Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation

Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4

(2014) Changchang Liu et al.   MOLECULAR CARCINOGENESIS

MTOR inhibition attenuates DNA damage and apoptosis through autophagy-mediated suppression of CREB1

(2013) Ying Wang et al.   Autophagy

Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts

(2013) Enas A El-Karim et al.   Molecular Cancer

KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma

(2011) Francesca Zammarchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress

(2011) Shukie Ng et al.   Autophagy

Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury

(2011) Ying Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

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(2011) M. T. Rosenfeldt et al.   CARCINOGENESIS

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(2011) Robin Mathew et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

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(2010) Noboru Mizushima et al.   CELL

Overview of macroautophagy regulation in mammalian cells

(2010) Maryam Mehrpour et al.   CELL RESEARCH

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(2010) Chang Hwa Jung et al.   FEBS LETTERS

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

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(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer

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Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Putative Tumor-Suppressive Function of Kruppel-Like Factor 4 in Primary Lung Carcinoma

(2009) W. Hu et al.   CLINICAL CANCER RESEARCH

Targeted Inhibition of Mammalian Target of Rapamycin Signaling Inhibits Tumorigenesis of Colorectal Cancer

(2009) P. Gulhati et al.   CLINICAL CANCER RESEARCH

Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable

(2009) E G Hagos et al.   ONCOGENE

Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells

(2008) Paul M Evans et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Jiefei Geng et al.   EMBO REPORTS

eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy

(2008) Francisco Ramírez-Valle et al.   JOURNAL OF CELL BIOLOGY