von Willebrand factor: the old, the new and the unknown

von Willebrand disease: Clinical and laboratory lessons learned from the large von Willebrand disease studies

(2012) Paula D. James et al.   AMERICAN JOURNAL OF HEMATOLOGY

Galectins in acute and chronic inflammation

(2012) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of Galectin-1 and Galectin-3 as Novel Partners for Von Willebrand Factor

(2012) Nathalie Saint-Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion

(2012) S. R. Madabhushi et al.   BLOOD

Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study

(2012) M. Campos et al.   BLOOD

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

Macrophage LRP1 contributes to the clearance of von Willebrand factor

(2012) G. Rastegarlari et al.   BLOOD

Von Willebrand factor deficiency and atherosclerosis

(2012) K.P.M. van Galen et al.   BLOOD REVIEWS

CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators

(2012) Liya Pi et al.   FASEB JOURNAL

Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

(2012) J. N. Pegon et al.   HAEMATOLOGICA

Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

(2012) Dorothee van Breevoort et al.   JOURNAL OF PROTEOME RESEARCH

Effect of ADAM28 on Carcinoma Cell Metastasis by Cleavage of von Willebrand Factor

(2012) Satsuki Mochizuki et al.   JNCI-Journal of the National Cancer Institute

Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W

(2012) C. M. PRUSS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Different bleeding risk in type 2A and 2M von Willebrand disease: a 2-year prospective study in 107 patients

(2012) G. CASTAMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Shear stress is required for the endocytic uptake of the factor VIII-von Willebrand factor complex by macrophages

(2012) L. CASTRO-NÚÑEZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice

(2012) M. M. KHAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor

(2011) J. T. B. Crawley et al.   BLOOD

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

(2011) C. M. Pruss et al.   BLOOD

ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice

(2011) C. Gandhi et al.   BLOOD

Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region

(2011) X. Fu et al.   BLOOD

A pH-regulated dimeric bouquet in the structure of von Willebrand factor

(2011) Yan-Feng Zhou et al.   EMBO JOURNAL

von Willebrand disease

(2011) Paula D James et al.   GENETICS IN MEDICINE

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

(2011) R. SCHNEPPENHEIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biology and physics of von Willebrand factor concatamers

(2011) T. A. SPRINGER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review

(2011) M. C. VAN SCHIE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cleavage of von Willebrand Factor by Granzyme M Destroys Its Factor VIII Binding Capacity

(2011) Martine J. Hollestelle et al.   PLoS One

von Willebrand Factor

(2011) Simon F. De Meyer et al.   STROKE

von Willebrand Factor Permeates Small Vessels in CADASIL and Inhibits Smooth Muscle Gene Expression

(2011) Xiaojie Zhang et al.   Translational Stroke Research

Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions

(2010) M. Golder et al.   BLOOD

Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B

(2010) J. Rayes et al.   BLOOD

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

von Willebrand factor promotes leukocyte extravasation

(2010) B. Petri et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

Risk factors for venous thrombosis - current understanding from an epidemiological point of view

(2010) Willem M. Lijfering et al.   BRITISH JOURNAL OF HAEMATOLOGY

Disulfide bond reduction of von Willebrand factor by ADAMTS-13

(2010) H.-C. YEH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematologic Effects of Continuous Flow Left Ventricular Assist Devices

(2010) Mark S. Slaughter   Journal of Cardiovascular Translational Research

Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site

(2009) T. J. Raife et al.   BLOOD

How I treat von Willebrand disease

(2009) F. Rodeghiero et al.   BLOOD

Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13

(2009) J. Chen et al.   BLOOD

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

Deficiency of von Willebrand factor protects mice from ischemic stroke

(2009) C. Kleinschnitz et al.   BLOOD

von Willebrand factor to the rescue

(2009) S. F. De Meyer et al.   BLOOD

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

(2009) M. Fujioka et al.   BLOOD

Galectins and Gliomas

(2009) Marie Le Mercier et al.   BRAIN PATHOLOGY

Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress

(2009) Stefano Lancellotti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modifier genes for disorders of thrombosis and hemostasis

(2009) R. J. WESTRICK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The glycoprotein Ibα-von Willebrand factor interaction induces platelet apoptosis

(2009) S. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Low von Willebrand factor: sometimes a risk factor and sometimes a disease

(2009) J. E. Sadler   Hematology-American Society of Hematology Education Program

Von-Willebrand Factor Influences Blood Brain Barrier Permeability and Brain Inflammation in Experimental Allergic Encephalomyelitis

(2008) Rajkumar Noubade et al.   AMERICAN JOURNAL OF PATHOLOGY

Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor

(2008) Marguerite S. Buzza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAMTS13: a new link between thrombosis and inflammation

(2008) Anil K. Chauhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions

(2008) Y. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

(2008) W. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA