Application of metabolic engineering for the biotechnological production of l-valine

Looking for the pick of the bunch: high-throughput screening of producing microorganisms with biosensors

(2014) Marcus Schallmey et al.   CURRENT OPINION IN BIOTECHNOLOGY

Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains

(2014) Nurije Mustafi et al.   PLoS One

Platform Engineering of Corynebacterium glutamicum with Reduced Pyruvate Dehydrogenase Complex Activity for Improved Production of l-Lysine, l-Valine, and 2-Ketoisovalerate

(2013) Jens Buchholz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation

(2013) Stephan Binder et al.   NUCLEIC ACIDS RESEARCH

l-Valine production with minimization of by-products’ synthesis in Corynebacterium glutamicum and Brevibacterium flavum

(2012) Xiaohu Hou et al.   AMINO ACIDS

Engineering of Corynebacterium glutamicum for High-Yield l-Valine Production under Oxygen Deprivation Conditions

(2012) Satoshi Hasegawa et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bio-based production of C2-C6 platform chemicals

(2012) Yu-Sin Jang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level

(2012) Alexander Grünberger et al.   LAB ON A CHIP

Picoliter nDEP traps enable time-resolved contactless single bacterial cell analysis in controlled microenvironments

(2012) Frederik S. O. Fritzsch et al.   LAB ON A CHIP

The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids

(2012) Nurije Mustafi et al.   METABOLIC ENGINEERING

An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform

(2012) Peter Rohe et al.   Microbial Cell Factories

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level

(2012) Stephan Binder et al.   GENOME BIOLOGY

Bio-based production of organic acids withCorynebacterium glutamicum

(2012) Stefan Wieschalka et al.   Microbial Biotechnology

Improvement of the Redox Balance Increases l-Valine Production by Corynebacterium glutamicum under Oxygen Deprivation Conditions

(2011) Satoshi Hasegawa et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Comparative13C Metabolic Flux Analysis of Pyruvate Dehydrogenase Complex-Deficient, l-Valine-Producing Corynebacterium glutamicum

(2011) Tobias Bartek et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Corynebacterium glutamicum Tailored for Efficient Isobutanol Production

(2011) Bastian Blombach et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A new microfluidic concept for parallel operated milliliter-scale stirred tank bioreactors

(2011) Gabi Gebhardt et al.   BIOTECHNOLOGY PROGRESS

Determination of the fourth and fifth limiting amino acids in broilers fed on diets containing maize, soybean meal and poultry by-product meal from 28 to 42 d of age

(2011) W.A. Dozier III et al.   BRITISH POULTRY SCIENCE

Branched-chain amino acids as pharmacological nutrients in chronic liver disease

(2011) Takumi Kawaguchi et al.   HEPATOLOGY

Maximizing the use of supplemental amino acids in corn-soybean meal diets for 20- to 45-kilogram pigs1,2

(2011) M. L. Roux et al.   JOURNAL OF ANIMAL SCIENCE

Lrp of Corynebacterium glutamicum controls expression of the brnFE operon encoding the export system for l-methionine and branched-chain amino acids

(2011) Christian Lange et al.   JOURNAL OF BIOTECHNOLOGY

Improvement of l-valine production at high temperature in Brevibacterium flavum by overexpressing ilvEBNrC genes

(2011) Xiaohu Hou et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Metabolic Engineering of Corynebacterium glutamicum for 2-Ketoisovalerate Production

(2010) F. S. Krause et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Studies on substrate utilisation in l-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex

(2010) Tobias Bartek et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Microfluidic biolector-microfluidic bioprocess control in microtiter plates

(2010) Matthias Funke et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fed-batch culture of Escherichia coli for L-valine production based on in silico flux response analysis

(2010) Jin Hwan Park et al.   BIOTECHNOLOGY AND BIOENGINEERING

Escherichia coli W as a new platform strain for the enhanced production of L-Valine by systems metabolic engineering

(2010) Jin Hwan Park et al.   BIOTECHNOLOGY AND BIOENGINEERING

Flow cytometry for bacteria: enabling metabolic engineering, synthetic biology and the elucidation of complex phenotypes

(2010) Bryan P Tracy et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biofuels: Biomolecular Engineering Fundamentals and Advances

(2010) Han Li et al.   Annual Review of Chemical and Biomolecular Engineering

Increased Glucose Utilization in Corynebacterium glutamicum by Use of Maltose, and Its Application for the Improvement of L-Valine Productivity

(2009) F. S. Krause et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fermentative production of branched chain amino acids: a focus on metabolic engineering

(2009) Jin Hwan Park et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The identification of enzyme targets for the optimization of a valine producingCorynebacterium glutamicumstrain using a kinetic model

(2009) Jørgen Barsett Magnus et al.   BIOTECHNOLOGY PROGRESS

Acetohydroxyacid Synthase, a Novel Target for Improvement of L-Lysine Production by Corynebacterium glutamicum

(2008) B. Blombach et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

L-Valine Production during Growth of Pyruvate Dehydrogenase Complex- Deficient Corynebacterium glutamicum in the Presence of Ethanol or by Inactivation of the Transcriptional Regulator SugR

(2008) B. Blombach et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic Function of Corynebacterium glutamicum Aminotransferases AlaT and AvtA and Impact on L-Valine Production

(2008) J. Marienhagen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Corynebacterium glutamicum tailored for high-yield L-valine production

(2008) Bastian Blombach et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Influence of l-isoleucine and pantothenate auxotrophy for l-valine formation in Corynebacterium glutamicum revisited by metabolome analyses

(2008) Tobias Bartek et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Enhanced Valine Production inCorynebacterium glutamicumwith Defective H+-ATPase and C-Terminal Truncated Acetohydroxyacid Synthase

(2008) Masaru WADA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The standardized ileal digestible valine-to-lysine requirement ratio is at least seventy percent in postweaned piglets1

(2008) R. Barea et al.   JOURNAL OF ANIMAL SCIENCE

Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation

(2008) Jiří Holátko et al.   JOURNAL OF BIOTECHNOLOGY