Current status of regeneration of pancreatic β-cells

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Ectopic Expression of GIP in Pancreatic  -Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides

(2012) A. Fukami et al.   DIABETES

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets

(2012) P. Marchetti et al.   DIABETOLOGIA

Pancreatic β-cells are generated by neogenesis from non-β-cells after birth

(2011) Korefumi Nakamura et al.   BIOMEDICAL RESEARCH-TOKYO

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

(2011) Fabrizio Thorel et al.   DIABETES

Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells

(2011) A. Jermendy et al.   DIABETOLOGIA

Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation

(2011) E. Hakonen et al.   DIABETOLOGIA

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

(2011) Susumu Seino et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro

(2011) Holger A. Russ et al.   PLoS One

In vitro generation of insulin-secreting cells from human pancreatic exocrine cells

(2011) Kohtaro Minami et al.   Journal of Diabetes Investigation

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

(2010) Toshihiro Kobayashi et al.   CELL

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

(2010) C. Aguayo-Mazzucato et al.   DIABETOLOGIA

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Pancreatic β-cell signaling: toward better understanding of diabetes and its treatment

(2010) Susumu SEINO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic  -like cells

(2010) Z. Alipio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracing phenotypic reversibility of pancreatic β-cells in vitro

(2010) Kohtaro Minami et al.   Journal of Diabetes Investigation

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

(2009) Myriam Solar et al.   DEVELOPMENTAL CELL

Notch Signaling as Gatekeeper of Rat Acinar-to-β-Cell Conversion in Vitro

(2009) Luc Baeyens et al.   GASTROENTEROLOGY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial-Mesenchymal Transition in Cells Expanded In Vitro from Lineage-Traced Adult Human Pancreatic Beta Cells

(2009) Holger A. Russ et al.   PLoS One

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Pancreatic acinar-to-beta cell transdifferentiation in vitro

(2008) Kohtaro Minami   Frontiers in Bioscience-Landmark

Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts

(2008) Keisuke Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Cadherin-mediated Cell-Cell Adhesion in Pancreatic Exocrine-to-Endocrine Transdifferentiation

(2008) Kohtaro Minami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

(2008) A. Inada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Pancreatic   Cell Mass by Neuronal Signals from the Liver

(2008) J. Imai et al.   SCIENCE