Microtubules in 3D cell motility

Engineered Models of Confined Cell Migration

(2016) Colin D. Paul et al.   Annual Review of Biomedical Engineering

Microtubule plus-end tracking proteins in neuronal development

(2016) Dieudonnée van de Willige et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multiple mechanisms of 3D migration: the origins of plasticity

(2016) Ryan J Petrie et al.   CURRENT OPINION IN CELL BIOLOGY

The emerging role of the tubulin code: From the tubulin molecule to neuronal function and disease

(2016) Soumyananda Chakraborti et al.   Cytoskeleton

Podosome dynamics and location in vascular smooth muscle cells require CLASP-dependent microtubule bending

(2016) Xiaodong Zhu et al.   Cytoskeleton

Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration

(2016) Laurel E. Hind et al.   DEVELOPMENTAL CELL

Focal adhesions, stress fibers and mechanical tension

(2016) Keith Burridge et al.   EXPERIMENTAL CELL RESEARCH

The microenvironment controls invadosome plasticity

(2016) Julie Di Martino et al.   JOURNAL OF CELL SCIENCE

The front and rear of collective cell migration

(2016) Roberto Mayor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes

(2016) P. Robison et al.   SCIENCE

Accelerated actin filament polymerization from microtubule plus ends

(2016) J. L. Henty-Ridilla et al.   SCIENCE

In vivo epidermal migration requires focal adhesion targeting of ACF7

(2016) Jiping Yue et al.   Nature Communications

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions

(2016) Benjamin P Bouchet et al.   eLife

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies

(2016) Xun Chen et al.   Journal of Cancer

Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks

(2015) Shawn P. Carey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Podosomes and invadopodia: tools to breach vascular basement membrane

(2015) Giorgio Seano et al.   CELL CYCLE

Control of polarized assembly of actin filaments in cell motility

(2015) Marie-France Carlier et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microtubule Minus-End-Targeting Proteins

(2015) Anna Akhmanova et al.   CURRENT BIOLOGY

Coordinating Neuronal Actin–Microtubule Dynamics

(2015) Charlotte H. Coles et al.   CURRENT BIOLOGY

Endocytic Trafficking of Integrins in Cell Migration

(2015) Nikki R. Paul et al.   CURRENT BIOLOGY

Rho family GTPases: Making it to the third dimension

(2015) Kristin M. Riching et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

(2015) Norio Yamashita et al.   JOURNAL OF BIOMEDICAL OPTICS

Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing

(2015) Rabab A. Charafeddine et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography

(2015) Mikhail Eltsov et al.   NATURE CELL BIOLOGY

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Building the Neuronal Microtubule Cytoskeleton

(2015) Lukas C. Kapitein et al.   NEURON

Post-translational modifications of tubulin: pathways to functional diversity of microtubules

(2015) Yuyu Song et al.   TRENDS IN CELL BIOLOGY

Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3

(2015) Lauriane Velot et al.   Oncotarget

Invasive leader cells: metastatic oncotarget

(2015) Kevin J. Cheung et al.   Oncotarget

Dynamic Microtubules Catalyze Formation of Navigator-TRIO Complexes to Regulate Neurite Extension

(2014) Jeffrey van Haren et al.   CURRENT BIOLOGY

Microtubule acetylation regulates dynamics of KIF1C-powered vesicles and contact of microtubule plus ends with podosomes

(2014) Ridhirama Bhuwania et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

End-binding protein 1 (EB1) up-regulation is an early event in colorectal carcinogenesis

(2014) Yolanda Stypula-Cyrus et al.   FEBS LETTERS

Control of macrophage 3D migration: a therapeutic challenge to limit tissue infiltration

(2014) Isabelle Maridonneau-Parini   IMMUNOLOGICAL REVIEWS

Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration

(2014) Nicholas O. Deakin et al.   JOURNAL OF CELL BIOLOGY

A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

(2014) Emanuela Frittoli et al.   JOURNAL OF CELL BIOLOGY

Podosome-regulating kinesin KIF1C translocates to the cell periphery in a CLASP-dependent manner

(2014) N. Efimova et al.   JOURNAL OF CELL SCIENCE

CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer

(2014) I. R. Macpherson et al.   JOURNAL OF CELL SCIENCE

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

(2014) Samantha J. Stehbens et al.   NATURE CELL BIOLOGY

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

(2014) Eliah R. Shamir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

(2014) C. Rosse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

The multiple faces of leukocyte interstitial migration

(2014) Tim Lämmermann et al.   Seminars in Immunopathology

Rho GTPase isoforms in cell motility: Don't fret, we have FRET

(2014) Sara K Donnelly et al.   Cell Adhesion & Migration

Microtubules in Cell Migration

(2013) Sandrine Etienne-Manneville   Annual Review of Cell and Developmental Biology

ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics

(2013) A. Molina et al.   CANCER RESEARCH

Interstitial leukocyte migration in vivo

(2013) Pui-ying Lam et al.   CURRENT OPINION IN CELL BIOLOGY

Role of adhesion receptor trafficking in 3D cell migration

(2013) Guillaume Jacquemet et al.   CURRENT OPINION IN CELL BIOLOGY

Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion

(2013) R. Moore et al.   DEVELOPMENT

CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor

(2013) Babet van der Vaart et al.   DEVELOPMENTAL CELL

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

At the leading edge of three-dimensional cell migration

(2013) R. J. Petrie et al.   JOURNAL OF CELL SCIENCE

Microtubule Dynamic Instability Controls Podosome Patterning in Osteoclasts through EB1, Cortactin, and Src

(2013) M. Biosse Duplan et al.   MOLECULAR AND CELLULAR BIOLOGY

αTAT1 catalyses microtubule acetylation at clathrin-coated pits

(2013) Guillaume Montagnac et al.   NATURE

Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy

(2013) Yicong Wu et al.   NATURE BIOTECHNOLOGY

Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel

(2013) Jun Oyanagi et al.   PLoS One

Intravital FRET Imaging of Tumor Cell Viability and Mitosis during Chemotherapy

(2013) Aniek Janssen et al.   PLoS One

Mechanism for the catastrophe-promoting activity of the microtubule destabilizer Op18/stathmin

(2013) K. K. Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for microtubules in endothelial cell protrusion in three-dimensional matrices

(2012) Gabriel G. Martins et al.   BIOLOGY OF THE CELL

EB1-Recruited Microtubule +TIP Complexes Coordinate Protrusion Dynamics during 3D Epithelial Remodeling

(2012) Sarah Gierke et al.   CURRENT BIOLOGY

Epithelial-mesenchymal transitions: insights from development

(2012) J. Lim et al.   DEVELOPMENT

PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration through Its Substrate Rabaptin-5

(2012) Claudine Christoforides et al.   DEVELOPMENTAL CELL

The Microtubule-Associated Rho Activating Factor GEF-H1 Interacts with Exocyst Complex to Regulate Vesicle Traffic

(2012) Ritu Pathak et al.   DEVELOPMENTAL CELL

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype

(2012) Martin H. Hager et al.   EMBO Molecular Medicine

ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion

(2012) Antonio Castro-Castro et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Targeting and transport: How microtubules control focal adhesion dynamics

(2012) Samantha Stehbens et al.   JOURNAL OF CELL BIOLOGY

N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

(2012) Xinzi Yu et al.   JOURNAL OF CELL BIOLOGY

Spectraplakins: Master orchestrators of cytoskeletal dynamics

(2012) Kathleen C. Suozzi et al.   JOURNAL OF CELL BIOLOGY

Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex

(2012) Yu Wang et al.   JOURNAL OF CELL BIOLOGY

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion

(2012) Eishu Hirata et al.   JOURNAL OF CELL SCIENCE

The role of microtubules in neutrophil polarity and migration in live zebrafish

(2012) S. K. Yoo et al.   JOURNAL OF CELL SCIENCE

Microtubule-severing enzymes at the cutting edge

(2012) D. J. Sharp et al.   JOURNAL OF CELL SCIENCE

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness

(2012) Jessica N. Heck et al.   MOLECULAR BIOLOGY OF THE CELL

Analysis of axonal growth and cell migration in 3D hydrogel cultures of embryonic mouse CNS tissue

(2012) Vanessa Gil et al.   Nature Protocols

Cytoskeleton in action: lissencephaly, a neuronal migration disorder

(2012) Hyang Mi Moon et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Targeting tumor cell motility to prevent metastasis

(2011) Trenis D. Palmer et al.   ADVANCED DRUG DELIVERY REVIEWS

Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53

(2011) P. Timpson et al.   CANCER RESEARCH

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Endosomal signaling and cell migration

(2011) Natalia Schiefermeier et al.   CURRENT OPINION IN CELL BIOLOGY

VAB-10 spectraplakin acts in cell and nuclear migration in Caenorhabditis elegans

(2011) H.-S. Kim et al.   DEVELOPMENT

Rac1 Drives Melanoblast Organization during Mouse Development by Orchestrating Pseudopod- Driven Motility and Cell-Cycle Progression

(2011) Ang Li et al.   DEVELOPMENTAL CELL

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

p21Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells

(2011) Benjamin Pierre Bouchet et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Stathmin: a protein with many tasks. New biomarker and potential target in cancer

(2011) Barbara Belletti et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis

(2011) Kenneth A. Myers et al.   JOURNAL OF CELL BIOLOGY

Cell-matrix adhesions in 3D

(2011) Jill S. Harunaga et al.   MATRIX BIOLOGY

Glioblastoma motility occurs in the absence of actin polymer

(2011) Andreas Panopoulos et al.   MOLECULAR BIOLOGY OF THE CELL

The proliferation rate paradox in antimitotic chemotherapy

(2011) Timothy J. Mitchison   MOLECULAR BIOLOGY OF THE CELL

Mitosis is not a key target of microtubule agents in patient tumors

(2011) Edina Komlodi-Pasztor et al.   Nature Reviews Clinical Oncology

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules

(2011) N. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microscopy in 3D: a biologist's toolbox

(2011) Robert S. Fischer et al.   TRENDS IN CELL BIOLOGY

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages

(2010) C. Wiesner et al.   BLOOD

Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae

(2010) Sara A. Wickström et al.   DEVELOPMENTAL CELL

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

(2010) Claire Rooney et al.   EMBO REPORTS

HDAC6 is required for invadopodia activity and invasion by breast tumor cells

(2010) Mercedes Rey et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion inDrosophilamacrophages in vivo

(2010) Brian Stramer et al.   JOURNAL OF CELL BIOLOGY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

MAP1B Regulates Axonal Development by Modulating Rho-GTPase Rac1 Activity

(2010) Carolina Montenegro-Venegas et al.   MOLECULAR BIOLOGY OF THE CELL

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes

(2010) Susanne Cornfine et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Cell migration during morphogenesis

(2009) Andy Aman et al.   DEVELOPMENTAL BIOLOGY

Mechanics of microtubules

(2009) Taviare Hawkins et al.   JOURNAL OF BIOMECHANICS

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion

(2009) M. J. Kean et al.   JOURNAL OF CELL SCIENCE

The elastic modulus of Matrigel™ as determined by atomic force microscopy

(2009) Shauheen S. Soofi et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Primary Role for Golgi Positioning in Directed Secretion, Cell Polarity, and Wound Healing

(2009) Smita Yadav et al.   MOLECULAR BIOLOGY OF THE CELL

Guanine Nucleotide Exchange Factor-H1 Regulates Cell Migration via Localized Activation of RhoA at the Leading Edge

(2009) Perihan Nalbant et al.   MOLECULAR BIOLOGY OF THE CELL

A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivo

(2009) Elena Kardash et al.   NATURE CELL BIOLOGY

Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells

(2009) Paul M. Miller et al.   NATURE CELL BIOLOGY

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness

(2008) Truong-An Tran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell biology of embryonic migration

(2008) Satoshi Kurosaka et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

WAVE2- and microtubule-dependent formation of long protrusions and invasion of cancer cells cultured on three-dimensional extracellular matrices

(2008) Keiji Kikuchi et al.   CANCER SCIENCE

ACF7 Regulates Cytoskeletal-Focal Adhesion Dynamics and Migration and Has ATPase Activity

(2008) Xiaoyang Wu et al.   CELL

Caveolin-1 in cell polarization and directional migration

(2008) A GRANDEGARCIA et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

(2008) Francesca Bartolini et al.   JOURNAL OF CELL BIOLOGY

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Stathmin Activity Influences Sarcoma Cell Shape, Motility, and Metastatic Potential

(2008) Barbara Belletti et al.   MOLECULAR BIOLOGY OF THE CELL

EB1 acts as an oncogene via activating β-catenin/TCF pathway to promote cellular growth and inhibit apoptosis

(2008) Mei Liu et al.   MOLECULAR CARCINOGENESIS

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

(2008) Yukiko Nakaya et al.   NATURE CELL BIOLOGY

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

(2008) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration

(2008) Christophe Le Clainche et al.   PHYSIOLOGICAL REVIEWS

The making of a melanocyte: the specification of melanoblasts from the neural crest

(2008) Aaron J. Thomas et al.   Pigment Cell & Melanoma Research

Force-generation and dynamic instability of microtubule bundles

(2008) Liedewij Laan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA