MicroRNA-15b Suppresses Th17 Differentiation and Is Associated with Pathogenesis of Multiple Sclerosis by TargetingO-GlcNAc Transferase

MiR-30a inhibits Th17 differentiation and demyelination of EAE mice by targeting the IL-21R

(2016) Xuebin Qu et al.   BRAIN BEHAVIOR AND IMMUNITY

Programmed Death Ligand 1 Plays a Neuroprotective Role in Experimental Autoimmune Neuritis by Controlling Peripheral Nervous System Inflammation of Rats

(2016) Yanan Ding et al.   JOURNAL OF IMMUNOLOGY

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

(2016) Mahima Swamy et al.   NATURE IMMUNOLOGY

Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions

(2015) Dhavalkumar D. Patel et al.   IMMUNITY

OGT-mediated O-GlcNAcylation promotes NF-κB activation and inflammation in acute pancreatitis

(2015) Dongmei Zhang et al.   INFLAMMATION RESEARCH

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

O-linked N-acetylglucosamine glycosylation of p65 aggravated the inflammation in both fibroblast-like synoviocytes stimulated by tumor necrosis factor-α and mice with collagen induced arthritis

(2015) Han Byeol Kim et al.   ARTHRITIS RESEARCH & THERAPY

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development

(2014) X. Lv et al.   EMBO REPORTS

The role of microRNA-15b in the impaired angiogenesis in diabetic wounds

(2014) Junwang Xu et al.   WOUND REPAIR AND REGENERATION

The role of miRNA in inflammation and autoimmunity

(2013) Ram Pyare Singh et al.   AUTOIMMUNITY REVIEWS

Implications of the O-GlcNAc modification in the regulation of nuclear apoptosis in T cells

(2013) Bruno Johnson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS)

(2013) Margareta Jernås et al.   BMC IMMUNOLOGY

miR-15b Suppression of Bcl-2 Contributes to Cerebral Ischemic Injury and is Reversed by Sevoflurane Preconditioning

(2013) Hong Shi et al.   CNS & Neurological Disorders-Drug Targets

Downregulation of microRNA-15b by hepatitis B virus X enhances hepatocellular carcinoma proliferationviafucosyltransferase 2-induced Globo H expression

(2013) Chen-Shiou Wu et al.   INTERNATIONAL JOURNAL OF CANCER

Overexpression of X-Linked genes in T cells from women with lupus

(2013) Anura Hewagama et al.   JOURNAL OF AUTOIMMUNITY

Dynamically expressed microRNA-15b modulates the activities of CD8+ T lymphocytes in mice with Lewis lung carcinoma

(2013) Guocheng Zhong et al.   Journal of Translational Medicine

Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction

(2013) Sashwati Roy et al.   PLoS One

Activation of the Transcriptional Function of the NF- B Protein c-Rel by O-GlcNAc Glycosylation

(2013) P. Ramakrishnan et al.   Science Signaling

CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis

(2012) Huili Hu et al.   CANCER CELL

MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3

(2012) Xuguang Zheng et al.   CANCER LETTERS

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

(2012) Shu Zhu et al.   NATURE MEDICINE

linking metabolism to epigenetics through O-GlcNAcylation

(2012) John A. Hanover et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

microRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination

(2012) M. P. Mycko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis

(2011) Qingguo Ruan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The NF- B Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis

(2011) G. Chen et al.   JOURNAL OF IMMUNOLOGY

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

(2011) Michael B. Lazarus et al.   NATURE

MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1

(2011) L Sun et al.   ONCOGENE

Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis

(2011) F. Jadidi-Niaragh et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Systematic review of genome-wide expression studies in multiple sclerosis

(2011) A. K. Kemppinen et al.   BMJ Open

MicroRNAs Add a New Dimension to Cardiovascular Disease

(2010) Eric M. Small et al.   CIRCULATION

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

Central nervous system (CNS)–resident natural killer cells suppress Th17 responses and CNS autoimmune pathology

(2010) Junwei Hao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

MicroRNAs miR-17 and miR-20a Inhibit T Cell Activation Genes and Are Under-Expressed in MS Whole Blood

(2010) Mathew B. Cox et al.   PLoS One

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

(2009) Yan Wang et al.   CELL

O-GlcNAc modification of proteins affects volume regulation in Jurkat cells

(2009) Tamás Nagy et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

MicroRNAs: Potential biomarkers for cancer diagnosis, prognosis and targets for therapy

(2009) William C.S. Cho   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MicroRNA in autoimmunity and autoimmune diseases

(2009) Kaleb M. Pauley et al.   JOURNAL OF AUTOIMMUNITY

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis

(2009) Changsheng Du et al.   NATURE IMMUNOLOGY

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Alexander Golks et al.   EMBO REPORTS

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

p38/NF‐kB‐dependent expression of COX‐2 during differentiation and inflammatory response of chondrocytes

(2008) Valentina Ulivi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NF B activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

(2008) W. H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA