Article
Fisheries
Margo E. Chase-Topping, Chris Pooley, Hooman K. Moghadam, Borghild Hillestad, Marie Lillehammer, Lene Sveen, Andrea Doeschl-Wilson
Summary: The experiment tested the impact of vaccination and selective breeding on the transmission of Infectious salmon anemia virus in Atlantic salmon, finding that both methods reduced the probability of infection in contact fish. Genetic resistance showed a more significant effect on infection endurance compared to vaccination.
Article
Virology
Debes Hammershaimb Christiansen, Petra Elisabeth Petersen, Maria Marjunardottir Dahl, Nicolina Vest, Maria Aamelfot, Anja Brathen Kristoffersen, Mona Dverdal Jansen, Iveta Matejusova, Michael D. Gallagher, Gisli Jonsson, Eduardo Rodriguez, Johanna Hol Fosse, Knut Falk
Summary: The nonvirulent infectious salmon anaemia virus (ISAV-HPR0) causes prevalent and transient infections in all three production stages of Atlantic salmon in the Faroe Islands. Different HPR0 subgroups dominate in different stages of production, and vertical transmission of HPR0 from broodfish to progeny is uncommon.
Article
Fisheries
Marina K. V. C. Delphino, Nicole O'Brien, Emilie Laurin, Daryl Whelan, Holly Burnley, Keith Larry Hammell, Krishna Kumar Thakur
Summary: This study used Bayesian latent class analysis to estimate the diagnostic sensitivity and specificity of IFAT and qRT-PCR for detecting Infectious Salmon Anaemia virus. The results showed that qRT-PCR had higher sensitivity and was suitable for routine surveillance. IFAT also had high specificity and was suitable for monitoring ISA.
Article
Immunology
Wenlong Cai, Surendra Kumar, Umasuthan Navaneethaiyer, Albert Caballero-Solares, Laura A. Carvalho, Shona K. Whyte, Sara L. Purcell, Nellie Gagne, Tiago S. Hori, Melissa Allen, Richard G. Taylor, Rachel Balder, Christopher C. Parrish, Matthew L. Rise, Mark D. Fast
Summary: This study investigated the impact of four experimental functional feeds on Atlantic salmon during a single infection with sea lice and a co-infection with sea lice and infectious salmon anemia virus (ISAv). Transcriptomic analysis revealed different gene expression responses in the skin tissues of fish with different experimental diets. The co-infection group showed lower survival rates and up-regulated genes associated with glycolysis and immune response pathways. Understanding the effects of experimental functional feeds on the host response and co-infection trajectory is crucial for developing effective intervention strategies in open cage culture.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biophysics
Maria Elena Tarnok, Fanny Guzman, Luis F. Aguilar
Summary: This study investigated the influence of cholesterol content on membrane fusion facilitated by ISAV fusion peptides. Results showed that cholesterol affected membrane fusion, but the peptides did not require cholesterol in their membranes for fusion in the smallest lipid vesicles (0.2 μm LUV).
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Multidisciplinary Sciences
Simon Chioma Weli, Haitham Tartor, Bjorn Spilsberg, Ole Bendik Dale, Atle Lillehaug
Summary: The study evaluated different membrane filters and buffers for concentration and recovery of ISAV in seawater, finding that the negatively charged MF hydrophilic membrane filter with NucliSENS(R) lysis buffer had the highest ISAV recovery percentages. The ISAV concentration method was more efficient in natural seawater.
Article
Fisheries
D. Ditlecadet, C. Gautreau, L. Boston, R. Liston, E. Johnsen, N. Gagne
Summary: ISAV is the causative agent of infectious salmon anaemia (ISA) which has caused significant economic losses to the Atlantic salmon industry. ISAV variants are identified as pathogenic or non-pathogenic based on the presence or absence of a deletion in the highly polymorphic region (HPR) of segment 6 (S6).
JOURNAL OF FISH DISEASES
(2022)
Article
Fisheries
Joao F. Romero, Ian A. Gardner, Larry Hammell, David Groman, Daryl Whelan, Nicole O'Brien, Leighanne J. Hawkins, Holly Burnley, Krishna Thakur
Summary: This study describes the epidemiology and genetic variants of an ISAV outbreak in southern Newfoundland, Canada in 2020 and 2021. Multiple ISAV variants were identified, including concurrent detection of different variants in one fish. Understanding the disease dynamics and changes is crucial for disease management plans.
JOURNAL OF FISH DISEASES
(2022)
Article
Virology
Daniel G. Hernandez, William Brown, Kerry A. Naish, Gael Kurath
Summary: This study assessed IHNV susceptibility in Chinook salmon populations in the Columbia River Basin, finding little intra-species variation in susceptibility to UC or MD IHNV infection or disease, with a few exceptions in the lower CRB spring-run population. This suggests that factors other than host susceptibility may influence the ecology of IHNV in the CRB.
Article
Agriculture, Dairy & Animal Science
Christin M. Bendorf, Susan C. Yun, Gael Kurath, Ronald P. Hedrick
Summary: This study investigated the susceptibility of California Chinook salmon and steelhead trout to the fish virus infectious hematopoietic necrosis virus (IHNV). The results showed that Chinook salmon had high mortality rates when exposed to IHNV, while steelhead trout had very low mortality rates despite identical virus exposures. Factors such as virus dose, temperature, age, and size of fish were found to affect the mortality rates of Chinook salmon. These findings provide insights into the disease epidemics in California hatchery Chinook salmon.
Review
Fisheries
M. D. Jansen, B. Bang Jensen, M. F. McLoughlin, H. D. Rodger, T. Taksdal, H. Sindre, D. A. Graham, A. Lillehaug
JOURNAL OF FISH DISEASES
(2017)
Article
Multidisciplinary Sciences
Michael D. Gallagher, Iveta Matejusova, Lien Nguyen, Neil M. Ruane, Knut Falk, Daniel J. Macqueen
SCIENTIFIC REPORTS
(2018)
Article
Veterinary Sciences
Mona Dverdal Jansen, Mario Guarracino, Marianne Carson, Ingebjorg Modahl, Torunn Taksdal, Hilde Sindre, Edgar Brun, Saraya Tavornpanich
FRONTIERS IN VETERINARY SCIENCE
(2019)
Article
Fisheries
Lena Hammerlund Teige, Ida Aksnes, Magnus Vikan Rosaeg, Ingvill Jensen, Jorunn Jorgensen, Hilde Sindre, Catherine Collins, Bertrand Collet, Espen Rimstad, Maria K. Dahle, Preben Boysen
FISH & SHELLFISH IMMUNOLOGY
(2020)
Article
Immunology
Nardos Tesfaye Woldemariam, Oleg Agafonov, Hilde Sindre, Bjorn Hoyheim, Ross D. Houston, Diego Robledo, James E. Bron, Rune Andreassen
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Fisheries
Ragnar Thorarinsson, Jeffrey C. Wolf, Makoto Inami, Lisa Phillips, Ginny Jones, Alicia M. Macdonald, Jose F. Rodriguez, Hilde Sindre, Eystein Skjerve, Espen Rimstad, Oystein Evensen
Summary: The DNA vaccine group showed significantly higher SAV3 neutralizing antibody titers after the immunization period, lower SAV3 viremia levels at 19 days post-challenge, reduced transmission of SAV3 to naive fish, higher weight gain, and reduced prevalence/severity of SAV-induced morphological changes in target organs. Additionally, the DNA vaccine group had significantly higher post-challenge survival compared to the Saline group.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Marta Alarcon, Torfinn Moldal, Mona Dverdal Jansen, Maria Aamelfot, Hilde Sindre, Trude M. Lyngstad, Knut Falk
JOURNAL OF FISH DISEASES
(2021)
Article
Virology
Monika J. Hjortaas, Elena Fringuelli, Aderito L. Monjane, Aase B. Mikalsen, Christine M. Jonassen, Paul Savage, Hilde Sindre
Summary: This study conducted full-length genome sequencing of marine salmonid alphavirus genotype 2 (SAV2) samples from Norway and Scotland between 2006 and 2012. The results showed that Norwegian SAV2 strains share a recent common ancestor with Scottish SAV2 strains, but Scottish strains exhibit higher genomic diversity compared to those from Norway. This supports the hypothesis of a single introduction of SAV2 to Norway followed by horizontal spread along the coast.
Article
Cell Biology
Hilde Sindre, Mona C. Gjessing, Johanna Hol Fosse, Lene C. Hermansen, Inger Bockerman, Marit M. Amundsen, Maria K. Dahle, Anita Solhaug
Summary: The establishment of the first Lumpfish Gill cell line (LG-1) provides valuable insights into the biology of lumpfish, with the cells originating from an epithelial or endothelial cell type. LG-1 can serve as an important in vitro research tool for studying gill cell function and host-pathogen interactions in lumpfish.
Article
Fisheries
Camilla Fritsvold, Aase B. Mikalsen, Trygve T. Poppe, Torunn Taksdal, Hilde Sindre
Summary: The study revealed that CMS in young Atlantic salmon exhibited typical clinical symptoms and cardiac lesions, with diseased fish present in the study cage until slaughtering.
JOURNAL OF FISH DISEASES
(2021)
Article
Microbiology
Maria Aamelfot, Johanna Hol Fosse, Hildegunn Viljugrein, Frieda Betty Ploss, Sylvie L. Benestad, Alastair McBeath, Debes Hammershaimb Christiansen, Kyle Garver, Knut Falk
Summary: Infection with ISAV leads to the destruction of the viral vascular surface receptor, resulting in interference with subsequent ISAV attachment. This study provides insights into the kinetics of viral receptor destruction and the potential role of vascular surface modulation in the pathogenesis of infectious salmon anaemia.
Article
Food Science & Technology
Soren Saxmose EFSA Panel Anim Hlth Welf AHAW, Soren Saxmose Nielsen, Julio Alvarez, Paolo Calistri, Elisabetta Canali, Julian Ashley Drewe, Bruno Garin-bastuji, Jose Luis Gonzales Rojas, Christian Gortazar, Mette S. Herskin, Virginie Michel, Miguel Angel Miranda Chueca, Barbara Padalino, Helen Clare Roberts, Hans Spoolder, Karl Stahl, Antonio Velarde, Arvo Viltrop, Christoph Winckler, James Bron, Niels Jorgen Olesen, Hilde Sindre, David Stone, Niccolo Vendramin, Sotiria Eleni Antoniou, Inma Aznar, Alexandra Papanikolaou, Anna Eleonora Karagianni, Dominique Joseph Bicout
Summary: Bacterial kidney disease (BKD) has been assessed for eligibility to be listed for Union intervention according to the criteria of the Animal Health Law. While it meets the eligibility criteria, it does not meet some of the criteria for disease prevention and control categorization.
Article
Food Science & Technology
Soren Saxmose Nielsen, Julio Alvarez, Paolo Calistri, Elisabetta Canali, Julian Ashley Drewe, Bruno Garin-Bastuji, Jose Luis Gonzales Rojas, Christian Gortazar, Mette S. Herskin, Virginie Michel, Miguel Angel Miranda Chueca, Barbara Padalino, Helen Clare Roberts, Hans Spoolder, Karl Stahl, Antonio Velarde, Arvo Viltrop, Christoph Winckler, James Bron, Niels Jorgen Olesen, Hilde Sindre, David Stone, Niccolo Vendramin, Sotiria Eleni Antoniou, Anna Eleonora Karagianni, Alessandro Broglia, Alexandra Papanikolaou, Dominique Joseph Bicout
Summary: The assessment of Spring Viraemia of Carp (SVC) according to the Animal Health Law criteria showed uncertain probabilities for its eligibility to be listed for Union intervention and its categorisation related to disease prevention and control. The assessment also provided criteria for listing animal species related to SVC.
Article
Food Science & Technology
Soren Saxmose Nielsen, Julio EFSA Panel Animal Health Welfare AHAW, Julio Alvarez, Paolo Calistri, Elisabetta Canali, Julian Ashley Drewe, Bruno Garin-Bastuji, Jose Luis Gonzales Rojas, Christian Gortazar, Mette S. Herskin, Virginie Michel, Miguel Angel Miranda Chueca, Barbara Padalino, Helen Clare Roberts, Hans Spoolder, Karl Stahl, Antonio Velarde, Arvo Viltrop, Christoph Winckler, James Bron, Niels Jorgen Olesen, Hilde Sindre, David Stone, Niccolo Vendramin, Sotiria Eleni Antoniou, Anna Eleonora Karagianni, Lisa Kohnle, Alexandra Papanikolaou, Dominique Joseph Bicout
Summary: The assessment based on the Animal Health Law criteria shows that it is uncertain whether infection with G. salaris can be considered eligible for Union intervention. However, the AHAW Panel concluded that the infection does not meet the criteria for categorisation in Section 1 and 3, and the criteria in Sections 2, 4, and 5 are uncertain. The animal species for infection with G. salaris according to Article 8 criteria are provided.
Article
Veterinary Sciences
Trude Marie Lyngstad, Lars Qviller, Hilde Sindre, Edgar Brun, Anja B. Kristoffersen
FRONTIERS IN VETERINARY SCIENCE
(2018)