Secreted Wnt “inhibitors” are not just inhibitors: Regulation of extracellular Wnt by secreted Frizzled-related proteins

Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein

(2011) M. Harterink et al.   DEVELOPMENT

Dorsal–Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases

(2011) Diego Ploper et al.   DEVELOPMENTAL BIOLOGY

Specificity of Drosophila Cytonemes for Distinct Signaling Pathways

(2011) S. Roy et al.   SCIENCE

Role of Secreted Frizzled-Related Protein 3 in Human Renal Cell Carcinoma

(2010) H. Hirata et al.   CANCER RESEARCH

Lighting up developmental mechanisms: how fluorescence imaging heralded a new era

(2010) M. Mavrakis et al.   DEVELOPMENT

Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response

(2010) Kyle A. Gurley et al.   DEVELOPMENTAL BIOLOGY

Structure and expression of conserved Wnt pathway components in the demosponge Amphimedon queenslandica

(2010) Maja Adamska et al.   EVOLUTION & DEVELOPMENT

Localization, anchoring and translational control ofoskar,gurken,bicoidandnanosmRNA during Drosophila oogenesis

(2010) Jan-Michael Kugler et al.   FLY

Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer

(2010) Kazumori Kawakami et al.   INTERNATIONAL JOURNAL OF CANCER

Oncogenic Functions of Secreted Frizzled-Related Protein 2 in Human Renal Cancer

(2010) S. Yamamura et al.   MOLECULAR CANCER THERAPEUTICS

International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors

(2010) G. Schulte   PHARMACOLOGICAL REVIEWS

Scaling of morphogen gradients by an expansion-repression integral feedback control

(2010) D. Ben-Zvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt11/5a Complex Formation Caused by Tyrosine Sulfation Increases Canonical Signaling Activity

(2009) Sang-Wook Cha et al.   CURRENT BIOLOGY

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

(2009) Y. Mii et al.   DEVELOPMENT

Rise of the source–sink model

(2009) Alexander F. Schier et al.   NATURE

Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules

(2009) Shuizi Rachel Yu et al.   NATURE

FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

(2009) Masayo Harada et al.   NATURE GENETICS

Forming and Interpreting Gradients in the Early Xenopus Embryo

(2009) J. C. Smith   Cold Spring Harbor Perspectives in Biology

Shaping Morphogen Gradients by Proteoglycans

(2009) D. Yan et al.   Cold Spring Harbor Perspectives in Biology

Robust Stability of the Embryonic Axial Pattern Requires a Secreted Scaffold for Chordin Degradation

(2008) Hidehiko Inomata et al.   CELL

Sfrp1 and Sfrp2 are required for normal male sexual development in mice

(2008) Nick Warr et al.   DEVELOPMENTAL BIOLOGY

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling

(2008) Y. Li et al.   GENES & DEVELOPMENT

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/β-catenin and the planar cell polarity pathways during early trunk formation in mouse

(2008) Wataru Satoh et al.   GENESIS

Retinoic acid signaling in development: Tissue-specific functions and evolutionary origins

(2008) Florent Campo-Paysaa et al.   GENESIS

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE

Scaling of the BMP activation gradient in Xenopus embryos

(2008) Danny Ben-Zvi et al.   NATURE

In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate

(2008) R. G. Thorne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA