The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis

Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2

(2016) Gholamreza Hassanzadeh et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs

(2016) Xiao-Ou Zhang et al.   GENOME RESEARCH

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation

(2016) Sudipta Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells

(2016) Benjamin Joachim Schmiedel et al.   Nature Communications

Mini Review: Circular RNAs as Potential Clinical Biomarkers for Disorders in the Central Nervous System

(2016) Dan Lu et al.   Frontiers in Genetics

Mechanism, factors, and physiological role of nonsense-mediated mRNA decay

(2015) Tobias Fatscher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research

(2015) Jonàs Juan-Mateu et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Meta-Analysis of Multiple Sclerosis Microarray Data Reveals Dysregulation in RNA Splicing Regulatory Genes

(2015) Elvezia Paraboschi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation

(2015) Mehmet Yabas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis

(2015) E. Peelen et al.   MOLECULAR IMMUNOLOGY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes

(2015) A Sveen et al.   ONCOGENE

Exon Circularization Requires Canonical Splice Signals

(2015) Stefan Starke et al.   Cell Reports

Defective structural RNA processing in relapsing-remitting multiple sclerosis

(2015) Charles F Spurlock et al.   GENOME BIOLOGY

Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

(2015) Sebastian Memczak et al.   PLoS One

Revised diagnostic criteria of multiple sclerosis

(2014) Ron Milo et al.   AUTOIMMUNITY REVIEWS

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis

(2014) E. M. Paraboschi et al.   HUMAN MOLECULAR GENETICS

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Gasdermin-B Promotes Invasion and Metastasis in Breast Cancer Cells

(2014) Marta Hergueta-Redondo et al.   PLoS One

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

Circular RNAs: diversity of form and function

(2014) Erika Lasda et al.   RNA

Expression of GSDML Associates with Tumor Progression in Uterine Cervix Cancer

(2014) Qiao Sun et al.   Translational Oncology

The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts

(2013) Faer S Morrison et al.   BMC GENOMICS

Alternative splicing and proteolytic rupture contribute to the generation of soluble IL-6 receptors (sIL-6R) in rheumatoid arthritis

(2013) José Ramón Lamas et al.   CYTOKINE

Circular RNAs: splicing’s enigma variations

(2013) Matthias W Hentze et al.   EMBO JOURNAL

MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients

(2013) Michael Hecker et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Correction: Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

17q12-21 Variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom

(2012) Susana Marinho et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

Deregulated inflammasome signaling in disease

(2011) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

Alu-derived cis-element regulates tumorigenesis-dependent gastric expression of GASDERMIN B (GSDMB)

(2010) Hiromitsu Komiyama et al.   GENES & GENETIC SYSTEMS

Alternative splicing of interleukin-7 (IL-7) and interleukin-7 receptor alpha (IL-7Rα) in peripheral blood from patients with multiple sclerosis (MS)

(2010) Lalit Rane et al.   JOURNAL OF NEUROIMMUNOLOGY

Alternative splicing in multiple sclerosis and other autoimmune diseases

(2010) Irina Evsyukova et al.   RNA Biology

The pathobiology of splicing

(2009) Amanda J Ward et al.   JOURNAL OF PATHOLOGY

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls

(2009) Andreas Keller et al.   PLoS One

The emerging role of splicing factors in cancer

(2008) Ana Rita Grosso et al.   EMBO REPORTS

Distinctive expression and function of fourGSDMfamily genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium

(2008) Norihisa Saeki et al.   GENES CHROMOSOMES & CANCER

Multiple sclerosis—a global disorder and still poorly managed

(2008) Alan J Thompson   LANCET NEUROLOGY

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Differential expression and localisation of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic, and colon tissues

(2007) Stacy Carl-McGrath et al.   PATHOLOGY