Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2

The regulation of autophagy by calcium signals: Do we have a consensus?

(2018) Martin D. Bootman et al.   CELL CALCIUM

Antioxidant and Osmoprotecting Activity of Taurine in Dry Eye Models

(2018) Claudio Bucolo et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell

(2017) Lei Lei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells

(2017) Kwang-Youn Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Joint Survival Analysis and Clinical Outcome of Total Joint Arthroplasties With the ARPE Implant in the Treatment of Trapeziometacarpal Osteoarthritis With a Minimal Follow-Up of 5 Years

(2017) Katrien Cootjans et al.   JOURNAL OF HAND SURGERY-AMERICAN VOLUME

Single-Prolonged-Stress-Induced Changes in Autophagy-Related Proteins Beclin-1, LC3, and p62 in the Medial Prefrontal Cortex of Rats with Post-traumatic Stress Disorder

(2017) Shilei Zheng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Roles of p62 in BDNF-dependent autophagy suppression and neuroprotection against mitochondrial dysfunction in rat cortical neurons

(2017) Chia-Lin Wu et al.   JOURNAL OF NEUROCHEMISTRY

The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex

(2017) Siyu Wang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Effects of bevacizumab on endoplasmic reticulum stress in hypoxic retinal pigment epithelial cells

(2017) Joo-Hee Park et al.   PLoS One

Japanese encephalitis virus induces human neural stem/progenitor cell death by elevating GRP78, PHB and hnRNPC through ER stress

(2017) Sriparna Mukherjee et al.   Cell Death & Disease

Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway

(2017) Yun-Feng Fu et al.   Oncotarget

Effects of Chinese herbal medicines on the occurrence of diabetic retinopathy in type 2 diabetes patients and protection of ARPE-19 retina cells by inhibiting oxidative stress

(2017) Fuu-Jen Tsai et al.   Oncotarget

Decreased calpain activity in chronic myeloid leukemia impairs apoptosis by increasing survivin in myeloid progenitors and xiap1 in differentiating granulocytes

(2017) Weiqi Huang et al.   Oncotarget

Autophagy substrate SQSTM1/p62 regulates chromatin ubiquitination during the DNA damage response

(2016) Yanan Wang et al.   Autophagy

The cellular autophagy/apoptosis checkpoint during inflammation

(2016) Jeannette S. Messer   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of phagocytic activity of ARPE-19 cells by free radical mediated oxidative stress

(2016) Magdalena M. Olchawa et al.   FREE RADICAL RESEARCH

Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine Differentiated RGC-5 Retinal Ganglion Cells

(2016) Dan-dan Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

p62 improves AD-like pathology by increasing autophagy

(2016) A Caccamo et al.   MOLECULAR PSYCHIATRY

Calpain-1 and calpain-2 play opposite roles in retinal ganglion cell degeneration induced by retinal ischemia/reperfusion injury

(2016) Yubin Wang et al.   NEUROBIOLOGY OF DISEASE

Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury

(2016) Alicia K. Au et al.   Neurocritical Care

Clinical and Pathological Significance of ER Stress Marker (BiP/GRP78 and PERK) Expression in Malignant Melanoma

(2016) Akira Shimizu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

(2016) Xin-Shuang Yu et al.   Oncotarget

The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway

(2016) Lianghu Tang et al.   Scientific Reports

Propofol Decreases Endoplasmic Reticulum Stress–Mediated Apoptosis in Retinal Pigment Epithelial Cells

(2016) Xuezhi Zhou et al.   PLoS One

RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy

(2015) Qi Luan et al.   Autophagy

PERK pathway is involved in oxygen-glucose-serum deprivation-induced NF-kB activation via ROS generation in spinal cord astrocytes

(2015) Jinbo Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress

(2015) Huanqi Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Advanced glycation end-product (AGE) induces apoptosis in human retinal ARPE-19 cells via promoting mitochondrial dysfunction and activating the Fas-FasL signaling

(2015) Pu Wang et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Ethambutol induces impaired autophagic flux and apoptosis in the rat retina

(2015) S.-P. Huang et al.   Disease Models & Mechanisms

Endoplasmic reticulum stress as a novel target to ameliorate epithelial-to-mesenchymal transition and apoptosis of human peritoneal mesothelial cells

(2015) Hyun-Soo Shin et al.   LABORATORY INVESTIGATION

Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation

(2015) Changchang Liu et al.   Molecular Cancer

Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress

(2015) S Xu et al.   Cell Death & Disease

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Computational Model of Ca2+ Wave Propagation in Human Retinal Pigment Epithelial ARPE-19 Cells

(2015) Iina Vainio et al.   PLoS One

Taurine: The comeback of a neutraceutical in the prevention of retinal degenerations

(2014) Nicolas Froger et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Activation of NADPH Oxidase 4 in the Endoplasmic Reticulum Promotes Cardiomyocyte Autophagy and Survival During Energy Stress Through the Protein Kinase RNA-Activated-Like Endoplasmic Reticulum Kinase/Eukaryotic Initiation Factor 2α/Activating Transcription Factor 4 Pathway

(2013) Sebastiano Sciarretta et al.   CIRCULATION RESEARCH

Distinct Roles for  -Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration

(2013) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Free Fatty Acid Induces Endoplasmic Reticulum Stress and Apoptosis of β-cells by Ca2+/Calpain-2 Pathways

(2013) Wei Cui et al.   PLoS One

Calpain, Atg5 and Bak play important roles in the crosstalk between apoptosis and autophagy induced by influx of extracellular calcium

(2012) Mei Shi et al.   APOPTOSIS

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

(2012) Michael H. Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

ER Stress, Mitochondrial Dysfunction and Calpain/JNK Activation are Involved in Oligodendrocyte Precursor Cell Death by Unconjugated Bilirubin

(2012) Andreia Barateiro et al.   NEUROMOLECULAR MEDICINE

Human U87 Astrocytoma Cell Invasion Induced by Interaction of βig-h3 with Integrin α5β1 Involves Calpain-2

(2012) Jie Ma et al.   PLoS One

Taurine Provides Neuroprotection against Retinal Ganglion Cell Degeneration

(2012) Nicolas Froger et al.   PLoS One

Salusins protect myocardium against ischemic injury by alleviating endoplasmic reticulum stress

(2012) JianFei Wang et al.   Science China-Life Sciences

Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway

(2012) Yan Li et al.   TOXICOLOGY LETTERS

Dissecting the retinoid-induced differentiation of F9 embryonal stem cells by integrative genomics

(2011) M. A. Mendoza-Parra et al.   Molecular Systems Biology

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

(2011) R Russo et al.   Cell Death & Disease

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Control of basal autophagy by calpain1 mediated cleavage of ATG5

(2010) Hong-Guang Xia et al.   Autophagy

Mechanism of Autophagy to Apoptosis Switch Triggered in Prostate Cancer Cells by Antitumor Cytokine Melanoma Differentiation-Associated Gene 7/Interleukin-24

(2010) Sujit K. Bhutia et al.   CANCER RESEARCH

NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis

(2010) Gang Li et al.   JOURNAL OF CELL BIOLOGY

EIF2α and caspase-12 activation are involved in oxygen–glucose–serum deprivation/restoration-induced apoptosis of spinal cord astrocytes

(2010) Ailiang Zhang et al.   NEUROSCIENCE LETTERS

Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction

(2009) Ka Chen et al.   BRAIN RESEARCH