4.7 Article

Diagnostic Criteria for Multiple Sclerosis: 2010 Revisions to the McDonald Criteria

Journal

ANNALS OF NEUROLOGY
Volume 69, Issue 2, Pages 292-302

Publisher

WILEY
DOI: 10.1002/ana.22366

Keywords

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Funding

  1. US National Multiple Sclerosis Society (NMSS)
  2. European Committee for Treatment and Research in Multiple Sclerosis
  3. Multiple Sclerosis International Federation
  4. MS Ireland
  5. Biogen Idec
  6. Bayer Schering
  7. Teva
  8. Merck-Serono
  9. Novartis
  10. Glaxo SK
  11. UCB
  12. Demos Medical Publishers (New York, NY)
  13. Multiple Sclerosis Society of Canada
  14. Canadian Institutes of Health Research
  15. Biogen Elan
  16. Merck Serono
  17. Sanofi-Aventis
  18. Department of Defense
  19. NIH
  20. US NMSS
  21. Waterfront Media
  22. ECTRIMS
  23. MSIF
  24. Bayer-Schering
  25. Biogen-Dompe AG
  26. Genmab A/S
  27. Teva Pharmaceutical Industries Ltd
  28. Fondazione Italiana Sclerosi Multipla
  29. Fondazione Mariani
  30. Bayer Schering Pharma
  31. Genmab
  32. Asahi Kasei Kuraray Medical Co Ltd
  33. Chemo-Sero-Therapeutic Research Institute
  34. Mitsubishi Tanabe Pharma
  35. Teijin Pharma
  36. Theva Pharmaceutical
  37. Eisai Inc
  38. Kowa Pharmaceutical
  39. Ministry of Education, Science, and Technology of Japan
  40. Ministry of Health, Labor, and Welfare of Japan
  41. Astellas Pharma
  42. Bayer Healthcare
  43. Health Research Board Ireland
  44. National Research Foundation Switzerland
  45. Rubatto Foundation
  46. Swiss MS society
  47. European Union
  48. Roche Foundation
  49. Novartis Foundation
  50. NMSS
  51. Acorda
  52. Genzyme
  53. EMD Serono
  54. EMD Merck Serono
  55. Genentech
  56. Almirall
  57. Bayer Health Care
  58. Serono Symposia International Foundation
  59. Swedish Bank SEB
  60. National Institute for Health Research
  61. Serono Symposia
  62. MS International Federation
  63. Clayton Foundation for Research

Ask authors/readers for more resources

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use. ANN NEUROL 2011;69:292-302

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