The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Authors
Keywords
-
Journal
IMMUNOLOGY AND CELL BIOLOGY
Volume 96, Issue 1, Pages 81-99
Publisher
Wiley
Online
2018-01-12
DOI
10.1111/imcb.1018
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
- (2017) Avi Ashkenazi et al. NATURE REVIEWS DRUG DISCOVERY
- Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation
- (2017) Stefanie Ginster et al. PLoS One
- The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling
- (2016) Tiphaine Douanne et al. JOURNAL OF CELL SCIENCE
- MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation
- (2016) Anja Schmitt et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms
- (2015) Takashi Mino et al. CELL
- The common γ-chain cytokine receptor: tricks-and-treats for T cells
- (2015) Adam T. Waickman et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The paracaspase MALT1: biological function and potential for therapeutic inhibition
- (2015) Maike Jaworski et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling
- (2015) Lynn Elton et al. FEBS Journal
- Deficiency of MALT1 Paracaspase Activity Results in Unbalanced Regulatory and Effector T and B Cell Responses Leading to Multiorgan Inflammation
- (2015) Frédéric Bornancin et al. JOURNAL OF IMMUNOLOGY
- Zinc-binding metallothioneins are key modulators of IL-4 production by basophils
- (2015) Tsukasa Ugajin et al. MOLECULAR IMMUNOLOGY
- The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling
- (2015) Theo Klein et al. Nature Communications
- Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity
- (2014) Maike Jaworski et al. EMBO JOURNAL
- Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation
- (2014) Katharina M Jeltsch et al. NATURE IMMUNOLOGY
- MALT1 Auto-Proteolysis Is Essential for NF-κB-Dependent Gene Transcription in Activated Lymphocytes
- (2014) Mathijs Baens et al. PLoS One
- Noncanonical NF- B Signaling Is Limited by Classical NF- B Activity
- (2014) C. M. Gray et al. Science Signaling
- Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation
- (2014) Andreas Gewies et al. Cell Reports
- Structural Analysis of Phenothiazine Derivatives as Allosteric Inhibitors of the MALT1 Paracaspase
- (2013) Florian Schlauderer et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation
- (2013) Takuya Uehata et al. CELL
- The Three CARMA Sisters: So Different, So Similar: A Portrait of the Three CARMA Proteins and Their Involvement in Human Disorders
- (2013) Ivan Scudiero et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The protease activity of the paracaspase MALT1 is controlled by monoubiquitination
- (2013) Christiane Pelzer et al. NATURE IMMUNOLOGY
- Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals
- (2013) Paul Koenen et al. Nature Communications
- Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling
- (2012) Ruben L Smeets et al. BMC IMMUNOLOGY
- MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo
- (2012) Lorena Fontan et al. CANCER CELL
- Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL
- (2012) Daniel Nagel et al. CANCER CELL
- Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation
- (2012) Zoran Popmihajlov et al. Frontiers in Immunology
- From MALT lymphoma to the CBM signalosome
- (2011) Shaun Rosebeck et al. CELL CYCLE
- T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1
- (2011) Jens Staal et al. EMBO JOURNAL
- Malt1-dependent RelB cleavage promotes canonical NF- B activation in lymphocytes and lymphoma cell lines
- (2011) S. Hailfinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2
- (2011) Sonja I. Gringhuis et al. PLoS Pathogens
- Expression, biological activities and mechanisms of action of A20 (TNFAIP3)
- (2010) Lynn Verstrepen et al. BIOCHEMICAL PHARMACOLOGY
- Staphylococcal Enterotoxins
- (2010) Irina V. Pinchuk et al. Toxins
- The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation
- (2009) J.-P. Evenou et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20
- (2008) Beatrice Coornaert et al. NATURE IMMUNOLOGY
- The proteolytic activity of the paracaspase MALT1 is key in T cell activation
- (2008) Fabien Rebeaud et al. NATURE IMMUNOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started