Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer’s Disease
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer’s Disease
Authors
Keywords
-
Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 57, Issue 4, Pages 1071-1086
Publisher
IOS Press
Online
2016-09-20
DOI
10.3233/jad-160702
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Oxidative Stress in Diabetes and Alzheimer's Disease
- (2017) V. Prakash Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline
- (2017) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons
- (2017) Maria Manczak et al. JOURNAL OF ALZHEIMERS DISEASE
- Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins?
- (2016) Virpi Talman et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Mitochondrial Respiration in the Platelets of Patients with Alzheimer’s Disease
- (2016) Zden|k FiŠar et al. Current Alzheimer Research
- Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease
- (2016) Lu Wang et al. PLoS One
- Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease
- (2016) Simon J. Beck et al. Nature Communications
- Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders
- (2016) Freddy Jeanneteau et al. NEURAL PLASTICITY
- Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease
- (2016) Liang Zhang et al. Scientific Reports
- Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore
- (2015) Manuel Gutiérrez-Aguilar et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Treatment Options in Alzheimer´s Disease: The GABA Story
- (2015) Maite Solas et al. CURRENT PHARMACEUTICAL DESIGN
- Neurotransmitters and Novelty: A Systematic Review
- (2015) Mauricio Rangel-Gomez et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment
- (2015) Sylvia Lombardo et al. NEUROPHARMACOLOGY
- Memantine for treatment of moderate or severe Alzheimer’s disease patients in urban China: clinical and economic outcomes from a health economic model
- (2015) Shanlian Hu et al. Expert Review of Pharmacoeconomics & Outcomes Research
- Calcium/calmodulin-dependent kinase II and Alzheimer’s disease
- (2015) Anshua Ghosh et al. Molecular Brain
- Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice
- (2015) Lin Lu et al. PLoS One
- Misfolded proteins, mitochondrial dysfunction, and neurodegenerative diseases
- (2014) P. Hemachandra Reddy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Efficacy and safety of memantine in patients with moderate-to-severe Alzheimer's disease: results of a pooled analysis of two randomized, double-blind, placebo-controlled trials in Japan
- (2014) Yu Nakamura et al. EXPERT OPINION ON PHARMACOTHERAPY
- Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer’s Disease: Understanding the Therapeutics Strategies
- (2014) Pradip K. Kamat et al. MOLECULAR NEUROBIOLOGY
- An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
- (2014) K. N. Alavian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DRD2 genotype predicts prefrontal activity during working memory after stimulation of D2 receptors with bromocriptine
- (2014) Barbara Gelao et al. PSYCHOPHARMACOLOGY
- Rescue of tau-induced synaptic transmission pathology by paclitaxel
- (2014) Hadas Erez et al. Frontiers in Cellular Neuroscience
- M1 muscarinic acetylcholine receptor in Alzheimer’s disease
- (2014) Shangtong Jiang et al. Neuroscience Bulletin
- “Is dopamine involved in Alzheimer's disease?â€
- (2014) Alessandro Martorana et al. Frontiers in Aging Neuroscience
- Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration
- (2013) Heng Du et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- N-Methyl D-Aspartate (NMDA) Receptor Antagonists and Memantine Treatment for Alzheimer’s Disease, Vascular Dementia and Parkinson’s Disease
- (2013) David Olivares et al. Current Alzheimer Research
- Memantine in Patients with Moderate to Severe Alzheimer's Disease: Meta-Analyses Using Realistic Definitions of Response
- (2013) David Wilkinson et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease
- (2013) Bruce J. Melancon et al. DRUG DISCOVERY TODAY
- Differential requirement for NMDAR activity in SAP97β-mediated regulation of the number and strength of glutamatergic AMPAR-containing synapses
- (2013) Mingna Liu et al. JOURNAL OF NEUROPHYSIOLOGY
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Steroid hormone synthesis in mitochondria
- (2013) Walter L. Miller MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons
- (2013) Lan Guo et al. PLoS One
- Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain
- (2013) Efrat Kravitz et al. PLoS One
- Dimers of mitochondrial ATP synthase form the permeability transition pore
- (2013) V. Giorgio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Regulation of presynaptic calcium in a mammalian synaptic terminal
- (2012) Qun-Fang Wan et al. JOURNAL OF NEUROPHYSIOLOGY
- Dopamine boosts ageing memories
- (2012) Sian Lewis NATURE REVIEWS NEUROSCIENCE
- Synapses and Alzheimer's Disease
- (2012) M. Sheng et al. Cold Spring Harbor Perspectives in Biology
- Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer’s Disease
- (2012) Wendou Yu et al. NEURAL PLASTICITY
- Brain Glutamate Levels Are Decreased in Alzheimer’s Disease
- (2011) Nicolas Fayed et al. American Journal of Alzheimers Disease and Other Dementias
- Synaptic Mitochondrial Pathology in Alzheimer's Disease
- (2011) Heng Du et al. ANTIOXIDANTS & REDOX SIGNALING
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Brain aging, Alzheimer's disease, and mitochondria
- (2011) Russell H. Swerdlow BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
- (2011) P. Hemachandra Reddy BRAIN RESEARCH
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer’s disease
- (2011) Tao Ma et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid -Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide
- (2011) T. Ma et al. JOURNAL OF NEUROSCIENCE
- PKC Activation Prevents Synaptic Loss, A Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
- (2011) J. Hongpaisan et al. JOURNAL OF NEUROSCIENCE
- Alzheimer's disease: synapses gone cold
- (2011) Robert M Koffie et al. Molecular Neurodegeneration
- Regulation of axonal mitochondrial transport and its impact on synaptic transmission
- (2011) Qian Cai et al. NEUROSCIENCE RESEARCH
- Tyrosine hydroxylase and regulation of dopamine synthesis
- (2010) S. Colette Daubner et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The cholinergic system in aging and neuronal degeneration
- (2010) Reinhard Schliebs et al. BEHAVIOURAL BRAIN RESEARCH
- Mitochondrial Ca2+ channels: Great unknowns with important functions
- (2010) Roland Malli et al. FEBS LETTERS
- Mitochondrial medicine for neurodegenerative diseases
- (2010) Heng Du et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61
- (2010) P. Kurup et al. JOURNAL OF NEUROSCIENCE
- Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis
- (2010) G.A. Scullion et al. NEUROPHARMACOLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Brain fuel metabolism, aging, and Alzheimer’s disease
- (2010) Stephen Cunnane et al. NUTRITION
- Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
- (2010) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characteristics and possible functions of mitochondrial Ca2+ transport mechanisms
- (2009) Thomas E. Gunter et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondria: A therapeutic target in neurodegeneration
- (2009) Paula I. Moreira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Release of Adenosine and ATP During Ischemia and Epilepsy
- (2009) Nicholas Dale et al. Current Neuropharmacology
- Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer’s disease
- (2009) Magali Dumont et al. FASEB JOURNAL
- β-Amyloid Causes Depletion of Synaptic Vesicles Leading to Neurotransmission Failure
- (2009) Jorge Parodi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
- (2009) Heng Du et al. NEUROBIOLOGY OF AGING
- A novel mechanism for GABA synthesis and packaging into synaptic vesicles
- (2009) Chandana Buddhala et al. NEUROCHEMISTRY INTERNATIONAL
- Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
- (2009) Shaomin Li et al. NEURON
- Dopamine Modulates Cholinergic Cortical Excitability in Alzheimer's Disease Patients
- (2009) Alessandro Martorana et al. NEUROPSYCHOPHARMACOLOGY
- Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
- (2009) C. A. Massaad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
- (2009) Dong-Hyung Cho et al. SCIENCE
- Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
- (2008) Dennis J. Selkoe BEHAVIOURAL BRAIN RESEARCH
- Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia
- (2008) Christof Grewer et al. IUBMB LIFE
- Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids
- (2008) J. Kalervo Hiltunen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
- (2008) Heng Du et al. NATURE MEDICINE
- Memory loss caused by β-amyloid protein is rescued by a β3-adrenoceptor agonist
- (2008) Marie E. Gibbs et al. NEUROBIOLOGY OF AGING
- Mitochondrial Medicine for Aging and Neurodegenerative Diseases
- (2008) P. Hemachandra Reddy NEUROMOLECULAR MEDICINE
- Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti–Alzheimer's disease drugs
- (2008) G.-R. Zhang et al. NEUROSCIENCE
- Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs
- (2008) Sara Sanz-Blasco et al. PLoS One
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
- Amyloid beta peptides and glutamatergic synaptic dysregulation
- (2007) Kodeeswaran Parameshwaran et al. EXPERIMENTAL NEUROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now