active von Willebrand factor predicts 28-day mortality in patients with systemic inflammatory response syndrome

(2014) A. Hyseni et al.   BLOOD

Of von Willebrand factor and platelets

(2014) Marijke Bryckaert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage

(2014) C. Muroi et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Von Willebrand Factor Regulation in Patients with Acute and Chronic Cerebrovascular Disease: A Pilot, Case–Control Study

(2014) Peter Kraft et al.   PLoS One

Thrombotic Microangiopathies and the Linkage between von Willebrand Factor and the Alternative Complement Pathway

(2014) Nancy Turner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Evaluation of von Willebrand Factor and von Willebrand Factor Propeptide in Models of Vascular Endothelial Cell Activation, Perturbation, and/or Injury

(2014) David A. Brott et al.   TOXICOLOGIC PATHOLOGY

Anti-human VWF monoclonal antibody SZ-123 prevents arterial thrombus formation by inhibiting VWF–collagen and VWF–platelet interactions in Rhesus monkeys

(2013) Yi-ming Zhao et al.   BIOCHEMICAL PHARMACOLOGY

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

ADAMTS13 Predicts Renal and Cardiovascular Events in Type 2 Diabetic Patients and Response to Therapy

(2013) E. Rurali et al.   DIABETES

Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation

(2013) Carina Hillgruber et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Reduced prevalence of arterial thrombosis in von Willebrand disease

(2013) Y. V. Sanders et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ADAMTS13 modulates atherosclerotic plaque progression in mice via a VWF-dependent mechanism

(2013) C. Gandhi et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

(2013) Nancy A. Turner et al.   PLoS One

Recombinant ADAMTS13 reduces tissue plasminogen activator-induced hemorrhage after stroke in mice

(2012) Lixiang Wang et al.   ANNALS OF NEUROLOGY

ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion

(2012) Jolanta M. Siller-Matula et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice

(2012) S. F. De Meyer et al.   BLOOD

ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice

(2012) C. Gandhi et al.   BLOOD

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

The Alternative Complement Pathway Propagates Inflammation and Injury in Murine Ischemic Stroke

(2012) Andrew Elvington et al.   JOURNAL OF IMMUNOLOGY

von Willebrand factor: the old, the new and the unknown

(2012) P. J. LENTING et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Complement activation in thrombotic thrombocytopenic purpura

(2012) M. RÉTI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice

(2012) M. M. KHAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Detection of Extracellular Genomic DNA Scaffold in Human Thrombus: Implications for the Use of Deoxyribonuclease Enzymes in Thrombolysis

(2012) Rahmi Oklu et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

The emerging role of neutrophils in thrombosis—the journey of TF through NETs

(2012) Konstantinos Kambas et al.   Frontiers in Immunology

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor

(2011) J. T. B. Crawley et al.   BLOOD

Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons

(2011) X. Ni et al.   CURRENT MEDICINAL CHEMISTRY

Role of C-Reactive Protein in Acute Myocardial Infarction and Stroke: Possible Therapeutic Approaches

(2011) Paolo Calabro et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

C-reactive protein is released in the coronary circulation and causes endothelial dysfunction in patients with acute coronary syndromes

(2011) Lavinia Forte et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

(2011) Junmei Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The von Willebrand Inhibitor ARC1779 Reduces Cerebral Embolization After Carotid Endarterectomy

(2011) Hugh S. Markus et al.   STROKE

von Willebrand factor promotes leukocyte extravasation

(2010) B. Petri et al.   BLOOD

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High von Willebrand Factor Levels Increase the Risk of Stroke

(2010) Renske G. Wieberdink et al.   STROKE

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

Deficiency of von Willebrand factor protects mice from ischemic stroke

(2009) C. Kleinschnitz et al.   BLOOD

The aptamer ARC1779 is a potent and specific inhibitor of von willebrand factor mediatedex vivoplatelet function in acute myocardial infarction

(2009) Alexander O. Spiel et al.   PLATELETS

Anti-von Willebrand factor aptamer ARC1779 for refractory thrombotic thrombocytopenic purpura

(2009) Paul Knöbl et al.   TRANSFUSION

Human neutrophil peptides: a novel potential mediator of inflammatory cardiovascular diseases

(2008) Kieran Quinn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Integrin  v 3 on human endothelial cells binds von Willebrand factor strings under fluid shear stress

(2008) J. Huang et al.   BLOOD

Inflammation-associated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor

(2008) C. L. Bockmeyer et al.   HAEMATOLOGICA

ADAMTS-13 activity in the presence of elevated von Willebrand factor levels as a novel mechanism of residual platelet reactivity in high risk coronary patients on antiplatelet treatment

(2008) Rossella Marcucci et al.   THROMBOSIS RESEARCH