Quantification of pre-mRNA escape rate and synergy in splicing

Long Open Reading Frame Transcripts Escape Nonsense-Mediated mRNA Decay in Yeast

(2014) Laurence Decourty et al.   Cell Reports

Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation

(2013) Justin J.-L. Wong et al.   CELL

FISH-quant: automatic counting of transcripts in 3D FISH images

(2013) Florian Mueller et al.   NATURE METHODS

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

(2013) Q. Zhang et al.   Open Biology

To the pore and through the pore: A story of mRNA export kinetics

(2012) Marlene Oeffinger et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Single-mRNA counting using fluorescent in situ hybridization in budding yeast

(2012) Tatjana Trcek et al.   Nature Protocols

Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins

(2012) Mo Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution

(2012) Chieh Hsu et al.   Nature Communications

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

(2012) Cyrille Girard et al.   Nature Communications

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins

(2012) Stephanie C. Huelga et al.   Cell Reports

Biomedical Engineering Strategies in System Design Space

(2011) Michael A. Savageau   ANNALS OF BIOMEDICAL ENGINEERING

The intronome of budding yeasts

(2011) Cécile Neuvéglise et al.   COMPTES RENDUS BIOLOGIES

Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation

(2011) Ute Schmidt et al.   JOURNAL OF CELL BIOLOGY

RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD

(2011) Lulu Huang et al.   MOLECULAR CELL

Cell-to-cell variability of alternative RNA splicing

(2011) Z. Waks et al.   Molecular Systems Biology

Coupled pre-mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli

(2011) A. Zeisel et al.   Molecular Systems Biology

SUS1 introns are required for efficient mRNA nuclear export in yeast

(2011) Bernardo Cuenca-Bono et al.   NUCLEIC ACIDS RESEARCH

Key features of the two-intron Saccharomyces cerevisiae gene SUS1 contribute to its alternative splicing

(2011) Munshi Azad Hossain et al.   NUCLEIC ACIDS RESEARCH

Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing

(2011) Stuart Aitken et al.   PLoS Computational Biology

Robust Network Topologies for Generating Switch-Like Cellular Responses

(2011) Najaf A. Shah et al.   PLoS Computational Biology

Integration of a splicing regulatory network within the meiotic gene expression program of Saccharomyces cerevisiae

(2010) E. M. Munding et al.   GENES & DEVELOPMENT

Splicing-Dependent RNA Polymerase Pausing in Yeast

(2010) Ross D. Alexander et al.   MOLECULAR CELL

Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

(2010) Fernando Carrillo Oesterreich et al.   MOLECULAR CELL

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Spatial Epigenetic Control of Mono- and Bistable Gene Expression

(2010) János Z. Kelemen et al.   PLOS BIOLOGY

Alternative Splicing of PTC7 in Saccharomyces cerevisiae Determines Protein Localization

(2009) K. Juneau et al.   GENETICS

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

Rates of in situ transcription and splicing in large human genes

(2009) Jarnail Singh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stochastic noise in splicing machinery

(2009) Eugene Melamud et al.   NUCLEIC ACIDS RESEARCH

Widespread Impact of Nonsense-Mediated mRNA Decay on the Yeast Intronome

(2008) Shakir Sayani et al.   MOLECULAR CELL

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY