标题
Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer’s Disease
作者
关键词
-
出版物
JOURNAL OF ALZHEIMERS DISEASE
Volume 57, Issue 4, Pages 1071-1086
出版商
IOS Press
发表日期
2016-09-20
DOI
10.3233/jad-160702
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Oxidative Stress in Diabetes and Alzheimer's Disease
- (2017) V. Prakash Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline
- (2017) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons
- (2017) Maria Manczak et al. JOURNAL OF ALZHEIMERS DISEASE
- Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins?
- (2016) Virpi Talman et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Mitochondrial Respiration in the Platelets of Patients with Alzheimer’s Disease
- (2016) Zden|k FiŠar et al. Current Alzheimer Research
- Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease
- (2016) Lu Wang et al. PLoS One
- Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease
- (2016) Simon J. Beck et al. Nature Communications
- Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders
- (2016) Freddy Jeanneteau et al. NEURAL PLASTICITY
- Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease
- (2016) Liang Zhang et al. Scientific Reports
- Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore
- (2015) Manuel Gutiérrez-Aguilar et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Treatment Options in Alzheimer´s Disease: The GABA Story
- (2015) Maite Solas et al. CURRENT PHARMACEUTICAL DESIGN
- Neurotransmitters and Novelty: A Systematic Review
- (2015) Mauricio Rangel-Gomez et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment
- (2015) Sylvia Lombardo et al. NEUROPHARMACOLOGY
- Memantine for treatment of moderate or severe Alzheimer’s disease patients in urban China: clinical and economic outcomes from a health economic model
- (2015) Shanlian Hu et al. Expert Review of Pharmacoeconomics & Outcomes Research
- Calcium/calmodulin-dependent kinase II and Alzheimer’s disease
- (2015) Anshua Ghosh et al. Molecular Brain
- Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice
- (2015) Lin Lu et al. PLoS One
- Misfolded proteins, mitochondrial dysfunction, and neurodegenerative diseases
- (2014) P. Hemachandra Reddy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Efficacy and safety of memantine in patients with moderate-to-severe Alzheimer's disease: results of a pooled analysis of two randomized, double-blind, placebo-controlled trials in Japan
- (2014) Yu Nakamura et al. EXPERT OPINION ON PHARMACOTHERAPY
- Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer’s Disease: Understanding the Therapeutics Strategies
- (2014) Pradip K. Kamat et al. MOLECULAR NEUROBIOLOGY
- An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
- (2014) K. N. Alavian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DRD2 genotype predicts prefrontal activity during working memory after stimulation of D2 receptors with bromocriptine
- (2014) Barbara Gelao et al. PSYCHOPHARMACOLOGY
- Rescue of tau-induced synaptic transmission pathology by paclitaxel
- (2014) Hadas Erez et al. Frontiers in Cellular Neuroscience
- M1 muscarinic acetylcholine receptor in Alzheimer’s disease
- (2014) Shangtong Jiang et al. Neuroscience Bulletin
- “Is dopamine involved in Alzheimer's disease?â€
- (2014) Alessandro Martorana et al. Frontiers in Aging Neuroscience
- Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration
- (2013) Heng Du et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- N-Methyl D-Aspartate (NMDA) Receptor Antagonists and Memantine Treatment for Alzheimer’s Disease, Vascular Dementia and Parkinson’s Disease
- (2013) David Olivares et al. Current Alzheimer Research
- Memantine in Patients with Moderate to Severe Alzheimer's Disease: Meta-Analyses Using Realistic Definitions of Response
- (2013) David Wilkinson et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease
- (2013) Bruce J. Melancon et al. DRUG DISCOVERY TODAY
- Differential requirement for NMDAR activity in SAP97β-mediated regulation of the number and strength of glutamatergic AMPAR-containing synapses
- (2013) Mingna Liu et al. JOURNAL OF NEUROPHYSIOLOGY
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Steroid hormone synthesis in mitochondria
- (2013) Walter L. Miller MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons
- (2013) Lan Guo et al. PLoS One
- Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain
- (2013) Efrat Kravitz et al. PLoS One
- Dimers of mitochondrial ATP synthase form the permeability transition pore
- (2013) V. Giorgio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Regulation of presynaptic calcium in a mammalian synaptic terminal
- (2012) Qun-Fang Wan et al. JOURNAL OF NEUROPHYSIOLOGY
- Dopamine boosts ageing memories
- (2012) Sian Lewis NATURE REVIEWS NEUROSCIENCE
- Synapses and Alzheimer's Disease
- (2012) M. Sheng et al. Cold Spring Harbor Perspectives in Biology
- Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer’s Disease
- (2012) Wendou Yu et al. NEURAL PLASTICITY
- Brain Glutamate Levels Are Decreased in Alzheimer’s Disease
- (2011) Nicolas Fayed et al. American Journal of Alzheimers Disease and Other Dementias
- Synaptic Mitochondrial Pathology in Alzheimer's Disease
- (2011) Heng Du et al. ANTIOXIDANTS & REDOX SIGNALING
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Brain aging, Alzheimer's disease, and mitochondria
- (2011) Russell H. Swerdlow BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
- (2011) P. Hemachandra Reddy BRAIN RESEARCH
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer’s disease
- (2011) Tao Ma et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid -Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide
- (2011) T. Ma et al. JOURNAL OF NEUROSCIENCE
- PKC Activation Prevents Synaptic Loss, A Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
- (2011) J. Hongpaisan et al. JOURNAL OF NEUROSCIENCE
- Alzheimer's disease: synapses gone cold
- (2011) Robert M Koffie et al. Molecular Neurodegeneration
- Regulation of axonal mitochondrial transport and its impact on synaptic transmission
- (2011) Qian Cai et al. NEUROSCIENCE RESEARCH
- Tyrosine hydroxylase and regulation of dopamine synthesis
- (2010) S. Colette Daubner et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The cholinergic system in aging and neuronal degeneration
- (2010) Reinhard Schliebs et al. BEHAVIOURAL BRAIN RESEARCH
- Mitochondrial Ca2+ channels: Great unknowns with important functions
- (2010) Roland Malli et al. FEBS LETTERS
- Mitochondrial medicine for neurodegenerative diseases
- (2010) Heng Du et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61
- (2010) P. Kurup et al. JOURNAL OF NEUROSCIENCE
- Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis
- (2010) G.A. Scullion et al. NEUROPHARMACOLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Brain fuel metabolism, aging, and Alzheimer’s disease
- (2010) Stephen Cunnane et al. NUTRITION
- Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
- (2010) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characteristics and possible functions of mitochondrial Ca2+ transport mechanisms
- (2009) Thomas E. Gunter et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondria: A therapeutic target in neurodegeneration
- (2009) Paula I. Moreira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Release of Adenosine and ATP During Ischemia and Epilepsy
- (2009) Nicholas Dale et al. Current Neuropharmacology
- Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer’s disease
- (2009) Magali Dumont et al. FASEB JOURNAL
- β-Amyloid Causes Depletion of Synaptic Vesicles Leading to Neurotransmission Failure
- (2009) Jorge Parodi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
- (2009) Heng Du et al. NEUROBIOLOGY OF AGING
- A novel mechanism for GABA synthesis and packaging into synaptic vesicles
- (2009) Chandana Buddhala et al. NEUROCHEMISTRY INTERNATIONAL
- Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
- (2009) Shaomin Li et al. NEURON
- Dopamine Modulates Cholinergic Cortical Excitability in Alzheimer's Disease Patients
- (2009) Alessandro Martorana et al. NEUROPSYCHOPHARMACOLOGY
- Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
- (2009) C. A. Massaad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
- (2009) Dong-Hyung Cho et al. SCIENCE
- Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
- (2008) Dennis J. Selkoe BEHAVIOURAL BRAIN RESEARCH
- Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia
- (2008) Christof Grewer et al. IUBMB LIFE
- Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids
- (2008) J. Kalervo Hiltunen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
- (2008) Heng Du et al. NATURE MEDICINE
- Memory loss caused by β-amyloid protein is rescued by a β3-adrenoceptor agonist
- (2008) Marie E. Gibbs et al. NEUROBIOLOGY OF AGING
- Mitochondrial Medicine for Aging and Neurodegenerative Diseases
- (2008) P. Hemachandra Reddy NEUROMOLECULAR MEDICINE
- Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti–Alzheimer's disease drugs
- (2008) G.-R. Zhang et al. NEUROSCIENCE
- Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs
- (2008) Sara Sanz-Blasco et al. PLoS One
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
- Amyloid beta peptides and glutamatergic synaptic dysregulation
- (2007) Kodeeswaran Parameshwaran et al. EXPERIMENTAL NEUROLOGY
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