Of von Willebrand factor and platelets

Loss of α1β1 Soluble Guanylate Cyclase, the Major Nitric Oxide Receptor, Leads to Moyamoya and Achalasia

(2014) Dominique Hervé et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice

(2014) Y. Morioka et al.   BLOOD

GpIb -VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice

(2014) A. Le Behot et al.   BLOOD

Primary haemostasis: newer insights

(2014) M. C. Berndt et al.   HAEMOPHILIA

Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca2+-dependent activation of platelet Rap1b GTPase

(2013) Gianni Francesco Guidetti et al.   BIOCHEMICAL JOURNAL

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis

(2013) B. Estevez et al.   BLOOD

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

(2013) N. Rydz et al.   BLOOD

Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B-associated thrombocytopenia

(2013) C. Casari et al.   BLOOD

Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice

(2013) M. Morowski et al.   BLOOD

Reperfusion of cerebral artery thrombosis by the GPIb-VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs

(2013) S. Momi et al.   BLOOD

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

Thrombocytopathy and type 2B von Willebrand disease

(2013) Jerry Ware   JOURNAL OF CLINICAL INVESTIGATION

von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3

(2013) Caterina Casari et al.   JOURNAL OF CLINICAL INVESTIGATION

The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story

(2013) T. Nightingale et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clearance of von Willebrand factor

(2013) C. Casari et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

(2013) Takehiro Torisu et al.   NATURE MEDICINE

The Role of Rac1 in Glycoprotein Ib-IX–Mediated Signal Transduction and Integrin Activation

(2012) M. Keegan Delaney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heterogeneity of Platelet Functional Alterations in Patients With Filamin A Mutations

(2012) Eliane Berrou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mapping the N-glycome of human von Willebrand factor

(2012) Kevin Canis et al.   BIOCHEMICAL JOURNAL

Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage

(2012) P. M. Jacobi et al.   BLOOD

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

Macrophage LRP1 contributes to the clearance of von Willebrand factor

(2012) G. Rastegarlari et al.   BLOOD

Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

(2012) J. N. Pegon et al.   HAEMATOLOGICA

Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

(2012) Dorothee van Breevoort et al.   JOURNAL OF PROTEOME RESEARCH

Different bleeding risk in type 2A and 2M von Willebrand disease: a 2-year prospective study in 107 patients

(2012) G. CASTAMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Shear stress is required for the endocytic uptake of the factor VIII-von Willebrand factor complex by macrophages

(2012) L. CASTRO-NÚÑEZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Functional architecture of Weibel-Palade bodies

(2011) K. M. Valentijn et al.   BLOOD

VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population

(2011) D. B. Bellissimo et al.   BLOOD

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome

(2011) P. Nurden et al.   BLOOD

Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs

(2011) H. Ulrichts et al.   BLOOD

A pH-regulated dimeric bouquet in the structure of von Willebrand factor

(2011) Yan-Feng Zhou et al.   EMBO JOURNAL

Advances in our understanding of the molecular basis of disorders of platelet function

(2011) A. NURDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

von Willebrand Factor

(2011) Simon F. De Meyer et al.   STROKE

Platelet-type von Willebrand disease update: the disease, the molecule and the animal model

(2011) Maha Othman et al.   Expert Review of Hematology

Binding of von Willebrand Factor to Collagen and Glycoprotein Ibα, But Not to Glycoprotein IIb/IIIa, Contributes to Ischemic Stroke in Mice—Brief Report

(2010) Simon F. De Meyer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Abnormal VWF modifies megakaryocytopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B

(2010) P. Nurden et al.   BLOOD

High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIb -filamin interaction

(2010) S. L. Cranmer et al.   BLOOD

Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B

(2010) J. Rayes et al.   BLOOD

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells

(2010) K. M. Valentijn et al.   BLOOD

The genetic basis of von Willebrand disease

(2010) Anne C. Goodeve   BLOOD REVIEWS

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

(2010) Hervé Falet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Platelet apoptosis by cold-induced glycoprotein Ibα clustering

(2010) D. E. VAN DER WAL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD

(2010) V. H. FLOOD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation

(2009) J. A. Guerrero et al.   BLOOD

Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men

(2009) B. de Laat et al.   BLOOD

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

CalDAG-GEFI is at the nexus of calcium-dependent platelet activation

(2009) L. Stefanini et al.   BLOOD

Selective sorting of alpha-granule proteins

(2009) J. E. ITALIANO JR. et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization

(2009) B. HECHLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The plasma von Willebrand factorO-glycome comprises a surprising variety of structures including ABH antigens and disialosyl motifs

(2009) K. CANIS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The glycoprotein Ibα-von Willebrand factor interaction induces platelet apoptosis

(2009) S. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet Dysfunction and a High Bone Mass Phenotype in a Murine Model of Platelet-Type von Willebrand Disease

(2008) Larry J. Suva et al.   AMERICAN JOURNAL OF PATHOLOGY

The Montreal platelet syndrome kindred has type 2B von Willebrand disease with the VWF V1316M mutation

(2008) S. C. Jackson et al.   BLOOD

A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factor

(2008) L. Gallinaro et al.   BLOOD

Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients

(2008) A. B. Federici et al.   BLOOD

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway

(2008) H. Yin et al.   BLOOD

Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo

(2008) C. J. van Schooten et al.   BLOOD

A functional 14-3-3 -independent association of PI3-kinase with glycoprotein Ib , the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex

(2008) F.-T. Mu et al.   BLOOD

Von Willebrand factor propeptide makes it easy to identify the shorter Von Willebrand factor survival in patients with type 1 and type Vicenza von Willebrand disease

(2008) M. Sztukowska et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Ashwell receptor mitigates the lethal coagulopathy of sepsis

(2008) Prabhjit K Grewal et al.   NATURE MEDICINE

Assembly of Weibel Palade body-like tubules from N-terminal domains of von Willebrand factor

(2008) R.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

(2007) K. Shim et al.   BLOOD

The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation

(2007) H. Yin et al.   BLOOD