Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models

PPARγ Agonist Curcumin Reduces the Amyloid-β-Stimulated Inflammatory Responses in Primary Astrocytes

(2017) Hong-Mei Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

A computational model to predict the immune system activation by citrus-derived vaccine adjuvants

(2016) Francesco Pappalardo et al.   BIOINFORMATICS

Pim1 inhibition as a novel therapeutic strategy for Alzheimer’s disease

(2016) Ramon Velazquez et al.   Molecular Neurodegeneration

Computable cause-and-effect models of healthy and Alzheimer's disease states and their mechanistic differential analysis

(2015) Alpha Tom Kodamullil et al.   Alzheimers & Dementia

Rodent models of neuroinflammation for Alzheimer’s disease

(2015) Amir Nazem et al.   Journal of Neuroinflammation

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease

(2015) Auriel A. Willette et al.   JAMA Neurology

Neuroinflammation in Alzheimer’s Disease: from Pathogenesis to a Therapeutic Target

(2014) Sanjay W. Pimplikar   JOURNAL OF CLINICAL IMMUNOLOGY

Modulation of inflammation in transgenic models of Alzheimer’s disease

(2014) Amy M Birch et al.   Journal of Neuroinflammation

Transcriptional landscape of the prenatal human brain

(2014) Jeremy A. Miller et al.   NATURE

Genomic responses in mouse models greatly mimic human inflammatory diseases

(2014) Keizo Takao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice are not men

(2014) H. Shaw Warren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberous Sclerosis Protein 2 (TSC2) Modulates CCN4 Cytoprotection During Apoptotic Amyloid Toxicity in Microglia

(2013) Yan Chen Shang et al.   CURRENT NEUROVASCULAR RESEARCH

Rheb GTPase Regulates β-Secretase Levels and Amyloid β Generation

(2013) Neelam Shahani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From integrative disease modeling to predictive, preventive, personalized and participatory (P4) medicine

(2013) Erfan Younesi et al.   EPMA Journal

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

(2012) Y. Kawano et al.   DIABETES

Intracellular Aβ-oligomers and early inflammation in a model of Alzheimer's disease

(2011) Maria Teresa Ferretti et al.   NEUROBIOLOGY OF AGING

PPARδ Activation Acts Cooperatively with 3-Phosphoinositide-Dependent Protein Kinase-1 to Enhance Mammary Tumorigenesis

(2011) Claire B. Pollock et al.   PLoS One

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Transgenic Mouse Models of Alzheimer's Disease

(2010) Gregory A. Elder et al.   MOUNT SINAI JOURNAL OF MEDICINE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice

(2009) X. Zhang et al.   NEUROSCIENCE

Role of Tuberin in Neuronal Degeneration

(2008) Samy L. Habib et al.   NEUROCHEMICAL RESEARCH