Host adaptation and transmission of influenza A viruses in mammals

Novel Avian-Origin Influenza A (H7N9) Virus Attaches to Epithelium in Both Upper and Lower Respiratory Tract of Humans

(2013) Debby van Riel et al.   AMERICAN JOURNAL OF PATHOLOGY

Origin and Molecular Characteristics of a Novel 2013 Avian Influenza A(H6N1) Virus Causing Human Infection in Taiwan

(2013) Jian Yuan et al.   CLINICAL INFECTIOUS DISEASES

Considerations regarding appropriate sample size for conducting ferret transmission experiments

(2013) Jessica A Belser et al.   Future Microbiology

The Short Stalk Length of Highly Pathogenic Avian Influenza H5N1 Virus Neuraminidase Limits Transmission of Pandemic H1N1 Virus in Ferrets

(2013) D. Blumenkrantz et al.   JOURNAL OF VIROLOGY

Adaptation of Avian Influenza A Virus Polymerase in Mammals To Overcome the Host Species Barrier

(2013) B. Manz et al.   JOURNAL OF VIROLOGY

N-Linked Glycosylation of the Hemagglutinin Protein Influences Virulence and Antigenicity of the 1918 Pandemic and Seasonal H1N1 Influenza A Viruses

(2013) X. Sun et al.   JOURNAL OF VIROLOGY

The Homologous Tripartite Viral RNA Polymerase of A/Swine/Korea/CT1204/2009(H1N2) Influenza Virus Synergistically Drives Efficient Replication and Promotes Respiratory Droplet Transmission in Ferrets

(2013) P. N. Q. Pascua et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Increased Acid Stability of the Hemagglutinin Protein Enhances H5N1 Influenza Virus Growth in the Upper Respiratory Tract but Is Insufficient for Transmission in Ferrets

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses

(2013) Di Liu et al.   LANCET

Receptor binding by a ferret-transmissible H5 avian influenza virus

(2013) Xiaoli Xiong et al.   NATURE

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Limited airborne transmission of H7N9 influenza A virus between ferrets

(2013) Mathilde Richard et al.   NATURE

The genesis and source of the H7N9 influenza viruses causing human infections in China

(2013) Tommy Tsan-Yuk Lam et al.   NATURE

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reassortment between Avian H5N1 and Human Influenza Viruses Is Mainly Restricted to the Matrix and Neuraminidase Gene Segments

(2013) Eefje J. A. Schrauwen et al.   PLoS One

Glycosylation on Hemagglutinin Affects the Virulence and Pathogenicity of Pandemic H1N1/2009 Influenza A Virus in Mice

(2013) Yan Zhang et al.   PLoS One

Asparagine Substitution at PB2 Residue 701 Enhances the Replication, Pathogenicity, and Transmission of the 2009 Pandemic H1N1 Influenza A Virus

(2013) Bin Zhou et al.   PLoS One

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

An Airborne Transmissible Avian Influenza H5 Hemagglutinin Seen at the Atomic Level

(2013) W. Zhang et al.   SCIENCE

H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

(2013) Y. Zhang et al.   SCIENCE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation

(2013) X. Qi et al.   BMJ-British Medical Journal

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut)

(2013) Xishan Lu et al.   Protein & Cell

Evolutionary Conservation of the PA-X Open Reading Frame in Segment 3 of Influenza A Virus

(2012) M. Shi et al.   JOURNAL OF VIROLOGY

The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets

(2012) E. J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Evolution of Novel Reassortant A/H3N2 Influenza Viruses in North American Swine and Humans, 2009–2011

(2012) Martha I. Nelson et al.   JOURNAL OF VIROLOGY

Analysis by Single-Gene Reassortment Demonstrates that the 1918 Influenza Virus Is Functionally Compatible with a Low-Pathogenicity Avian Influenza Virus in Mice

(2012) L. Qi et al.   JOURNAL OF VIROLOGY

Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets

(2012) M. B. Pearce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses

(2012) P. N. Q. Pascua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

(2012) B. W. Jagger et al.   SCIENCE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Egyptian H5N1 Influenza Viruses—Cause for Concern?

(2012) Gabriele Neumann et al.   PLoS Pathogens

Insertion of a multibasic cleavage site in the haemagglutinin of human influenza H3N2 virus does not increase pathogenicity in ferrets

(2011) E. J. A. Schrauwen et al.   JOURNAL OF GENERAL VIROLOGY

Infection of immunocompromised patients by avian H9N2 influenza A virus

(2011) Vincent C.C. Cheng et al.   JOURNAL OF INFECTION

The Multibasic Cleavage Site of the Hemagglutinin of Highly Pathogenic A/Vietnam/1203/2004 (H5N1) Avian Influenza Virus Acts as a Virulence Factor in a Host-Specific Manner in Mammals

(2011) A. L. Suguitan et al.   JOURNAL OF VIROLOGY

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

(2011) Taronna R. Maines et al.   VIROLOGY

Genetic analysis and antigenic characterization of swine origin influenza viruses isolated from humans in the United States, 1990–2010

(2011) Bo Shu et al.   VIROLOGY

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity

(2011) Li-Mei Chen et al.   VIROLOGY

Induction and evasion of type I interferon responses by influenza viruses

(2011) Adolfo García-Sastre   VIRUS RESEARCH

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

(2011) Gülsah Gabriel et al.   Nature Communications

Predicting ‘airborne’ influenza viruses: (trans-) mission impossible?

(2011) EM Sorrell et al.   Current Opinion in Virology

Acquisition of Human-Type Receptor Binding Specificity by New H5N1 Influenza Virus Sublineages during Their Emergence in Birds in Egypt

(2011) Yohei Watanabe et al.   PLoS Pathogens

Eurasian-Origin Gene Segments Contribute to the Transmissibility, Aerosol Release, and Morphology of the 2009 Pandemic H1N1 Influenza Virus

(2011) Seema S. Lakdawala et al.   PLoS Pathogens

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

(2011) Zsuzsanna T. Varga et al.   PLoS Pathogens

Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam

(2010) Q. M. Le et al.   JOURNAL OF GENERAL VIROLOGY

PB1-F2 Expression by the 2009 Pandemic H1N1 Influenza Virus Has Minimal Impact on Virulence in Animal Models

(2010) R. Hai et al.   JOURNAL OF VIROLOGY

Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Inefficient Control of Host Gene Expression by the 2009 Pandemic H1N1 Influenza A Virus NS1 Protein

(2010) B. G. Hale et al.   JOURNAL OF VIROLOGY

Glycosylation at 158N of the Hemagglutinin Protein and Receptor Binding Specificity Synergistically Affect the Antigenicity and Immunogenicity of a Live Attenuated H5N1 A/Vietnam/1203/2004 Vaccine Virus in Ferrets

(2010) W. Wang et al.   JOURNAL OF VIROLOGY

In Vitro Assessment of Attachment Pattern and Replication Efficiency of H5N1 Influenza A Viruses with Altered Receptor Specificity

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission

(2010) S. Herfst et al.   JOURNAL OF VIROLOGY

Receptor Specificity and Transmission of H2N2 Subtype Viruses Isolated from the Pandemic of 1957

(2010) Claudia Pappas et al.   PLoS One

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

Neuraminidase Stalk Length and Additional Glycosylation of the Hemagglutinin Influence the Virulence of Influenza H5N1 Viruses for Mice

(2009) Y. Matsuoka et al.   JOURNAL OF VIROLOGY

Reassortment between Avian H5N1 and Human H3N2 Influenza Viruses in Ferrets: a Public Health Risk Assessment

(2009) S. Jackson et al.   JOURNAL OF VIROLOGY

Molecular Determinants of Adaptation of Highly Pathogenic Avian Influenza H7N7 Viruses to Efficient Replication in the Human Host

(2009) E. de Wit et al.   JOURNAL OF VIROLOGY

A Genetically Engineered Waterfowl Influenza Virus with a Deletion in the Stalk of the Neuraminidase Has Increased Virulence for Chickens

(2009) S. Munier et al.   JOURNAL OF VIROLOGY

Blocking Interhost Transmission of Influenza Virus by Vaccination in the Guinea Pig Model

(2009) A. C. Lowen et al.   JOURNAL OF VIROLOGY

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus

(2009) Kathy Hancock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dating the emergence of pandemic influenza viruses

(2009) Gavin J. D. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus

(2009) E. M. Sorrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

(2009) R. J. Garten et al.   SCIENCE

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Avian Influenza H6 Viruses Productively Infect and Cause Illness in Mice and Ferrets

(2008) L. Gillim-Ross et al.   JOURNAL OF VIROLOGY

Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China

(2008) Hua Wang et al.   LANCET

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

(2008) Gülsah Gabriel et al.   PLoS Pathogens

A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

(2008) D. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging influenza

(2007) Emmie de Wit et al.   JOURNAL OF CLINICAL VIROLOGY