FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes

Mesenchymal stem cells and differentiated insulin producing cells are new horizons for pancreatic regeneration in type I diabetes mellitus

(2017) Ayat M. Domouky et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pancreatic β-cell regeneration: Facultative or dedicated progenitors?

(2017) Solomon Afelik et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Co-localization of acinar markers and insulin in pancreatic cells of subjects with type 2 diabetes

(2017) Matilde Masini et al.   PLoS One

A Unified Pathophysiological Construct of Diabetes and its Complications

(2017) Stanley S. Schwartz et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genomics of Islet (Dys)function and Type 2 Diabetes

(2017) Nathan Lawlor et al.   TRENDS IN GENETICS

Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved

(2017) Solomon Afelik et al.   Genome Medicine

Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions

(2017) Elena F. Jacobson et al.   Journal of Biological Engineering

Circulating microRNAs and diabetes mellitus: a novel tool for disease prediction, diagnosis, and staging?

(2017) G. Sebastiani et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

β-Cell Replacement Strategies: The Increasing Need for a “β-Cell Dogma”

(2017) Andhira Vieira et al.   Frontiers in Genetics

MiRNAs in β-Cell Development, Identity, and Disease

(2017) Aida Martinez-Sanchez et al.   Frontiers in Genetics

Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes

(2017) Chad S. Hunter et al.   Frontiers in Genetics

Genetic Factors of Diabetes

(2016) Karolina Antosik et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

β-Cell adaptation in pregnancy

(2016) L. Baeyens et al.   DIABETES OBESITY & METABOLISM

Serotonin competence of mouse beta cells during pregnancy

(2016) Lotte Goyvaerts et al.   DIABETOLOGIA

Replicative capacity of β-cells and type 1 diabetes

(2016) Diane Saunders et al.   JOURNAL OF AUTOIMMUNITY

Impact of islet architecture on β-cell heterogeneity, plasticity and function

(2016) Sara S. Roscioni et al.   Nature Reviews Endocrinology

How to make insulin-producing pancreatic β cells for diabetes treatment

(2016) Jiaqi Lu et al.   Science China-Life Sciences

Lineage Reprogramming: A Promising Road for Pancreatic β Cell Regeneration

(2016) Rui Wei et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

β-cell replacement sources for type 1 diabetes: a focus on pancreatic ductal cells

(2016) Elisa Corritore et al.   Therapeutic Advances in Endocrinology and Metabolism

Umbilical Cord Derived Mesenchymal Stem Cells Useful in Insulin Production - Another Opportunity in Cell Therapy

(2016) Shabari Sarang et al.   International Journal of Stem Cells

Epidemiological Perspectives of Diabetes

(2015) Ziqi Tao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development

(2015) Béatrice Assouline-Thomas et al.   DIFFERENTIATION

Differentiation of human skin-derived precursor cells into functional islet-like insulin-producing cell clusters

(2015) Maryam Mehrabi et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development, growth and maintenance of β-cell mass: Models are also part of the story

(2015) Anmar Khadra et al.   MOLECULAR ASPECTS OF MEDICINE

Transcription factor regulation of pancreatic organogenesis, differentiation and maturation

(2015) Reshmi Dassaye et al.   Islets

Stem cells for pancreatic β-cell replacement in diabetes mellitus

(2014) Riccardo Calafiore et al.   Current Opinion in Organ Transplantation

Importance of diabetic nephropathy in childhood. Clinical findings and basic research in the past decades

(2014) Andrea Fekete et al.   ORVOSI HETILAP

β-Cell differentiation and regeneration in type 1 diabetes

(2013) L. Ding et al.   DIABETES OBESITY & METABOLISM

Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes

(2013) S. Yoneda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Current status of regeneration of pancreatic β-cells

(2013) Kohtaro Minami et al.   Journal of Diabetes Investigation

Regeneration of pancreatic beta-cell mass for the treatment of diabetes

(2012) Juan Domínguez-Bendala et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Present and future cell therapies for pancreatic beta cell replenishment

(2012) Juan Domínguez-Bendala   WORLD JOURNAL OF GASTROENTEROLOGY

Lineage Tracing Evidence for Transdifferentiation of Acinar to Duct Cells and Plasticity of Human Pancreas

(2011) Isabelle Houbracken et al.   GASTROENTEROLOGY

Human placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets

(2011) Marco F. Lombardo et al.   Islets

Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy

(2010) A. E. Butler et al.   DIABETOLOGIA

c-Kit and stem cell factor regulate PANC-1 cell differentiation into insulin- and glucagon-producing cells

(2010) Yuexiu Wu et al.   LABORATORY INVESTIGATION

Serotonin regulates pancreatic beta cell mass during pregnancy

(2010) Hail Kim et al.   NATURE MEDICINE

Isolated human islets contain a distinct population of mesenchymal stem cells

(2010) Françoise Carlotti et al.   Islets

Can pancreatic duct-derived progenitors be a source of islet regeneration?

(2009) Bing Xia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genome-wide association studies in type 1 diabetes

(2009) Struan F.A. Grant et al.   Current Diabetes Reports

Pdx1 and other factors that regulate pancreatic β-cell survival

(2009) K. Fujimoto et al.   DIABETES OBESITY & METABOLISM

Differentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouse

(2009) R. Kikugawa et al.   DIABETOLOGIA

Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells

(2009) Melanie Marchand et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

FGF2 Specifies hESC-Derived Definitive Endoderm into Foregut/Midgut Cell Lineages in a Concentration-Dependent Manner

(2009) Jacqueline Ameri et al.   STEM CELLS

Transdifferentiation of pancreatic ductal cells to endocrine β-cells

(2008) Susan Bonner-Weir et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Recovery of Endogenous  -Cell Function in Nonhuman Primates After Chemical Diabetes Induction and Islet Transplantation

(2008) R. Bottino et al.   DIABETES

Pancreatic β-cell mass in European subjects with type 2 diabetes

(2008) J. Rahier et al.   DIABETES OBESITY & METABOLISM

Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity

(2008) A. Martin-Pagola et al.   DIABETOLOGIA

Beta Cells within Single Human Islets Originate from Multiple Progenitors

(2008) Raphaël Scharfmann et al.   PLoS One

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

(2008) A. Inada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA