Differences in the secretion and transport of Wnt proteins

Exosomes in developmental signalling

(2016) Ian John McGough et al.   DEVELOPMENT

Role of cytonemes in Wnt transport

(2016) Eliana Stanganello et al.   JOURNAL OF CELL SCIENCE

Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs

(2016) Yasuo Yamazaki et al.   NATURE CELL BIOLOGY

Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin

(2016) Emiko Mihara et al.   eLife

Different populations of Wnt-containing vesicles are individually released from polarized epithelial cells

(2016) Qiuhong Chen et al.   Scientific Reports

Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling

(2015) S. W. Fellgett et al.   JOURNAL OF CELL SCIENCE

Filopodia-based Wnt transport during vertebrate tissue patterning

(2015) Eliana Stanganello et al.   Nature Communications

Migrating cells mediate long-range WNT signaling

(2014) O. Serralbo et al.   DEVELOPMENT

Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm

(2014) Marta Luz et al.   PLoS One

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms

(2013) H. Yamamoto et al.   JOURNAL OF CELL SCIENCE

Structural Studies of Wnts and Identification of an LRP6 Binding Site

(2013) Matthew Ling-Hon Chu et al.   STRUCTURE

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Live imaging of active fluorophore labelled Wnt proteins

(2012) Tatjana Holzer et al.   FEBS LETTERS

Heparan Sulfate 6-O-endosulfatases (Sulfs) Coordinate the Wnt Signaling Pathways to Regulate Myoblast Fusion during Skeletal Muscle Regeneration

(2012) Thanh H. Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Porcupine impairs convergent extension during gastrulation in zebrafish

(2012) Q. Chen et al.   JOURNAL OF CELL SCIENCE

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Drosophila S2 Cells Secrete Wingless on Exosome-Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

(2012) Karen Beckett et al.   TRAFFIC

Wnt Proteins

(2012) K. Willert et al.   Cold Spring Harbor Perspectives in Biology

Role of Sulf1A in Wnt1- and Wnt6-induced growth regulation and myoblast hyper-elongation

(2012) L. Hitchins et al.   FEBS Open Bio

Secreted frizzled-related proteins are required for Wnt/ -catenin signalling activation in the vertebrate optic cup

(2011) P. Esteve et al.   DEVELOPMENT

Secreted Wnt “inhibitors” are not just inhibitors: Regulation of extracellular Wnt by secreted Frizzled-related proteins

(2011) Yusuke Mii et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Sulfated is a negative feedback regulator of wingless in Drosophila

(2011) Jia You et al.   DEVELOPMENTAL DYNAMICS

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

(2011) K. A. Mulligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation

(2010) Adam Kleinschmit et al.   DEVELOPMENTAL BIOLOGY

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

(2010) G. S. Coombs et al.   JOURNAL OF CELL SCIENCE

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

(2009) Y. Mii et al.   DEVELOPMENT

Functional Consequences of the Subdomain Organization of the Sulfs

(2009) Renhong Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Wnt3a is Released on Lipoprotein Particles

(2009) Sylvia Neumann et al.   TRAFFIC

Shaping Morphogen Gradients by Proteoglycans

(2009) D. Yan et al.   Cold Spring Harbor Perspectives in Biology

Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila

(2008) Vladimir L Katanaev et al.   EMBO JOURNAL

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE