SIRT2 is involved in the modulation of depressive behaviors

SIRT1 and SIRT2: emerging targets in neurodegeneration

(2013) Gizem Donmez et al.   EMBO Molecular Medicine

Brain Activation of SIRT1: Role in Neuropathology

(2013) Alanna Fernandes Paraíso et al.   MOLECULAR NEUROBIOLOGY

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

(2013) Frederick A. Schroeder et al.   PLoS One

Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition

(2012) Deepika Suri et al.   BIOLOGICAL PSYCHIATRY

Altered sirtuin deacetylase gene expression in patients with a mood disorder

(2011) Naoko Abe et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling

(2011) J C Garza et al.   MOLECULAR PSYCHIATRY

Cognitive Mechanisms of Treatment in Depression

(2011) Jonathan P Roiser et al.   NEUROPSYCHOPHARMACOLOGY

Reduction of Adult Hippocampal Neurogenesis Confers Vulnerability in an Animal Model of Cocaine Addiction

(2010) M. A. Noonan et al.   JOURNAL OF NEUROSCIENCE

SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity

(2010) S. Michan et al.   JOURNAL OF NEUROSCIENCE

Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment

(2010) Marianne H. Larsen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

A negative regulator of MAP kinase causes depressive behavior

(2010) Vanja Duric et al.   NATURE MEDICINE

Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish

(2009) Rupert J. Egan et al.   BEHAVIOURAL BRAIN RESEARCH

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Potential Role of Sirtuin as a Therapeutic Target for Neurodegenerative Diseases

(2009) Seol-Heui Han   Journal of Clinical Neurology

Antidepressant Actions of Histone Deacetylase Inhibitors

(2009) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   BIOLOGICAL PSYCHIATRY

Inhibitors of NAD+ Dependent Histone Deacetylases (Sirtuins)

(2008) Manfred Jung et al.   CURRENT PHARMACEUTICAL DESIGN