ER Stress, Mitochondrial Dysfunction and Calpain/JNK Activation are Involved in Oligodendrocyte Precursor Cell Death by Unconjugated Bilirubin

Oligodendrocyte Progenitor Cells Proliferate and Survive in an Immature State Following Treatment with an Axolemma-Enriched Fraction

(2011) Sara G Becker-Catania et al.   ASN Neuro

Enhancing remyelination in disease--can we wrap it up?

(2011) M. R. Kotter et al.   BRAIN

Elevated Levels of Bilirubin and Long-Term Exposure Impair Human Brain Microvascular Endothelial Cell Integrity

(2011) Ines Palmela et al.   CURRENT NEUROVASCULAR RESEARCH

Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin

(2011) Ana R. Vaz et al.   EXPERIMENTAL NEUROLOGY

Protein folding and the order/disorder paradox

(2011) Prakash Kulkarni et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The critical role of JNK in the ER-mitochondrial crosstalk during apoptotic cell death

(2011) Gaurav Verma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cerebellar Axon/Myelin Loss, Angiogenic Sprouting, and Neuronal Increase of Vascular Endothelial Growth Factor in a Preterm Infant with Kernicterus

(2011) Maria A. Brito et al.   JOURNAL OF CHILD NEUROLOGY

Bax and Calpain Mediate Excitotoxic Oligodendrocyte Death Induced by Activation of Both AMPA and Kainate Receptors

(2011) M. V. Sanchez-Gomez et al.   JOURNAL OF NEUROSCIENCE

Partial XBP1 knockdown does not affect viability of oligodendrocyte precursor cells exposed to new models of hypoxia and ischemia in vitro

(2011) Honorata Kraskiewicz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Selective vulnerability of rat brain regions to unconjugated bilirubin

(2011) Ana Rita Vaz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Hyperbilirubinemia in the Newborn

(2011) B. J. Lauer et al.   PEDIATRICS IN REVIEW

Bilirubin Injury to Neurons and Glial Cells: New Players, Novel Targets, and Newer Insights

(2011) Dora Brites   SEMINARS IN PERINATOLOGY

Cannabidiol induces intracellular calcium elevation and cytotoxicity in oligodendrocytes

(2010) Susana Mato et al.   GLIA

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways

(2010) Adelaide Fernandes et al.   GLIA

Mechanisms of Regulation of Oligodendrocyte Development by p38 Mitogen-Activated Protein Kinase

(2010) L.-J. Chew et al.   JOURNAL OF NEUROSCIENCE

Neurodevelopmental Outcome of Acute Bilirubin Encephalopathy

(2010) K. Mukhopadhyay et al.   JOURNAL OF TROPICAL PEDIATRICS

Effects of camptothecin, etoposide and Ca2+ on caspase-3 activity and myofibrillar disruption of chicken during postmortem ageing

(2010) Lin Chen et al.   MEAT SCIENCE

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Features of bilirubin-induced reactive microglia: From phagocytosis to inflammation

(2010) Sandra L. Silva et al.   NEUROBIOLOGY OF DISEASE

Calpain as a therapeutic target in traumatic brain injury

(2010) Kathryn E. Saatman et al.   Neurotherapeutics

A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein

(2010) Marta Deganuto et al.   PROTEOMICS

Chronic bilirubin encephalopathy: diagnosis and outcome

(2010) Steven M. Shapiro   Seminars in Fetal & Neonatal Medicine

Advanced Neuroimaging Techniques: Their Role in the Development of Future Fetal and Neonatal Neuroprotection

(2010) Catherine Limperopoulos   SEMINARS IN PERINATOLOGY

Intracellular Ca2+ release through ryanodine receptors contributes to AMPA receptor-mediated mitochondrial dysfunction and ER stress in oligodendrocytes

(2010) A Ruiz et al.   Cell Death & Disease

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

(2009) Joao P. Lopes et al.   AGING CELL

A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells

(2009) Raffaella Calligaris et al.   BMC GENOMICS

Oligodendroglial impact on axonal function and survival – a hypothesis

(2009) Celia Michèle Kassmann et al.   CURRENT OPINION IN NEUROLOGY

Contribution of Inflammatory Processes to Nerve Cell Toxicity by Bilirubin and Efficacy of Potential Therapeutic Agents

(2009) Adelaide Fernandes et al.   CURRENT PHARMACEUTICAL DESIGN

Mitochondria, oxidative stress, and temporal lobe epilepsy

(2009) Simon Waldbaum et al.   EPILEPSY RESEARCH

Bilirubin selectively inhibits cytochromecoxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid

(2009) Ana Rita Vaz et al.   JOURNAL OF NEUROCHEMISTRY

Endoplasmic reticulum stress in disorders of myelinating cells

(2009) Wensheng Lin et al.   NATURE NEUROSCIENCE

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Oligodendrocytes: Susceptibility to injury and involvement in neurologic disease

(2009) E. E. Benarroch   NEUROLOGY

Unconjugated Bilirubin Exposure Impairs Hippocampal Long-Term Synaptic Plasticity

(2009) Fang-Yu Chang et al.   PLoS One

Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction

(2009) Yan Fu et al.   PLoS One

Progress in Periventricular Leukomalacia

(2008) Wenbin Deng et al.   ARCHIVES OF NEUROLOGY

Serial brain MRI and ultrasound findings: Relation to gestational age, bilirubin level, neonatal neurologic status and neurodevelopmental outcome in infants at risk of kernicterus

(2008) Konstantina Gkoltsiou et al.   EARLY HUMAN DEVELOPMENT

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

Caspase-2 Cleavage of BID Is a Critical Apoptotic Signal Downstream of Endoplasmic Reticulum Stress

(2008) J.-P. Upton et al.   MOLECULAR AND CELLULAR BIOLOGY

Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells

(2008) H. Gu et al.   MOLECULAR CANCER THERAPEUTICS

Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

(2007) Maria A. Brito et al.   NEUROBIOLOGY OF DISEASE

Bilirubin injury to neurons: Contribution of oxidative stress and rescue by glycoursodeoxycholic acid

(2007) M BRITO   NEUROTOXICOLOGY