A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease

(2015) Habeeb Salameh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

(2015) Paola Dongiovanni et al.   HEPATOLOGY

Genetic variants in or nearADH1BandADH1Caffect susceptibility to alcohol dependence in a British and Irish population

(2014) Michael Way et al.   ADDICTION BIOLOGY

Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis

(2014) A.-J. Chamorro et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Pnpla3I148Mknockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

(2014) Eriks Smagris et al.   HEPATOLOGY

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

(2014) Carlo Pirazzi et al.   HUMAN MOLECULAR GENETICS

A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease

(2014) Hans Dieter Nischalke et al.   JOURNAL OF HEPATOLOGY

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

fcGENE: A Versatile Tool for Processing and Transforming SNP Datasets

(2014) Nab Raj Roshyara et al.   PLoS One

Integrating GWASs and Human Protein Interaction Networks Identifies a Gene Subnetwork Underlying Alcohol Dependence

(2013) Shizhong Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Immediate Listing for Liver Transplantation Versus Standard Care for Child–Pugh Stage B Alcoholic Cirrhosis

(2013) Claire Vanlemmens   ANNALS OF INTERNAL MEDICINE

Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease

(2013) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

Global burden of alcoholic liver diseases

(2013) Jürgen Rehm et al.   JOURNAL OF HEPATOLOGY

Genetics and alcoholism

(2013) Howard J. Edenberg et al.   Nature Reviews Gastroenterology & Hepatology

Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection

(2012) Etienne Patin et al.   GASTROENTEROLOGY

The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

(2011) J. M. Moreno-Navarrete et al.   DIABETES

Artifact due to differential error when cases and controls are imputed from different platforms

(2011) Jennifer A. Sinnott et al.   HUMAN GENETICS

Unknown

(2011) Eleonora Patsenker et al.   MOLECULAR MEDICINE

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

(2011) George F Mells et al.   NATURE GENETICS

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

(2010) Felix Stickel et al.   HEPATOLOGY

Endocannabinoids in liver disease

(2010) Joseph Tam et al.   HEPATOLOGY

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

(2010) Espen Melum et al.   NATURE GENETICS

A genome-wide association study of alcohol dependence

(2010) L. J. Bierut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous Genotype Calling and Haplotype Phasing Improves Genotype Accuracy and Reduces False-Positive Associations for Genome-wide Association Studies

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Liver Transplantation for Alcoholic Liver Disease in Europe: A Study from the ELTR (European Liver Transplant Registry)

(2009) P. Burra et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Genome-wide Association Study of Alcohol Dependence

(2009) Jens Treutlein et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Variant in PNPLA3 is associated with alcoholic liver disease

(2009) Chao Tian et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests

(2008) E. NGUYEN-KHAC et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils

(2008) Miguel A. Gijón et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS