SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation

Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer’s disease

(2013) Elena Marcello et al.   JOURNAL OF CLINICAL INVESTIGATION

ADAM10 Prodomain Mutations Cause Late-Onset Alzheimer’s Disease: Not Just the Latest FAD

(2013) Robert Vassar   NEURON

ADAM10 Missense Mutations Potentiate β-Amyloid Accumulation by Impairing Prodomain Chaperone Function

(2013) Jaehong Suh et al.   NEURON

Genetic insights in Alzheimer's disease

(2012) Karolien Bettens et al.   LANCET NEUROLOGY

Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules

(2011) Jinwei Zhu et al.   EMBO JOURNAL

Protein Kinase Cα Promotes Cell Migration through a PDZ-Dependent Interaction with its Novel Substrate Discs Large Homolog 1 (DLG1)

(2011) Audrey K. O'Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer’s disease

(2010) Roberta Epis et al.   BRAIN

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

An Arginine Stretch Limits ADAM10 Exit from the Endoplasmic Reticulum

(2010) Elena Marcello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic Localization and Activity of ADAM10 Regulate Excitatory Synapses through N-Cadherin Cleavage

(2010) M. Malinverno et al.   JOURNAL OF NEUROSCIENCE

SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus

(2010) Elena Marcello et al.   NEUROBIOLOGY OF AGING

ADAM-10-Mediated N-Cadherin Cleavage Is Protein Kinase C-  Dependent and Promotes Glioblastoma Cell Migration

(2009) Z. A. Kohutek et al.   JOURNAL OF NEUROSCIENCE

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

(2009) Okunola Jeyifous et al.   NATURE NEUROSCIENCE