Impact of Methods on the Measurement of mRNA Turnover

mRNA decay is regulated via sequestration of the conserved 5′-3′ exoribonuclease Xrn1 at eisosome in yeast

(2017) Katarína Vaškovičová et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

(2017) Linda Lauinger et al.   Nature Chemical Biology

Role for dithiolopyrrolones in disrupting bacterial metal homeostasis

(2017) Andrew N. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA exosome and RNA exosome-linked disease

(2017) Derrick J. Morton et al.   RNA

Measurement of In Vivo Protein Binding Affinities in a Signaling Network with Mass Spectrometry

(2017) Mumun Gencoglu et al.   ACS Synthetic Biology

Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex

(2017) Clémentine Delan-Forino et al.   PLoS Genetics

The landscape of transcription errors in eukaryotic cells

(2017) Jean-Francois Gout et al.   Science Advances

Multiplexed gene control reveals rapid mRNA turnover

(2017) Antoine Baudrimont et al.   Science Advances

Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage

(2017) Barbara N. Borsos et al.   Scientific Reports

Genome-Wide Analysis of RNA Secondary Structure

(2016) Philip C. Bevilacqua et al.   Annual Review of Genetics

Connections Underlying Translation and mRNA Stability

(2016) Aditya Radhakrishnan et al.   JOURNAL OF MOLECULAR BIOLOGY

Stem–loop RNA labeling can affect nuclear and cytoplasmic mRNA processing

(2016) Stephanie Heinrich et al.   RNA

Protein Dimerization Generates Bistability in Positive Feedback Loops

(2016) Chieh Hsu et al.   Cell Reports

XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts

(2016) Paul A. Rowley et al.   PLoS Pathogens

Cellular 5′-3′ mRNA Exonuclease Xrn1 Controls Double-Stranded RNA Accumulation and Anti-Viral Responses

(2015) Hannah M. Burgess et al.   Cell Host & Microbe

Improved age determination of blood and teeth samples using a selected set of DNA methylation markers

(2015) Bram Bekaert et al.   Epigenetics

Coupling and Coordination in Gene Expression Processes with Pre-mRNA Splicing

(2015) Kewu Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli

(2015) H. Chen et al.   Molecular Systems Biology

Combinatorial gene regulation by modulation of relative pulse timing

(2015) Yihan Lin et al.   NATURE

Phosphorus-32, a Clinically Available Drug, Inhibits Cancer Growth by Inducing DNA Double-Strand Breakage

(2015) Yulan Cheng et al.   PLoS One

Complex host genetic susceptibility to Staphylococcus aureus infections

(2015) Sanjay K. Shukla et al.   TRENDS IN MICROBIOLOGY

UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan

(2015) Arpan C. Ghosh et al.   Scientific Reports

Cytoplasmic Control of Sense-Antisense mRNA Pairs

(2015) Flore Sinturel et al.   Cell Reports

Coupling mRNA Synthesis and Decay

(2014) K. A. Braun et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantification of pre-mRNA escape rate and synergy in splicing

(2014) Marie Mi Bonde et al.   NUCLEIC ACIDS RESEARCH

Determination of in vivo RNA kinetics using RATE-seq

(2014) Benjamin Neymotin et al.   RNA

Measurement of mRNA Decay Rates in Saccharomyces cerevisiae Using rpb1-1 Strains

(2014) Megan Peccarelli et al.   Jove-Journal of Visualized Experiments

Eukaryotic mRNA Decay: Methodologies, Pathways, and Links to Other Stages of Gene Expression

(2013) José E. Pérez-Ortín et al.   JOURNAL OF MOLECULAR BIOLOGY

Global Analysis of Eukaryotic mRNA Degradation Reveals Xrn1-Dependent Buffering of Transcript Levels

(2013) Mai Sun et al.   MOLECULAR CELL

4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response

(2013) Kaspar Burger et al.   RNA Biology

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Deciphering the Antimicrobial Activity of Phenanthroline Chelators

(2012) M. McCann et al.   CURRENT MEDICINAL CHEMISTRY

Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution

(2012) L. Windhager et al.   GENOME RESEARCH

Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals

(2012) H. Tani et al.   GENOME RESEARCH

Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

(2012) M. Sun et al.   GENOME RESEARCH

Global analysis of mRNA decay intermediates in Saccharomyces cerevisiae

(2012) Y. Harigaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide technology for determining RNA stability in mammalian cells

(2012) Hidenori Tani et al.   RNA Biology

Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution

(2012) Chieh Hsu et al.   Nature Communications

Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decay

(2011) Sarah E. Munchel et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

(2011) C. Miller et al.   Molecular Systems Biology

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

(2011) Michal Rabani et al.   NATURE BIOTECHNOLOGY

Synergy of Repression and Silencing Gradients Along the Chromosome

(2009) Prasuna Ratna et al.   JOURNAL OF MOLECULAR BIOLOGY

High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay

(2008) L. Dolken et al.   RNA

The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast

(2007) Vicent Pelechano et al.   YEAST