Rho GTPase isoforms in cell motility: Don't fret, we have FRET

A Trio–Rac1–Pak1 signalling axis drives invadopodia disassembly

(2014) Yasmin Moshfegh et al.   NATURE CELL BIOLOGY

A New Genetically Encoded Single-Chain Biosensor for Cdc42 Based on FRET, Useful for Live-Cell Imaging

(2014) Samer Hanna et al.   PLoS One

Podosomes in space

(2014) Christiane Wiesner et al.   Cell Adhesion & Migration

The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues

(2014) Anna-Karin E. Johnsson et al.   Cell Reports

Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

(2013) Caroline Gest et al.   BMC CANCER

Signaling networks of Rho GTPases in cell motility

(2013) Samer Hanna et al.   CELLULAR SIGNALLING

Interstitial leukocyte migration in vivo

(2013) Pui-ying Lam et al.   CURRENT OPINION IN CELL BIOLOGY

Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders

(2013) Anja Troeger et al.   EXPERIMENTAL CELL RESEARCH

GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation

(2013) C. H. Fernandez-Espartero et al.   JOURNAL OF CELL SCIENCE

Spatial regulation of RhoC activity defines protrusion formation in migrating cells

(2013) J. J. Bravo-Cordero et al.   JOURNAL OF CELL SCIENCE

RhoA, RhoB and RhoC have different roles in cancer cell migration

(2013) A.J. RIDLEY   JOURNAL OF MICROSCOPY

Rab11 regulates cell–cell communication during collective cell movements

(2013) Damien Ramel et al.   NATURE CELL BIOLOGY

Functions of cofilin in cell locomotion and invasion

(2013) Jose Javier Bravo-Cordero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell intercalation from top to bottom

(2013) Elise Walck-Shannon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ephrin-B1 Controls the Columnar Distribution of Cortical Pyramidal Neurons by Restricting Their Tangential Migration

(2013) Jordane Dimidschstein et al.   NEURON

Roles of Rho GTPases in leucocyte and leukaemia cell transendothelial migration

(2013) E. Infante et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Regulation of Small GTPases by GEFs, GAPs, and GDIs

(2013) Jacqueline Cherfils et al.   PHYSIOLOGICAL REVIEWS

A RhoC Biosensor Reveals Differences in the Activation Kinetics of RhoA and RhoC in Migrating Cells

(2013) Jon S. Zawistowski et al.   PLoS One

GTP Hydrolysis of TC10 Promotes Neurite Outgrowth through Exocytic Fusion of Rab11- and L1-Containing Vesicles by Releasing Exocyst Component Exo70

(2013) Akane Fujita et al.   PLoS One

RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission

(2013) B. Schwechter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space

(2013) R. D. Fritz et al.   Science Signaling

Cytoskeleton responses in wound repair

(2012) Maria Teresa Abreu-Blanco et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RhoB regulates uPAR signalling

(2012) D. Alfano et al.   JOURNAL OF CELL SCIENCE

In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion

(2012) Eishu Hirata et al.   JOURNAL OF CELL SCIENCE

Activity of PLC  contributes to chemotaxis of fibroblasts towards PDGF

(2012) M. Martins et al.   JOURNAL OF CELL SCIENCE

RhoB regulates cell migration through altered focal adhesion dynamics

(2012) F. M. Vega et al.   Open Biology

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG

(2011) L. Yuan et al.   BLOOD

Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53

(2011) P. Timpson et al.   CANCER RESEARCH

Signaling networks regulating leukocyte podosome dynamics and function

(2011) Athanassios Dovas et al.   CELLULAR SIGNALLING

A Novel Spatiotemporal RhoC Activation Pathway Locally Regulates Cofilin Activity at Invadopodia

(2011) Jose Javier Bravo-Cordero et al.   CURRENT BIOLOGY

Directed cell invasion and migration during metastasis

(2011) Jose Javier Bravo-Cordero et al.   CURRENT OPINION IN CELL BIOLOGY

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

(2011) Francisco M. Vega et al.   JOURNAL OF CELL BIOLOGY

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus

(2011) Roberta Pennucci et al.   PLoS One

Dynamics of the Rho-family small GTPases in actin regulation and motility

(2011) Désirée Spiering et al.   Cell Adhesion & Migration

Critical roles for Rac GTPases in T-cell migration to and within lymph nodes

(2010) M. Faroudi et al.   BLOOD

Rac and Rho GTPases in cancer cell motility control

(2010) Matteo Parri et al.   Cell Communication and Signaling

Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish

(2010) Sa Kan Yoo et al.   DEVELOPMENTAL CELL

Scaffold Proteins IRSp53 and Spinophilin Regulate Localized Rac Activation by T-lymphocyte Invasion and Metastasis Protein 1 (TIAM1)

(2010) Soumitra Rajagopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

(2010) Sarah J. Heasman et al.   JOURNAL OF CELL BIOLOGY

Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo

(2010) Haibo Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival

(2010) Robert B. Henderson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo

(2010) Xiaobo Wang et al.   NATURE CELL BIOLOGY

Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells

(2009) Verena Niggli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Essential role of Rac1 and Rac3 GTPases in neuronal development

(2009) Sara Corbetta et al.   FASEB JOURNAL

Wound repair at a glance

(2009) T. J. Shaw et al.   JOURNAL OF CELL SCIENCE

Human Neutrophils Coordinate Chemotaxis by Differential Activation of Rac1 and Rac2

(2009) H. Zhang et al.   JOURNAL OF IMMUNOLOGY

Cdc42 and Rac Family GTPases Regulate Mode and Speed but Not Direction of Primary Fibroblast Migration during Platelet-Derived Growth Factor-Dependent Chemotaxis

(2009) J. Monypenny et al.   MOLECULAR AND CELLULAR BIOLOGY

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivo

(2009) Elena Kardash et al.   NATURE CELL BIOLOGY

Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA

(2008) H. K. Matthews et al.   DEVELOPMENT

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY