Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor
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Title
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor
Authors
Keywords
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Journal
BLOOD
Volume 118, Issue 12, Pages 3212-3221
Publisher
American Society of Hematology
Online
2011-06-30
DOI
10.1182/blood-2011-02-306597
References
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Related references
Note: Only part of the references are listed.- Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13)
- (2011) Y. Xiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amino acid residues Arg659, Arg660, and Tyr661 in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor
- (2010) S.-Y. Jin et al. BLOOD
- Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factor
- (2010) T. A. J. McKinnon et al. BLOOD
- The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function
- (2010) B. M. Luken et al. BLOOD
- The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity
- (2010) R. de Groot et al. BLOOD
- Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura
- (2010) H. B. FEYS et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet-decorated VWF strings in vivo
- (2010) B. DE MAEYER et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- A mechanically stabilized receptor–ligand flex-bond important in the vasculature
- (2010) Jongseong Kim et al. NATURE
- Essential role of the disintegrin-like domain in ADAMTS13 function
- (2009) R. de Groot et al. BLOOD
- An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
- (2009) W. Pos et al. BLOOD
- Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13
- (2009) T. Wu et al. BLOOD
- A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF
- (2009) S. Zanardelli et al. BLOOD
- Circulating ADAMTS-13âvon Willebrand factor complexes: an enzyme on demand
- (2009) J. T. B. CRAWLEY et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Multi-step binding of ADAMTS-13 to von Willebrand factor
- (2009) H. B. FEYS et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor
- (2009) Q. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
- (2009) M. Akiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor
- (2009) X. Zhang et al. SCIENCE
- Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity
- (2008) W. Gao et al. BLOOD
- The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation
- (2008) F. Banno et al. BLOOD
- Basal secretion of von Willebrand factor from human endothelial cells
- (2008) J. P. Giblin et al. BLOOD
- A functional calcium-binding site in the metalloprotease domain of ADAMTS13
- (2008) M. D. Gardner et al. BLOOD
- Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
- (2008) J. E. Sadler BLOOD
- Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack
- (2008) J. T. B. CRAWLEY et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Three-dimensional domain architecture of the ADAM family proteinases
- (2008) Soichi Takeda SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- ADAMTS13 binds to CD36: a potential mechanism for platelet and endothelial localization of ADAMTS13
- (2008) Amanda K. Davis et al. TRANSFUSION
- N-linked glycosylation of VWF modulates its interaction with ADAMTS13
- (2007) T. A. J. McKinnon et al. BLOOD
- Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress
- (2007) K. Shim et al. BLOOD
- Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
- (2007) Lidia Mosyak et al. PROTEIN SCIENCE
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