Dickkopf 3 (Dkk3) Improves Amyloid-β Pathology, Cognitive Dysfunction, and Cerebral Glucose Metabolism in a Transgenic Mouse Model of Alzheimer’s Disease

The Role of ADAM10 in Alzheimer’s Disease

(2017) Xiang-Zhen Yuan et al.   JOURNAL OF ALZHEIMERS DISEASE

Activation of GSK-3 disrupts cholinergic homoeostasis in nucleus basalis of Meynert and frontal cortex of rats

(2017) Yue Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Temporal lobe in human aging: A quantitative protein profiling study of samples from Chinese Human Brain Bank

(2016) Benhong Xu et al.   EXPERIMENTAL GERONTOLOGY

PKC Activation Counteracts ADAM10 Deficit in HuD-Silenced Neuroblastoma Cells

(2016) Nicoletta Marchesi et al.   JOURNAL OF ALZHEIMERS DISEASE

DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity

(2016) Lanfeng Xie et al.   JOURNAL OF HEPATOLOGY

Quantitative protein profiling of hippocampus during human aging

(2016) Benhong Xu et al.   NEUROBIOLOGY OF AGING

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction

(2015) Ming-Wei Bao et al.   BASIC RESEARCH IN CARDIOLOGY

Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer’s disease

(2015) Jesper Riise et al.   JOURNAL OF NEURAL TRANSMISSION

Dkk3 prevents familial dilated cardiomyopathy development through Wnt pathway

(2015) Dan Lu et al.   LABORATORY INVESTIGATION

Downregulation of canonical Wnt signaling in hippocampus of SAMP8 mice

(2015) Sergi Bayod et al.   NEUROBIOLOGY OF AGING

Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease

(2015) Nana Jin et al.   Scientific Reports

Dickkopf-3, a Tissue-Derived Modulator of Local T-Cell Responses

(2015) Michael Meister et al.   Frontiers in Immunology

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In vivo Activation of Wnt Signaling Pathway Enhances Cognitive Function of Adult Mice and Reverses Cognitive Deficits in an Alzheimer's Disease Model

(2014) J. Y. Vargas et al.   JOURNAL OF NEUROSCIENCE

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Early detection of Alzheimer's disease using PiB and FDG PET

(2014) Ann D. Cohen et al.   NEUROBIOLOGY OF DISEASE

SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation

(2014) C Saraceno et al.   Cell Death & Disease

Wnt/β-catenin signalling: from plasma membrane to nucleus

(2013) Wantae Kim et al.   BIOCHEMICAL JOURNAL

Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

(2013) Dong-Mei Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetic Silencing of DKK3 in Medulloblastoma

(2013) Francesca Valdora et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

(2013) Georges Mairet-Coello et al.   NEURON

Glycogen synthase kinase-3 reduces acetylcholine level in striatum via disturbing cellular distribution of choline acetyltransferase in cholinergic interneurons in rats

(2013) L. Zhao et al.   NEUROSCIENCE

Cardiotrophin-1 (CTF1) ameliorates glucose-uptake defects and improves memory and learning deficits in a transgenic mouse model of Alzheimer's disease

(2013) Dongmei Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics

(2013) Carmen Silva-Alvarez et al.   Frontiers in Cellular Neuroscience

Regional and cell-type specific distribution of HDAC2 in the adult mouse brain

(2012) Zhi-Gang Yao et al.   Brain Structure & Function

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

(2012) Nibaldo C. Inestrosa et al.   Journal of Neuroimmune Pharmacology

Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer's disease

(2012) Dongmei Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons

(2011) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-29c regulates BACE1 protein expression

(2011) Yuanyuan Zong et al.   BRAIN RESEARCH

AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of β-catenin at Ser 552

(2010) Junxing Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt Trafficking: New Insights into Wnt Maturation, Secretion and Spreading

(2010) Fillip Port et al.   TRAFFIC

Spatial navigation testing discriminates two types of amnestic mild cognitive impairment

(2009) Jan Laczó et al.   BEHAVIOURAL BRAIN RESEARCH

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells

(2009) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

(2009) E M Toledo et al.   MOLECULAR PSYCHIATRY

Wnt signaling in Alzheimer's disease: Up or down, that is the question

(2008) Rick A.C.M. Boonen et al.   AGEING RESEARCH REVIEWS

Leptin reduces Alzheimer’s disease-related tau phosphorylation in neuronal cells

(2008) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increase of Dkk-3 blood plasma levels in the elderly

(2008) Christoph Zenzmaier et al.   EXPERIMENTAL GERONTOLOGY

Dkk3, downregulated in cervical cancer, functions as a negative regulator of β-catenin

(2008) Eun-Ju Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Apolipoprotein E, Amyloid-β, and Blood-Brain Barrier Permeability in Alzheimer Disease

(2008) John E. Donahue et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Musashi1 Modulates Mammary Progenitor Cell Expansion through Proliferin-Mediated Activation of the Wnt and Notch Pathways

(2008) X.-Y. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY