Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways

Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression

(2013) Gaëlle Bruneteau et al.   BRAIN

Aging Well with a Little Wine and a Good Clock

(2013) William J. Belden et al.   CELL

Sirtuins as therapeutic targets of ALS

(2013) Giulio Maria Pasinetti et al.   CELL RESEARCH

Histone Acetylation as a Potential Therapeutic Target in Motor Neuron Degenerative Diseases

(2013) Lutz Garbes et al.   CURRENT PHARMACEUTICAL DESIGN

SIRT1 and SIRT2: emerging targets in neurodegeneration

(2013) Gizem Donmez et al.   EMBO Molecular Medicine

Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS

(2013) Ines Taes et al.   HUMAN MOLECULAR GENETICS

Sirtuins: the molecular basis of beneficial effects of physical activity

(2013) Bruna Pucci et al.   Internal and Emergency Medicine

HDAC6 Regulates Mutant SOD1 Aggregation through Two SMIR Motifs and Tubulin Acetylation

(2013) Jozsef Gal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New role of silent information regulator 1 in cerebral ischemia

(2013) Yang Yang et al.   NEUROBIOLOGY OF AGING

SIRT1 and energy metabolism

(2012) X. Li   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Janus-faced role of SIRT1 in tumorigenesis

(2012) Na-Young Song et al.   Annals of the New York Academy of Sciences

Amyotrophic Lateral Sclerosis: New Insights into Underlying Molecular Mechanisms and Opportunities for Therapeutic Intervention

(2012) Mauro Cozzolino et al.   ANTIOXIDANTS & REDOX SIGNALING

Histone Deacetylation and Motor Neuron Degeneration

(2012) S. Schmalbach et al.   CNS & Neurological Disorders-Drug Targets

Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α

(2012) Wenjun Song et al.   NEUROBIOLOGY OF DISEASE

Differential Sirtuin Expression Patterns in Amyotrophic Lateral Sclerosis (ALS) Postmortem Tissue: Neuroprotective or Neurotoxic Properties of Sirtuins in ALS?

(2012) Sonja Körner et al.   Neurodegenerative Diseases

HDAC6 at the Intersection of Neuroprotection and Neurodegeneration

(2012) Constantin d'Ydewalle et al.   TRAFFIC

The neurobiology of sirtuins and their role in neurodegeneration

(2012) Gizem Donmez   TRENDS IN PHARMACOLOGICAL SCIENCES

Region-specific changes in the immunoreactivity of SIRT1 expression in the central nervous system of SOD1G93A transgenic mice as an in vivo model of amyotrophic lateral sclerosis

(2011) Jae Chul Lee et al.   BRAIN RESEARCH

Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis

(2011) Young-Eun Yoo et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation

(2011) M. G. Pesaresi et al.   HUMAN MOLECULAR GENETICS

Sirtuins at a glance

(2011) T. Nakagawa et al.   JOURNAL OF CELL SCIENCE

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6

(2011) Fabienne C Fiesel et al.   Molecular Neurodegeneration

Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

(2011) Claudia Crosio et al.   PLoS One

Protective effects and mechanisms of sirtuins in the nervous system

(2011) Feng Zhang et al.   PROGRESS IN NEUROBIOLOGY

Differential Histone Deacetylase mRNA Expression Patterns in Amyotrophic Lateral Sclerosis

(2010) Claas Janssen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

(2009) A. H. Williams et al.   SCIENCE

Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice

(2008) Steven J. Del Signore et al.   Amyotrophic Lateral Sclerosis