Role of cytonemes in Wnt transport

Filopodia in cell adhesion, 3D migration and cancer cell invasion

(2015) Guillaume Jacquemet et al.   CURRENT OPINION IN CELL BIOLOGY

Communication between distant epithelial cells by filopodia-like protrusions during embryonic development

(2015) Sagar et al.   DEVELOPMENT

Switching roles: the functional plasticity of adult tissue stem cells

(2015) A. Wabik et al.   EMBO JOURNAL

Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions

(2015) J. C. Snyder et al.   JOURNAL OF CELL SCIENCE

Nanotubes mediate niche–stem-cell signalling in the Drosophila testis

(2015) Mayu Inaba et al.   NATURE

Filopodia-based Wnt transport during vertebrate tissue patterning

(2015) Eliana Stanganello et al.   Nature Communications

Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

(2015) Hai Huang et al.   eLife

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles

(2015) Kerstin Menck et al.   Oncotarget

Migrating cells mediate long-range WNT signaling

(2014) O. Serralbo et al.   DEVELOPMENT

Cytonemes as specialized signaling filopodia

(2014) T. B. Kornberg et al.   DEVELOPMENT

Vertebrate nervous system posteriorization: Grading the function of Wnt signaling

(2014) David Green et al.   DEVELOPMENTAL DYNAMICS

In vivo analysis of formation and endocytosis of the Wnt/ -Catenin signaling complex in zebrafish embryos

(2014) A. I. H. Hagemann et al.   JOURNAL OF CELL SCIENCE

Glial Wingless/Wnt Regulates Glutamate Receptor Clustering and Synaptic Physiology at the Drosophila Neuromuscular Junction

(2014) K. S. Kerr et al.   JOURNAL OF NEUROSCIENCE

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors

(2014) David J Kast et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm

(2014) Marta Luz et al.   PLoS One

 -Catenin Activation Regulates Tissue Growth Non-Cell Autonomously in the Hair Stem Cell Niche

(2014) E. R. Deschene et al.   SCIENCE

Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients

(2014) Cameron J. Koch et al.   Translational Oncology

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion

(2014) Ana-Citlali Gradilla et al.   Nature Communications

Tumor-Stroma Interaction: Revealing Fibroblast-Secreted Exosomes as Potent Regulators of Wnt-Planar Cell Polarity Signaling in Cancer Metastasis

(2013) V. Luga et al.   CANCER RESEARCH

A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling

(2013) Anne-Kathrin Gorny et al.   Cell Communication and Signaling

Secretion and extracellular space travel of Wnt proteins

(2013) Julia Christina Gross et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Generation and interpretation of FGF morphogen gradients in vertebrates

(2013) Christian Bökel et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Morphogen transport

(2013) P. Muller et al.   DEVELOPMENT

Patterning and growth control by membrane-tethered Wingless

(2013) Cyrille Alexandre et al.   NATURE

Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning

(2013) Timothy A. Sanders et al.   NATURE

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

(2013) Marcus Bischoff et al.   NATURE CELL BIOLOGY

A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

(2013) S. J. Habib et al.   SCIENCE

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Investigating the principles of morphogen gradient formation: from tissues to cells

(2012) Anna Kicheva et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Live imaging of active fluorophore labelled Wnt proteins

(2012) Tatjana Holzer et al.   FEBS LETTERS

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Drosophila S2 Cells Secrete Wingless on Exosome-Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

(2012) Karen Beckett et al.   TRAFFIC

Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila

(2012) Patricia Rojas-Ríos et al.   PLOS BIOLOGY

Secreted Wnt “inhibitors” are not just inhibitors: Regulation of extracellular Wnt by secreted Frizzled-related proteins

(2011) Yusuke Mii et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

(2011) K. A. Mulligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity of Drosophila Cytonemes for Distinct Signaling Pathways

(2011) S. Roy et al.   SCIENCE

Dynamic Filopodia Transmit Intermittent Delta-Notch Signaling to Drive Pattern Refinement during Lateral Inhibition

(2010) Michael Cohen et al.   DEVELOPMENTAL CELL

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

(2010) G. S. Coombs et al.   JOURNAL OF CELL SCIENCE

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless

(2009) Ceren Korkut et al.   CELL

Wingless Promotes Proliferative Growth in a Gradient-Independent Manner

(2009) L. A. Baena-Lopez et al.   Science Signaling

Mammalian Wnt3a is Released on Lipoprotein Particles

(2009) Sylvia Neumann et al.   TRAFFIC

Cellular Trafficking of the Glypican Dally-like Is Required for Full-Strength Hedgehog Signaling and Wingless Transcytosis

(2008) Armel Gallet et al.   DEVELOPMENTAL CELL

Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy

(2008) P. J. Keller et al.   SCIENCE