A giant market and a powerful metabolism: l-lysine provided by Corynebacterium glutamicum

Features of the biotechnologically relevant polyamide family “cyanophycins” and their biosynthesis in prokaryotes and eukaryotes

(2015) Maja Frommeyer et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

CO2/HCO3 − perturbations of simulated large scale gradients in a scale-down device cause fast transcriptional responses in Corynebacterium glutamicum

(2014) Jens Buchholz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

From zero to hero – Production of bio-based nylon from renewable resources using engineered Corynebacterium glutamicum

(2014) Stefanie Kind et al.   METABOLIC ENGINEERING

A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase

(2014) Rajesh Reddy Bommareddy et al.   METABOLIC ENGINEERING

Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum

(2013) Zhen Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic Engineering for l-Glutamine Overproduction by Using DNA Gyrase Mutations in Escherichia coli

(2013) Mikiro Hayashi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Platform Engineering of Corynebacterium glutamicum with Reduced Pyruvate Dehydrogenase Complex Activity for Improved Production of l-Lysine, l-Valine, and 2-Ketoisovalerate

(2013) Jens Buchholz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

C1Metabolism in Corynebacterium glutamicum: an Endogenous Pathway for Oxidation of Methanol to Carbon Dioxide

(2013) Sabrina Witthoff et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Assessment of robustness against dissolved oxygen/substrate oscillations for C. glutamicum DM1933 in two-compartment bioreactor

(2013) Friedrich Käß et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Complex Regulation of the Phosphoenolpyruvate Carboxykinase Gene pck and Characterization of Its GntR-Type Regulator IolR as a Repressor of myo-Inositol Utilization Genes in Corynebacterium glutamicum

(2013) S. Klaffl et al.   JOURNAL OF BACTERIOLOGY

Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation

(2013) Stephan Binder et al.   NUCLEIC ACIDS RESEARCH

Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways

(2013) Georg Schendzielorz et al.   ACS Synthetic Biology

Metabolic engineering of industrial platform microorganisms for biorefinery applications – Optimization of substrate spectrum and process robustness by rational and evolutive strategies

(2012) Nele Buschke et al.   BIORESOURCE TECHNOLOGY

Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity

(2012) Jan van Ooyen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Production of l-lysine on different silage juices using genetically engineered Corynebacterium glutamicum

(2012) Andreas Neuner et al.   JOURNAL OF BIOTECHNOLOGY

The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids

(2012) Nurije Mustafi et al.   METABOLIC ENGINEERING

Increased lysine production by flux coupling of the tricarboxylic acid cycle and the lysine biosynthetic pathway—Metabolic engineering of the availability of succinyl-CoA in Corynebacterium glutamicum

(2012) Stefanie Kind et al.   METABOLIC ENGINEERING

Phylogenetic Framework and Molecular Signatures for the Main Clades of the Phylum Actinobacteria

(2012) B. Gao et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level

(2012) Stephan Binder et al.   GENOME BIOLOGY

Accelerated pentose utilization byCorynebacterium glutamicumfor accelerated production of lysine, glutamate, ornithine and putrescine

(2012) Tobias M. Meiswinkel et al.   Microbial Biotechnology

Coevolutionary Analysis Enabled Rational Deregulation of Allosteric Enzyme Inhibition in Corynebacterium glutamicum for Lysine Production

(2011) Zhen Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phosphotransferase System-Independent Glucose Utilization in Corynebacterium glutamicum by Inositol Permeases and Glucokinases

(2011) Steffen N. Lindner et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Comparative13C Metabolic Flux Analysis of Pyruvate Dehydrogenase Complex-Deficient, l-Valine-Producing Corynebacterium glutamicum

(2011) Tobias Bartek et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum

(2011) Masato Ikeda et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

(2011) Judith Becker et al.   METABOLIC ENGINEERING

Engineering of Corynebacterium glutamicum with an NADPH-Generating Glycolytic Pathway for L-Lysine Production

(2010) S. Takeno et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Dipeptides in nutrition and therapy: cyanophycin-derived dipeptides as natural alternatives and their biotechnological production

(2010) Ahmed Sallam et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Optimization of poly-ε-lysine production by Streptomyces noursei NRRL 5126

(2010) Sandip B. Bankar et al.   BIORESOURCE TECHNOLOGY

The E2 Domain of OdhA of Corynebacterium glutamicum Has Succinyltransferase Activity Dependent on Lipoyl Residues of the Acetyltransferase AceF

(2010) M. Hoffelder et al.   JOURNAL OF BACTERIOLOGY

Reengineering of a Corynebacterium glutamicum L-Arginine and L-Citrulline Producer

(2009) M. Ikeda et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic Engineering of the Tricarboxylic Acid Cycle for Improved Lysine Production by Corynebacterium glutamicum

(2009) J. Becker et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

(2009) Hiroko Tsuruta et al.   PLoS One

Acetohydroxyacid Synthase, a Novel Target for Improvement of L-Lysine Production by Corynebacterium glutamicum

(2008) B. Blombach et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Activity of Exporters of Escherichia coli in Corynebacterium glutamicum, and Their Use to Increase L-Threonine Production

(2008) Ramon Diesveld et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Computer-aided rational design of the phosphotransferase system for enhanced glucose uptake in Escherichia coli

(2008) Yousuke Nishio et al.   Molecular Systems Biology