First field evidence of the evolution from a non-virulent HPR0 to a virulent HPR-deleted infectious salmon anaemia virus

Localised Infection of Atlantic Salmon Epithelial Cells by HPR0 Infectious Salmon Anaemia Virus

(2016) Maria Aamelfot et al.   PLoS One

A Unique Multibasic Proteolytic Cleavage Site and Three Mutations in the HA2 Domain Confer High Virulence of H7N1 Avian Influenza Virus in Chickens

(2015) El-Sayed M. Abdelwhab et al.   JOURNAL OF VIROLOGY

Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus

(2015) Andrew S. Taft et al.   Nature Communications

Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease

(2015) Mickael Fourrier et al.   PLoS One

Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

(2014) Martin Linster et al.   CELL

Immersion challenge with low and highly virulent infectious salmon anaemia virus reveals different pathogenesis in Atlantic salmon,Salmo salarL.

(2014) A McBeath et al.   JOURNAL OF FISH DISEASES

Deletions in the highly polymorphic region (HPR) of infectious salmon anaemia virus HPR0 haemagglutinin-esterase enhance viral fusion and influence the interaction with the fusion protein

(2014) M. Fourrier et al.   JOURNAL OF GENERAL VIROLOGY

Emergence of a Highly Pathogenic Avian Influenza Virus from a Low-Pathogenic Progenitor

(2014) I. Monne et al.   JOURNAL OF VIROLOGY

Host adaptation and transmission of influenza A viruses in mammals

(2014) Eefje JA Schrauwen et al.   Emerging Microbes & Infections

Ultra-Deep Pyrosequencing of Partial Surface Protein Genes from Infectious Salmon Anaemia Virus (ISAV) Suggest Novel Mechanisms Involved in Transition to Virulence

(2013) Turhan Markussen et al.   PLoS One

Infectious salmon anaemia virus (ISAV) in Chilean Atlantic salmon (Salmo salar) aquaculture: emergence of low pathogenic ISAV-HPR0 and re-emergence of virulent ISAV-HPR∆: HPR3 and HPR14

(2013) Marcos G Godoy et al.   Virology Journal

Genetic changes that accompanied shifts of low pathogenic avian influenza viruses toward higher pathogenicity in poultry

(2013) El-Sayed M Abdelwhab et al.   Virulence

Low virulent infectious salmon anaemia virus (ISAV-HPR0) is prevalent and geographically structured in Norwegian salmon farming

(2012) TM Lyngstad et al.   DISEASES OF AQUATIC ORGANISMS

Slow release cortisol implants result in impaired innate immune responses and higher infection prevalence following experimental challenge with infectious pancreatic necrosis virus in Atlantic salmon (Salmo salar) parr

(2012) K. Gadan et al.   FISH & SHELLFISH IMMUNOLOGY

Expression of the Infectious Salmon Anemia Virus Receptor on Atlantic Salmon Endothelial Cells Correlates with the Cell Tropism of the Virus

(2012) M. Aamelfot et al.   JOURNAL OF VIROLOGY

Viral Quasispecies Evolution

(2012) E. Domingo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Mutations in Polymerase Genes Enhanced the Virulence of 2009 Pandemic H1N1 Influenza Virus in Mice

(2012) Wenfei Zhu et al.   PLoS One

Depletion of CD8 alpha cells from tissues of Atlantic salmon during the early stages of infection with high or low virulent strains of infectious salmon anaemia virus (ISAV)

(2011) Dyveke Lem Hetland et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

In Vivo Fitness Associated with High Virulence in a Vertebrate Virus Is a Complex Trait Regulated by Host Entry, Replication, and Shedding

(2011) A. R. Wargo et al.   JOURNAL OF VIROLOGY

Epidemiological investigation into the re-emergence and control of an outbreak of infectious salmon anaemia in the Shetland Islands, Scotland

(2010) AG Murray et al.   DISEASES OF AQUATIC ORGANISMS

A low-pathogenic variant of infectious salmon anemia virus (ISAV-HPR0) is highly prevalent and causes a non-clinical transient infection in farmed Atlantic salmon (Salmo salar L.) in the Faroe Islands

(2010) D. H. Christiansen et al.   JOURNAL OF GENERAL VIROLOGY

Use of Molecular Epidemiology to Trace Transmission Pathways for Infectious Salmon Anaemia Virus (ISAV) in Norwegian Salmon Farming

(2010) T.M. Lyngstad et al.   Epidemics

Surveillance for infectious salmon anaemia virus HPR0 in marine Atlantic salmon farms across Scotland

(2009) AJA McBeath et al.   DISEASES OF AQUATIC ORGANISMS

Early viral replication and induced or constitutive immunity in rainbow trout families with differential resistance to Infectious hematopoietic necrosis virus (IHNV)

(2009) Maureen K. Purcell et al.   FISH & SHELLFISH IMMUNOLOGY

In situ localisation of major histocompatibility complex class I and class II and CD8 positive cells in infectious salmon anaemia virus (ISAV)-infected Atlantic salmon

(2009) Dyveke Lem Hetland et al.   FISH & SHELLFISH IMMUNOLOGY

Differential virulence mechanisms of infectious hematopoietic necrosis virus in rainbow trout (Oncorhynchus mykiss) include host entry and virus replication kinetics

(2009) M. M. D. Penaranda et al.   JOURNAL OF GENERAL VIROLOGY

Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice

(2009) T. Rolling et al.   JOURNAL OF VIROLOGY

Molecular Determinants of Adaptation of Highly Pathogenic Avian Influenza H7N7 Viruses to Efficient Replication in the Human Host

(2009) E. de Wit et al.   JOURNAL OF VIROLOGY

Infectious salmon anaemia virus (ISAV) isolated from the ISA disease outbreaks in Chile diverged from ISAV isolates from Norway around 1996 and was disseminated around 2005, based on surface glycoprotein gene sequences

(2009) Frederick SB Kibenge et al.   Virology Journal

First detection, isolation and molecular characterization of infectious salmon anaemia virus associated with clinical disease in farmed Atlantic salmon (Salmo salar) in Chile

(2008) Marcos G Godoy et al.   BMC Veterinary Research

Evolutionary mechanisms involved in the virulence of infectious salmon anaemia virus (ISAV), a piscine orthomyxovirus

(2008) Turhan Markussen et al.   VIROLOGY