Our microbes not only produce antibiotics, they also overproduce amino acids

Characterization of bifunctional l-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis

(2016) Jianhua Yang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Rational design and metabolic analysis of Escherichia coli for effective production of L-tryptophan at high concentration

(2016) Lin Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhancing pentose phosphate pathway inCorynebacterium glutamicumto improve l-isoleucine production

(2016) Wenjian Ma et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Metabolic engineering ofEscherichia colifor microbial production of L-methionine

(2016) Jian-Feng Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic engineering of Escherichia coli W3110 for the production of l-methionine

(2016) Hua Li et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Reengineering of the feedback-inhibition enzyme N-acetyl-l-glutamate kinase to enhance l-arginine production in Corynebacterium crenatum

(2016) Jingjing Zhang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Efficient bioconversion of l-glutamate to γ-aminobutyric acid by Lactobacillus brevis resting cells

(2016) Xiufeng Shi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The Actinobacterium Corynebacterium glutamicum, an Industrial Workhorse

(2016) Joo-Young Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic engineering of Corynebacterium glutamicum for enhanced production of 5-aminovaleric acid

(2016) Jae Ho Shin et al.   Microbial Cell Factories

Systems metabolic engineering of Corynebacterium glutamicum for the production of the carbon-5 platform chemicals 5-aminovalerate and glutarate

(2016) Christina Maria Rohles et al.   Microbial Cell Factories

Metabolic engineering of Escherichia coli W3110 for L-homoserine production

(2016) Hua Li et al.   PROCESS BIOCHEMISTRY

Improving the Production of L-Phenylalanine by Identifying Key Enzymes Through Multi-Enzyme Reaction System in Vitro

(2016) Dongqin Ding et al.   Scientific Reports

A giant market and a powerful metabolism: l-lysine provided by Corynebacterium glutamicum

(2015) Lothar Eggeling et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Deletion of odhA or pyc improves production of γ-aminobutyric acid and its precursor l-glutamate in recombinant Corynebacterium glutamicum

(2015) Nannan Wang et al.   BIOTECHNOLOGY LETTERS

Construction of a highly efficient Bacillus subtilis 168 whole-cell biocatalyst and its application in the production of l-ornithine

(2015) Meizhou Wang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Efficient aspartic acid production by a psychrophile-based simple biocatalyst

(2015) Takahisa Tajima et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase

(2015) Dezheng Wang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Metabolic engineering of Escherichia coli for the production of 3-aminopropionic acid

(2015) Chan Woo Song et al.   METABOLIC ENGINEERING

pH stabilization of lactic acid fermentation via the glutamate decarboxylation reaction: Simultaneous production of lactic acid and γ-aminobutyric acid

(2015) Weirui Zhao et al.   PROCESS BIOCHEMISTRY

The contest for precursors: channelling l-isoleucine synthesis in Corynebacterium glutamicum without byproduct formation

(2014) Michael Vogt et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Functional expression of l-lysine α-oxidase from Scomber japonicus in Escherichia coli for one-pot synthesis of l-pipecolic acid from dl-lysine

(2014) Yasushi Tani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Application of metabolic engineering for the biotechnological production of l-valine

(2014) Marco Oldiges et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Methionine production—a critical review

(2014) Thomas Willke   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High-level production of L-threonine by recombinantEscherichia coliwith combined feeding strategies

(2014) Jian Wang et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Metabolic engineering ofCorynebacterium glutamicumfor the production of L-ornithine

(2014) Seo Yun Kim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microbial production of amino acids and derived chemicals: Synthetic biology approaches to strain development

(2014) Volker F Wendisch   CURRENT OPINION IN BIOTECHNOLOGY

Modification of glycolysis and its effect on the production of l-threonine in Escherichia coli

(2014) Xixian Xie et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Enhancement of l-ornithine production by disruption of three genes encoding putative oxidoreductases in Corynebacterium glutamicum

(2014) Gui-Hye Hwang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Improvement of l-citrulline production in Corynebacterium glutamicum by ornithine acetyltransferase

(2014) N. Hao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Metabolic engineering of microorganisms for the production of L-arginine and its derivatives

(2014) Jae Ho Shin et al.   Microbial Cell Factories

Genetic engineering of Escherichia coli to enhance production of l-tryptophan

(2013) Jian Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Knocking out analysis of tryptophan permeases in Escherichia coli for improving L-tryptophan production

(2013) Pengfei Gu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biotechnology in the Production of Pharmaceutical Industry Ingredients: Amino Acids

(2013) Kalin Ivanov et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Metabolic engineering of Corynebacterium glutamicum for increasing the production of l-ornithine by increasing NADPH availability

(2013) Ling-Yan Jiang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Enhancement of γ-aminobutyric acid production in recombinant Corynebacterium glutamicum by co-expressing two glutamate decarboxylase genes from Lactobacillus brevis

(2013) Feng Shi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Pushing product formation to its limit: Metabolic engineering of Corynebacterium glutamicum for l-leucine overproduction

(2013) Michael Vogt et al.   METABOLIC ENGINEERING

Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation

(2013) Stephan Binder et al.   NUCLEIC ACIDS RESEARCH

Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development

(2012) Judith Becker et al.   CURRENT OPINION IN BIOTECHNOLOGY

High yield and cost-effective production of poly(γ-glutamic acid) with Bacillus subtilis

(2011) Jin Huang et al.   ENGINEERING IN LIFE SCIENCES

Production of glutathione using a bifunctional enzyme encoded by gshF from Streptococcus thermophilus expressed in Escherichia coli

(2011) Wei Li et al.   JOURNAL OF BIOTECHNOLOGY

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

(2011) Judith Becker et al.   METABOLIC ENGINEERING

Taste receptors for umami: the case for multiple receptors

(2009) Nirupa Chaudhari et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Molecular mechanism for the umami taste synergism

(2008) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

L-Tyrosine production by recombinantEscherichia coli: Fermentation optimization and recovery

(2007) Ranjan Patnaik et al.   BIOTECHNOLOGY AND BIOENGINEERING