The nucleus is irreversibly shaped by motion of cell boundaries in cancer and non-cancer cells

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration

(2016) Xuan Cao et al.   BIOPHYSICAL JOURNAL

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

Volume regulation and shape bifurcation in the cell nucleus

(2016) Dong-Hwee Kim et al.   JOURNAL OF CELL SCIENCE

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

(2016) Hawa-Racine Thiam et al.   Nature Communications

Vertical uniformity of cells and nuclei in epithelial monolayers

(2016) Srujana Neelam et al.   Scientific Reports

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

(2016) Samer G. Alam et al.   Scientific Reports

Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

(2015) Yuan Li et al.   BIOPHYSICAL JOURNAL

A mechanical model to investigate the role of the nucleus during confined cell migration

(2015) R. Allena et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Wash Interacts with Lamin and Affects Global Nuclear Organization

(2015) Jeffrey M. Verboon et al.   CURRENT BIOLOGY

Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

(2015) Patricia M. Davidson et al.   Integrative Biology

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell

(2015) Srujana Neelam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites

(2014) Marie Versaevel et al.   Scientific Reports

The regulation of dynamic mechanical coupling between actin cytoskeleton and nucleus by matrix geometry

(2013) Qingsen Li et al.   BIOMATERIALS

Guidance of Cell Migration by Substrate Dimension

(2013) Stephanie S. Chang et al.   BIOPHYSICAL JOURNAL

Nuclear Positioning

(2013) Gregg G. Gundersen et al.   CELL

Mechanical model of blebbing in nuclear lamin meshworks

(2013) Chloe M. Funkhouser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Histone H1 compacts DNA under force and during chromatin assembly

(2012) Botao Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Role of Actin Dependent Nuclear Deformation in Regulating Early Gene Expression

(2012) Soumya Gupta et al.   PLoS One

Spatial coordination between cell and nuclear shape within micropatterned endothelial cells

(2012) Marie Versaevel et al.   Nature Communications

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

(2009) M. Webster et al.   JOURNAL OF CELL SCIENCE

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonlinear Osmotic Properties of the Cell Nucleus

(2008) John D. Finan et al.   ANNALS OF BIOMEDICAL ENGINEERING