Cerebrospinal Fluid HIV Escape from Antiretroviral Therapy

Low levels of HIV-1 RNA detected in the cerebrospinal fluid after up to 10 years of suppressive therapy are associated with local immune activation

(2014) Viktor Dahl et al.   AIDS

Short Communication: Focal Encephalitis Related to Viral Escape and Resistance Emergence in Cerebrospinal Fluid in a Patient on Lopinavir/Ritonavir Monotherapy with Plasma HIV-1 RNA Suppression

(2014) Arkaitz Imaz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

ING116070: A Study of the Pharmacokinetics and Antiviral Activity of Dolutegravir in Cerebrospinal Fluid in HIV-1-Infected, Antiretroviral Therapy-Naive Subjects

(2014) S. L. Letendre et al.   CLINICAL INFECTIOUS DISEASES

A Case of Cerebrospinal Fluid Viral Escape on a Dual Antiretroviral Regimen: Worth the Risk?

(2014) Davide Mangioni et al.   CLINICAL INFECTIOUS DISEASES

A Comparative Study of Neurocognitively Impaired Patients Receiving Protease Inhibitor Monotherapy or Triple-Drug Antiretroviral Therapy

(2014) Miriam Estébanez et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Central Nervous System HIV Infection in “Less-Drug Regimen” Antiretroviral Therapy Simplification Strategies

(2014) Nicola Gianotti et al.   SEMINARS IN NEUROLOGY

Evolving clinical phenotypes in HIV-associated neurocognitive disorders

(2014) Ned Sacktor et al.   Current Opinion in HIV and AIDS

Ongoing HIV replication in cerebrospinal fluid under successful monotherapy

(2013) Marieke Bierhoff et al.   ANTIVIRAL THERAPY

Encephalitis with Infiltration by CD8+ Lymphocytes in HIV Patients Receiving Combination Antiretroviral Treatment

(2013) Françoise Gray et al.   BRAIN PATHOLOGY

Cerebrospinal Fluid HIV-1 Compartmentalization in a Patient With AIDS and Acute Varicella-Zoster Virus Meningomyeloradiculitis

(2013) E. Liana Falcone et al.   CLINICAL INFECTIOUS DISEASES

CD8 Encephalitis in HIV-Infected Patients Receiving cART: A Treatable Entity

(2013) François-Xavier Lescure et al.   CLINICAL INFECTIOUS DISEASES

HIV Migration Between Blood and Cerebrospinal Fluid or Semen Over Time

(2013) Antoine Chaillon et al.   JOURNAL OF INFECTIOUS DISEASES

CSF viral escape in a patient with HIV-associated neurocognitive disorder

(2013) Michael N. Khoury et al.   JOURNAL OF NEUROVIROLOGY

Quantification of Entry Phenotypes of Macrophage-Tropic HIV-1 across a Wide Range of CD4 Densities

(2013) S. B. Joseph et al.   JOURNAL OF VIROLOGY

Virological Efficacy in Cerebrospinal Fluid and Neurocognitive Status in Patients with Long-Term Monotherapy Based on Lopinavir/Ritonavir: An Exploratory Study

(2013) José R. Santos et al.   PLoS One

Where does HIV hide? A focus on the central nervous system

(2013) Melissa Churchill et al.   Current Opinion in HIV and AIDS

HIV-1 Pathogenesis: The Virus

(2013) R. Swanstrom et al.   Cold Spring Harbor Perspectives in Medicine

Dual R3R5 tropism characterizes cerebrospinal fluid HIV-1 isolates from individuals with high cerebrospinal fluid viral load

(2012) Ulf Karlsson et al.   AIDS

Central nervous system HIV replication and HIV-related pachymeningitis in a patient on protease inhibitor monotherapy despite an undetectable plasma viral load

(2012) Armelle Pasquet et al.   AIDS

Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load

(2012) Michael J. Peluso et al.   AIDS

Determinants of darunavir cerebrospinal fluid concentrations

(2012) Andrea Calcagno et al.   AIDS

Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration

(2012) D. Croteau et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

(2012) Victor Valcour et al.   JOURNAL OF INFECTIOUS DISEASES

The HIV-1 Env Protein: A Coat of Many Colors

(2012) Kathryn Twigg Arrildt et al.   Current HIV/AIDS Reports

HIV Type 1 Viral Encephalitis After Development of Viral Resistance to Plasma Suppressive Antiretroviral Therapy

(2011) María del Palacio Tamarit et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV encephalitis despite suppressed viraemia: a case of compartmentalized viral escape

(2011) R Bingham et al.   INTERNATIONAL JOURNAL OF STD & AIDS

HIV Coreceptor Tropism in Paired Plasma, Peripheral Blood Mononuclear Cell, and Cerebrospinal Fluid Isolates from Antiretroviral-Naive Subjects

(2011) S. G. Parisi et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Reversible dementia in a patient with central nervous system escape of human immunodeficiency virus

(2011) Isaac I. Bogoch et al.   JOURNAL OF INFECTION

Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral Therapy

(2010) Ana Canestri et al.   CLINICAL INFECTIOUS DISEASES

Therapy Failure following Selection of Enfuvirtide‐Resistant HIV‐1 in Cerebrospinal Fluid

(2010) S. F. L. van Lelyveld et al.   CLINICAL INFECTIOUS DISEASES

HIV‐1 Viral Escape in Cerebrospinal Fluid of Subjects on Suppressive Antiretroviral Treatment

(2010) Arvid Edén et al.   JOURNAL OF INFECTIOUS DISEASES

Cerebrospinal fluid human immunodeficiency virus viral load in patients with neurosyphilis

(2010) Sergio Monteiro de Almeida et al.   JOURNAL OF NEUROVIROLOGY

Darunavir Concentrations in Cerebrospinal Fluid and Blood in HIV-1–Infected Individuals

(2009) Aylin Yilmaz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Presence of HIV-1 R5 Viruses in Cerebrospinal Fluid Even in Patients Harboring R5X4/X4 Viruses in Plasma

(2009) Cathia Soulié et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection

(2009) G. Schnell et al.   JOURNAL OF VIROLOGY

Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia

(2009) Gretja Schnell et al.   PLoS Pathogens

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Antiretroviral Therapy and Central Nervous System HIV Type 1 Infection

(2008) Richard W. Price et al.   JOURNAL OF INFECTIOUS DISEASES

Acute meningoencephalitis due to human immunodeficiency virus type 1 infection in 13 patients: clinical description and follow-up

(2008) S Villar del Saz et al.   JOURNAL OF NEUROVIROLOGY