Overexpression of SIRT2 Alleviates Neuropathic Pain and Neuroinflammation Through Deacetylation of Transcription Factor Nuclear Factor-Kappa B

Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway

(2017) Éva M. Szegő et al.   NEUROBIOLOGY OF AGING

SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action

(2017) Mercedes Erburu et al.   NEUROPHARMACOLOGY

Differential Expression of Tubulin Acetylase and Deacetylase Between the Damaged Central and Peripheral Branch of Dorsal Root Ganglion Neurons

(2017) Zhiyi Fu et al.   MEDICAL SCIENCE MONITOR

Sirtuin 2 Regulates Microvascular Inflammation during Sepsis

(2017) Nancy Buechler et al.   Journal of Immunology Research

Characterization and Fine Mapping of a Blast Resistant Gene Pi-jnw1 from the japonica Rice Landrace Jiangnanwan

(2017) Ruisen Wang et al.   PLoS One

Joint estimation of multiple dependent Gaussian graphical models with applications to mouse genomics

(2016) Yuying Xie et al.   BIOMETRIKA

High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects

(2016) Jingwen Yu et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer’s-Disease Related Pathology

(2016) D. F. Silva et al.   MOLECULAR NEUROBIOLOGY

SIRT2 Plays Significant Roles in Lipopolysaccharides-Induced Neuroinflammation and Brain Injury in Mice

(2016) Ban Wang et al.   NEUROCHEMICAL RESEARCH

Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons

(2016) Ji Hye Park et al.   Scientific Reports

Knockout of Silent Information Regulator 2 (SIRT2) Preserves Neurological Function after Experimental Stroke in Mice

(2015) Lea Krey et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

SIRT2 inhibition exacerbates neuroinflammation and blood-brain barrier disruption in experimental traumatic brain injury by enhancing NF-κB p65 acetylation and activation

(2015) Fang Yuan et al.   JOURNAL OF NEUROCHEMISTRY

SIRT2 is required for lipopolysaccharide-induced activation of BV2 microglia

(2015) Heyu Chen et al.   NEUROREPORT

Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7

(2015) Xijin Wang et al.   Drug Design Development and Therapy

SIRT2 is involved in the modulation of depressive behaviors

(2015) Rui Liu et al.   Scientific Reports

SIRT2 ameliorates lipopolysaccharide-induced inflammation in macrophages

(2014) Ae Sin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcriptional Consequence and Impaired Gametogenesis with High-Grade Aneuploidy in Arabidopsis thaliana

(2014) Kuan-Lin Lo et al.   PLoS One

Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways

(2014) C Valle et al.   Cell Death & Disease

Sirt2 suppresses inflammatory responses in collagen-induced arthritis

(2013) Jiangtao Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer

(2013) Yong I. Cha et al.   BMB Reports

The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation

(2013) Teresa Faria Pais et al.   EMBO JOURNAL

PEP-1–SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages

(2013) Mi Jin Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Novel Sirtuin 2 (SIRT2) Inhibitor with p53-dependent Pro-apoptotic Activity in Non-small Cell Lung Cancer

(2013) Gesine Hoffmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endovascular Therapy in Acute Ischemic Stroke

(2013) Robert M. Starke et al.   NEUROSURGERY

hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562

(2013) Jian Ma et al.   PLoS One

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

(2012) Robert E Sorge et al.   NATURE MEDICINE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

(2011) Michele M. Maxwell et al.   HUMAN MOLECULAR GENETICS

SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310

(2010) K. M. Rothgiesser et al.   JOURNAL OF CELL SCIENCE

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

(2010) Ruth Luthi-Carter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of Neuropathic Pain: An Overview of Recent Guidelines

(2009) Alec B. O'Connor et al.   AMERICAN JOURNAL OF MEDICINE

SIRT2-mediated protein deacetylation: An emerging key regulator in brain physiology and pathology

(2009) Kai Harting et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Prevalence of chronic pain with neuropathic characteristics in the general population

(2007) Didier Bouhassira et al.   PAIN