IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury

CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and l-type Ca2+ channels upstream of p38 MAPK

(2016) Ana B. Sanchez et al.   Journal of Neuroinflammation

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

Antiretrovirals, Methamphetamine, and HIV-1 Envelope Protein gp120 Compromise Neuronal Energy Homeostasis in Association with Various Degrees of Synaptic and Neuritic Damage

(2015) Ana B. Sanchez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combination of methamphetamine and HIV-1 gp120 causes distinct long-term alterations of behavior, gene expression, and injury in the central nervous system

(2015) Melanie M. Hoefer et al.   EXPERIMENTAL NEUROLOGY

Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration

(2015) Jeffrey J Lochhead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HIV-1 and interferons: who's interfering with whom?

(2015) Tomas Doyle et al.   NATURE REVIEWS MICROBIOLOGY

CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120

(2014) Ricky Maung et al.   JOURNAL OF IMMUNOLOGY

An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages

(2014) Faruk Sheikh et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Double-Stranded RNA of Intestinal Commensal but Not Pathogenic Bacteria Triggers Production of Protective Interferon-β

(2013) Tadaomi Kawashima et al.   IMMUNITY

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Canonical Type I IFN Signaling in Simian Immunodeficiency Virus-Infected Macrophages Is Disrupted by Astrocyte-Secreted CCL2

(2012) L. A. Zaritsky et al.   JOURNAL OF IMMUNOLOGY

Anti-Viral and Anti-Inflammatory Mechanisms of the Innate Immune Transcription Factor Interferon Regulatory Factor 3: Relevance to Human CNS Diseases

(2012) Leonid Tarassishin et al.   Journal of Neuroimmune Pharmacology

Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA

(2012) Randi K. Berg et al.   PLoS One

The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment

(2012) Benjamin B. Gelman et al.   PLoS One

Prolonged Antitumor NK Cell Reactivity Elicited by CXCL10-Expressing Dendritic Cells Licensed by CD40L+CD4+ Memory T Cells

(2011) K. Shimizu et al.   JOURNAL OF IMMUNOLOGY

Simian Immunodeficiency Virus Infection in the Brain and Lung Leads to Differential Type I IFN Signaling during Acute Infection

(2011) Luna Alammar et al.   JOURNAL OF IMMUNOLOGY

Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

(2011) Leonid Tarassishin et al.   Journal of Neuroinflammation

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

RIG-I Mediates Innate Immune Response in Mouse Neurons Following Japanese Encephalitis Virus Infection

(2011) Arshed Nazmi et al.   PLoS One

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders

(2010) Yeon-Joo Kang et al.   ANNALS OF NEUROLOGY

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

(2010) R. Khorooshi et al.   JOURNAL OF IMMUNOLOGY

Activation of p38 MAPK Is Required in Monocytic and Neuronal Cells for HIV Glycoprotein 120-Induced Neurotoxicity

(2010) K. E. Medders et al.   JOURNAL OF IMMUNOLOGY

Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-  Signaling To Enhance HIV-1 Replication in Macrophages

(2010) L. N. Akhtar et al.   JOURNAL OF IMMUNOLOGY

HIV-Associated Neurocognitive Disorder: Pathogenesis and Therapeutic Opportunities

(2010) Kathryn A. Lindl et al.   Journal of Neuroimmune Pharmacology

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Neuroprotective Activities of CEP-1347 in Models of NeuroAIDS

(2009) D. Eggert et al.   JOURNAL OF IMMUNOLOGY

Interferon-  Causes Neuronal Dysfunction in Encephalitis

(2009) A. R. Sas et al.   JOURNAL OF NEUROSCIENCE

Lymphotoxin-Mediated Crosstalk between B Cells and Splenic Stroma Promotes the Initial Type I Interferon Response to Cytomegalovirus

(2008) Kirsten Schneider et al.   Cell Host & Microbe

Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in aicardi-Goutières syndrome

(2008) Jane T. Van Heteren et al.   GLIA

Delivery of interferon-β to the monkey nervous system following intranasal administration

(2008) R.G. Thorne et al.   NEUROSCIENCE