The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway

Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia

(2016) N. Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension

(2016) Laszlo Kovacs et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Calpains and Coronary Vascular Disease

(2016) Brittany A. Potz et al.   CIRCULATION JOURNAL

Thrombin-Induced Platelet-Fibrin Clot Strength Identified by Thrombelastography

(2016) Kevin P. Bliden et al.   JOURNAL OF INTERVENTIONAL CARDIOLOGY

Calpastatin inhibits motor neuron death and increases survival of hSOD1G93Amice

(2016) Mala V. Rao et al.   JOURNAL OF NEUROCHEMISTRY

Associations Between Target Lesion Restenosis and Drug-Eluting Balloon Use

(2016) Wei-Chieh Lee et al.   MEDICINE

Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration

(2016) Michel Baudry et al.   TRENDS IN NEUROSCIENCES

Efficacy of Various Percutaneous Interventions for In-Stent Restenosis

(2015) Ankur Sethi et al.   Circulation-Cardiovascular Interventions

Evodiamine Attenuates PDGF-BB-Induced Migration of Rat Vascular Smooth Muscle Cells through Activating PPARγ

(2015) Xie Ge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ROS-Induced Nuclear Translocation of Calpain-2 Facilitates Cardiomyocyte Apoptosis in Tail-Suspended Rats

(2015) Hui Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases

(2015) Andreia L Bates et al.   JOURNAL OF PATHOLOGY

Calpain-1 Mediated Disorder of Pyrophosphate Metabolism Contributes to Vascular Calcification Induced by oxLDL

(2015) Futian Tang et al.   PLoS One

Over-Expression of Calpastatin Inhibits Calpain Activation and Attenuates Post-Infarction Myocardial Remodeling

(2015) Tingqiao Ye et al.   PLoS One

Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes

(2014) Bainian Chen et al.   Cardiovascular Diabetology

Novel potential targets for prevention of arterial restenosis: insights from the pre-clinical research

(2014) Amalia Forte et al.   CLINICAL SCIENCE

Resveratrol inhibits glucose-induced migration of vascular smooth muscle cells mediated by focal adhesion kinase

(2014) Yi-Chiao Lin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Downregulation of miR-124 in MPTP-treated mouse model of Parkinson’s disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins

(2014) N. Kanagaraj et al.   NEUROSCIENCE

Significant role of μ-calpain (CANP1) in proliferation/survival of bovine skeletal muscle satellite cells

(2013) Hoa Van Ba et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Mechanism of matrix metalloproteinase axis-induced neointimal growth

(2013) Ling Guo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Prevention of neointimal hyperplasia in balloon-injured rat carotid artery via small interference RNA mediated downregulation of osteopontin gene

(2013) Jian Xu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Statin inhibits hypoxia-induced endothelin-1 via accelerated degradation of HIF-1α in vascular smooth muscle cells

(2012) Tetsuya Hisada et al.   CARDIOVASCULAR RESEARCH

Calpain-1 Regulation of Matrix Metalloproteinase 2 Activity in Vascular Smooth Muscle Cells Facilitates Age-Associated Aortic Wall Calcification and Fibrosis

(2012) Liqun Jiang et al.   HYPERTENSION

Distinct Regulatory Functions of Calpain 1 and 2 during Neural Stem Cell Self-Renewal and Differentiation

(2012) Daniela M. Santos et al.   PLoS One

Restenosis

(2011) Vasim Farooq et al.   Circulation-Cardiovascular Interventions

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

(2011) Wanli Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Suppression of NHE1 by small interfering RNA inhibits HIF-1α-induced angiogenesis in vitro via modulation of calpain activity

(2010) Xian-Gang Mo et al.   MICROVASCULAR RESEARCH

Calpain 2 is Required for Glioblastoma Cell Invasion: Regulation of Matrix Metalloproteinase 2

(2010) Hyo Sang Jang et al.   NEUROCHEMICAL RESEARCH

Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs

(2009) Marco Busnelli et al.   ATHEROSCLEROSIS

Vascular endothelial cell-derived endothelin-1 mediates vascular inflammation and neointima formation following blood flow cessation

(2009) Dyah W. Anggrahini et al.   CARDIOVASCULAR RESEARCH

Percutaneous coronary interventions for non-acute coronary artery disease: a quantitative 20-year synopsis and a network meta-analysis

(2009) Thomas A Trikalinos et al.   LANCET

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression

(2008) C. Blazquez et al.   CANCER RESEARCH

Targeting the Calpain/Calpastatin System as a New Strategy to Prevent Cardiovascular Remodeling in Angiotensin II–Induced Hypertension

(2008) Emmanuel Letavernier et al.   CIRCULATION RESEARCH

Primary Prevention of Cardiovascular Mortality and Events With Statin Treatments

(2008) Edward J. Mills et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Increased Aortic Calpain-1 Activity Mediates Age-Associated Angiotensin II Signaling of Vascular Smooth Muscle Cells

(2008) Liqun Jiang et al.   PLoS One